These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 25246278)

  • 1. X-ray crystallographic analysis of IMP-1 metallo-β-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors.
    Hiraiwa Y; Saito J; Watanabe T; Yamada M; Morinaka A; Fukushima T; Kudo T
    Bioorg Med Chem Lett; 2014 Oct; 24(20):4891-4. PubMed ID: 25246278
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metallo-β-lactamase inhibitory activity of 3-alkyloxy and 3-amino phthalic acid derivatives and their combination effect with carbapenem.
    Hiraiwa Y; Morinaka A; Fukushima T; Kudo T
    Bioorg Med Chem; 2013 Sep; 21(18):5841-50. PubMed ID: 23920484
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metallo-beta-lactamase inhibitory activity of phthalic acid derivatives.
    Hiraiwa Y; Morinaka A; Fukushima T; Kudo T
    Bioorg Med Chem Lett; 2009 Sep; 19(17):5162-5. PubMed ID: 19632114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase.
    Weston GS; Blázquez J; Baquero F; Shoichet BK
    J Med Chem; 1998 Nov; 41(23):4577-86. PubMed ID: 9804697
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1.
    Arjomandi OK; Hussein WM; Vella P; Yusof Y; Sidjabat HE; Schenk G; McGeary RP
    Eur J Med Chem; 2016 May; 114():318-27. PubMed ID: 27017264
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor.
    Concha NO; Janson CA; Rowling P; Pearson S; Cheever CA; Clarke BP; Lewis C; Galleni M; Frère JM; Payne DJ; Bateson JH; Abdel-Meguid SS
    Biochemistry; 2000 Apr; 39(15):4288-98. PubMed ID: 10757977
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contributions of IMP-10 metallo-beta-lactamase, the outer membrane barrier and the MexAB-OprM efflux system to high-level carbapenem resistance in Pseudomonas aeruginosa.
    Zhao WH; Hu Z; Chen G; Ito R; Hu ZQ
    Chemotherapy; 2009; 55(3):168-74. PubMed ID: 19420932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.
    Toney JH; Hammond GG; Fitzgerald PM; Sharma N; Balkovec JM; Rouen GP; Olson SH; Hammond ML; Greenlee ML; Gao YD
    J Biol Chem; 2001 Aug; 276(34):31913-8. PubMed ID: 11390410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.
    Klingler FM; Wichelhaus TA; Frank D; Cuesta-Bernal J; El-Delik J; Müller HF; Sjuts H; Göttig S; Koenigs A; Pos KM; Pogoryelov D; Proschak E
    J Med Chem; 2015 Apr; 58(8):3626-30. PubMed ID: 25815530
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and kinetic testing of new inhibitors for a metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa.
    Mohamed MS; Hussein WM; McGeary RP; Vella P; Schenk G; Abd El-Hameed RH
    Eur J Med Chem; 2011 Dec; 46(12):6075-82. PubMed ID: 22051063
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors.
    Faridoon ; Hussein WM; Vella P; Islam NU; Ollis DL; Schenk G; McGeary RP
    Bioorg Med Chem Lett; 2012 Jan; 22(1):380-6. PubMed ID: 22115595
    [TBL] [Abstract][Full Text] [Related]  

  • 12. First occurrence of a Pseudomonas aeruginosa isolate in the United States producing an IMP metallo-beta-lactamase, IMP-18.
    Hanson ND; Hossain A; Buck L; Moland ES; Thomson KS
    Antimicrob Agents Chemother; 2006 Jun; 50(6):2272-3. PubMed ID: 16723605
    [No Abstract]   [Full Text] [Related]  

  • 13. In vitro antibacterial activity of a new cephalosporin, FR295389, against IMP-type metallo-beta-lactamase-producers.
    Takeda S; Ikeda F; Hatano K
    J Antibiot (Tokyo); 2008 Jan; 61(1):36-9. PubMed ID: 18305358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbapenem-based prodrugs. Design, synthesis, and biological evaluation of carbapenems.
    Hakimelahi GH; Moosavi-Movahedi AA; Saboury AA; Osetrov V; Khodarahmi GA; Shia KS
    Eur J Med Chem; 2005 Apr; 40(4):339-49. PubMed ID: 15804533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-β-lactamase inhibitors.
    Yan YH; Li W; Chen W; Li C; Zhu KR; Deng J; Dai QQ; Yang LL; Wang Z; Li GB
    Eur J Med Chem; 2022 Jan; 228():113965. PubMed ID: 34763944
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location.
    Pellegrini C; Mercuri PS; Celenza G; Galleni M; Segatore B; Sacchetti E; Volpe R; Amicosante G; Perilli M
    J Antimicrob Chemother; 2009 May; 63(5):901-8. PubMed ID: 19270313
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clinical and bacteriological characteristics of IMP-type metallo-beta-lactamase-producing Pseudomonas aeruginosa.
    Hirakata Y; Yamaguchi T; Nakano M; Izumikawa K; Mine M; Aoki S; Kondoh A; Matsuda J; Hirayama M; Yanagihara K; Miyazaki Y; Tomono K; Yamada Y; Kamihira S; Kohno S
    Clin Infect Dis; 2003 Jul; 37(1):26-32. PubMed ID: 12830405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel IMP-1 metallo-beta-lactamase inhibitors can reverse meropenem resistance in Escherichia coli expressing IMP-1.
    Moloughney JG; D Thomas J; Toney JH
    FEMS Microbiol Lett; 2005 Feb; 243(1):65-71. PubMed ID: 15668002
    [TBL] [Abstract][Full Text] [Related]  

  • 19. First report of the carbapenem-resistant Pseudomonas aeruginosa producing IMP-7 metallo-beta-lactamase in Slovakia.
    Ohlasova D; Kmet V; Niks M
    Int J Antimicrob Agents; 2007 Oct; 30(4):370-1. PubMed ID: 17709230
    [No Abstract]   [Full Text] [Related]  

  • 20. Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors.
    Chonan T; Tanaka H; Yamamoto D; Yashiro M; Oi T; Wakasugi D; Ohoka-Sugita A; Io F; Koretsune H; Hiratate A
    Bioorg Med Chem Lett; 2010 Jul; 20(13):3965-8. PubMed ID: 20537533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.