BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

683 related articles for article (PubMed ID: 25247697)

  • 21. Genome Editing with CRISPR-Cas9: Can It Get Any Better?
    Haeussler M; Concordet JP
    J Genet Genomics; 2016 May; 43(5):239-50. PubMed ID: 27210042
    [TBL] [Abstract][Full Text] [Related]  

  • 22. CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context.
    Corsi GI; Qu K; Alkan F; Pan X; Luo Y; Gorodkin J
    Nat Commun; 2022 May; 13(1):3006. PubMed ID: 35637227
    [TBL] [Abstract][Full Text] [Related]  

  • 23. CT-Finder: A Web Service for CRISPR Optimal Target Prediction and Visualization.
    Zhu H; Misel L; Graham M; Robinson ML; Liang C
    Sci Rep; 2016 May; 6():25516. PubMed ID: 27210050
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies.
    Hoberecht L; Perampalam P; Lun A; Fortin JP
    Nat Commun; 2022 Nov; 13(1):6568. PubMed ID: 36323688
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients.
    Sullivan NT; Dampier W; Chung CH; Allen AG; Atkins A; Pirrone V; Homan G; Passic S; Williams J; Zhong W; Kercher K; Desimone M; Li L; C Antell G; Mell JC; Ehrlich GD; Szep Z; Jacobson JM; Nonnemacher MR; Wigdahl B
    Sci Rep; 2019 Nov; 9(1):17088. PubMed ID: 31745112
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.
    Fonfara I; Richter H; Bratovič M; Le Rhun A; Charpentier E
    Nature; 2016 Apr; 532(7600):517-21. PubMed ID: 27096362
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Whole genome analysis of CRISPR Cas9 sgRNA off-target homologies via an efficient computational algorithm.
    Zhou H; Zhou M; Li D; Manthey J; Lioutikova E; Wang H; Zeng X
    BMC Genomics; 2017 Nov; 18(Suppl 9):826. PubMed ID: 29219081
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Simplified CRISPR-Mediated DNA Editing in Multicellular Eukaryotes.
    Kumar R; Tiwari K; Saudagar P
    Methods Mol Biol; 2023; 2575():241-260. PubMed ID: 36301478
    [TBL] [Abstract][Full Text] [Related]  

  • 29. CasOT: a genome-wide Cas9/gRNA off-target searching tool.
    Xiao A; Cheng Z; Kong L; Zhu Z; Lin S; Gao G; Zhang B
    Bioinformatics; 2014 Apr; 30(8):1180-1182. PubMed ID: 24389662
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir.
    Roychoudhury P; De Silva Feelixge H; Reeves D; Mayer BT; Stone D; Schiffer JT; Jerome KR
    BMC Biol; 2018 Jul; 16(1):75. PubMed ID: 29996827
    [TBL] [Abstract][Full Text] [Related]  

  • 31. CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.
    Lin Y; Cradick TJ; Brown MT; Deshmukh H; Ranjan P; Sarode N; Wile BM; Vertino PM; Stewart FJ; Bao G
    Nucleic Acids Res; 2014 Jun; 42(11):7473-85. PubMed ID: 24838573
    [TBL] [Abstract][Full Text] [Related]  

  • 32. CSC software corrects off-target mediated gRNA depletion in CRISPR-Cas9 essentiality screens.
    Perez AR; Sala L; Perez RK; Vidigal JA
    Nat Commun; 2021 Nov; 12(1):6461. PubMed ID: 34753924
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes.
    Spoto M; Guan C; Fleming E; Oh J
    mSphere; 2020 Feb; 5(1):. PubMed ID: 32051236
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Developing Heritable Mutations in Arabidopsis thaliana Using a Modified CRISPR/Cas9 Toolkit Comprising PAM-Altered Cas9 Variants and gRNAs.
    Yamamoto A; Ishida T; Yoshimura M; Kimura Y; Sawa S
    Plant Cell Physiol; 2019 Oct; 60(10):2255-2262. PubMed ID: 31198958
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Off-target assessment of CRISPR-Cas9 guiding RNAs in human iPS and mouse ES cells.
    Tan EP; Li Y; Velasco-Herrera Mdel C; Yusa K; Bradley A
    Genesis; 2015 Feb; 53(2):225-36. PubMed ID: 25378133
    [TBL] [Abstract][Full Text] [Related]  

  • 36. "Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs.
    Pliatsika V; Rigoutsos I
    Biol Direct; 2015 Jan; 10():4. PubMed ID: 25630343
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Rational guide RNA engineering for small-molecule control of CRISPR/Cas9 and gene editing.
    Liu X; Xiong W; Qi Q; Zhang Y; Ji H; Cui S; An J; Sun X; Yin H; Tian T; Zhou X
    Nucleic Acids Res; 2022 May; 50(8):4769-4783. PubMed ID: 35446403
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Exploiting off-targeting in guide-RNAs for CRISPR systems for simultaneous editing of multiple genes.
    Ferreira R; Gatto F; Nielsen J
    FEBS Lett; 2017 Oct; 591(20):3288-3295. PubMed ID: 28884816
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A catalogue of biochemically diverse CRISPR-Cas9 orthologs.
    Gasiunas G; Young JK; Karvelis T; Kazlauskas D; Urbaitis T; Jasnauskaite M; Grusyte MM; Paulraj S; Wang PH; Hou Z; Dooley SK; Cigan M; Alarcon C; Chilcoat ND; Bigelyte G; Curcuru JL; Mabuchi M; Sun Z; Fuchs RT; Schildkraut E; Weigele PR; Jack WE; Robb GB; Venclovas Č; Siksnys V
    Nat Commun; 2020 Nov; 11(1):5512. PubMed ID: 33139742
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences.
    Mekler V; Kuznedelov K; Severinov K
    J Biol Chem; 2020 May; 295(19):6509-6517. PubMed ID: 32241913
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 35.