287 related articles for article (PubMed ID: 25248717)
1. Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.
Barrio-Real L; Benedetti LG; Engel N; Tu Y; Cho S; Sukumar S; Kazanietz MG
Breast Cancer Res; 2014 Sep; 16(5):441. PubMed ID: 25248717
[TBL] [Abstract][Full Text] [Related]
2. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
Liu HJ; Ooms LM; Srijakotre N; Man J; Vieusseux J; Waters JE; Feng Y; Bailey CG; Rasko JE; Price JT; Mitchell CA
J Biol Chem; 2016 Aug; 291(33):17258-70. PubMed ID: 27358402
[TBL] [Abstract][Full Text] [Related]
3. PtdIns(3,4,5)P
Srijakotre N; Liu HJ; Nobis M; Man J; Yip HYK; Papa A; Abud HE; Anderson KI; Welch HCE; Tiganis T; Timpson P; McLean CA; Ooms LM; Mitchell CA
Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28056-28067. PubMed ID: 33097662
[TBL] [Abstract][Full Text] [Related]
4. Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
Yuan J; Luo RZ; Fujii S; Wang L; Hu W; Andreeff M; Pan Y; Kadota M; Oshimura M; Sahin AA; Issa JP; Bast RC; Yu Y
Cancer Res; 2003 Jul; 63(14):4174-80. PubMed ID: 12874023
[TBL] [Abstract][Full Text] [Related]
5. Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.
Mossman D; Kim KT; Scott RJ
BMC Cancer; 2010 Jul; 10():366. PubMed ID: 20618997
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells.
Wong CY; Wuriyanghan H; Xie Y; Lin MF; Abel PW; Tu Y
J Biol Chem; 2011 Jul; 286(29):25813-22. PubMed ID: 21636851
[TBL] [Abstract][Full Text] [Related]
7. Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma.
Gupta A; Godwin AK; Vanderveer L; Lu A; Liu J
Cancer Res; 2003 Feb; 63(3):664-73. PubMed ID: 12566312
[TBL] [Abstract][Full Text] [Related]
8. MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine.
David GL; Yegnasubramanian S; Kumar A; Marchi VL; De Marzo AM; Lin X; Nelson WG
Cancer Biol Ther; 2004 Jun; 3(6):540-8. PubMed ID: 15034303
[TBL] [Abstract][Full Text] [Related]
9. Characterization of a P-Rex1 gene signature in breast cancer cells.
Barrio-Real L; Wertheimer E; Garg R; Abba MC; Kazanietz MG
Oncotarget; 2016 Aug; 7(32):51335-51348. PubMed ID: 27351228
[TBL] [Abstract][Full Text] [Related]
10. Rho GEFs and cancer: linking gene expression and metastatic dissemination.
Barrio-Real L; Kazanietz MG
Sci Signal; 2012 Oct; 5(244):pe43. PubMed ID: 23033535
[TBL] [Abstract][Full Text] [Related]
11. Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.
Sosa MS; Lopez-Haber C; Yang C; Wang H; Lemmon MA; Busillo JM; Luo J; Benovic JL; Klein-Szanto A; Yagi H; Gutkind JS; Parsons RE; Kazanietz MG
Mol Cell; 2010 Dec; 40(6):877-92. PubMed ID: 21172654
[TBL] [Abstract][Full Text] [Related]
12. CpG island shore methylation regulates caveolin-1 expression in breast cancer.
Rao X; Evans J; Chae H; Pilrose J; Kim S; Yan P; Huang RL; Lai HC; Lin H; Liu Y; Miller D; Rhee JK; Huang YW; Gu F; Gray JW; Huang TM; Nephew KP
Oncogene; 2013 Sep; 32(38):4519-28. PubMed ID: 23128390
[TBL] [Abstract][Full Text] [Related]
13. P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Paredes J; Albergaria A; Oliveira JT; Jerónimo C; Milanezi F; Schmitt FC
Clin Cancer Res; 2005 Aug; 11(16):5869-77. PubMed ID: 16115928
[TBL] [Abstract][Full Text] [Related]
14. ERK/MAPK Signaling Drives Overexpression of the Rac-GEF, PREX1, in BRAF- and NRAS-Mutant Melanoma.
Ryan MB; Finn AJ; Pedone KH; Thomas NE; Der CJ; Cox AD
Mol Cancer Res; 2016 Oct; 14(10):1009-1018. PubMed ID: 27418645
[TBL] [Abstract][Full Text] [Related]
15. NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer.
Liu M; Peng Y; Wang X; Guo Q; Shen S; Li G
BMC Cancer; 2010 Apr; 10():160. PubMed ID: 20423473
[TBL] [Abstract][Full Text] [Related]
16. Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.
Rubinstein JC; Tran N; Ma S; Halaban R; Krauthammer M
BMC Med Genomics; 2010 Feb; 3():4. PubMed ID: 20144234
[TBL] [Abstract][Full Text] [Related]
17. Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.
Bianco C; Castro NP; Baraty C; Rollman K; Held N; Rangel MC; Karasawa H; Gonzales M; Strizzi L; Salomon DS
J Cell Physiol; 2013 Jun; 228(6):1174-88. PubMed ID: 23129342
[TBL] [Abstract][Full Text] [Related]
18. Rac signaling in breast cancer: a tale of GEFs and GAPs.
Wertheimer E; Gutierrez-Uzquiza A; Rosemblit C; Lopez-Haber C; Sosa MS; Kazanietz MG
Cell Signal; 2012 Feb; 24(2):353-362. PubMed ID: 21893191
[TBL] [Abstract][Full Text] [Related]
19. Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.
Fujikane T; Nishikawa N; Toyota M; Suzuki H; Nojima M; Maruyama R; Ashida M; Ohe-Toyota M; Kai M; Nishidate T; Sasaki Y; Ohmura T; Hirata K; Tokino T
Breast Cancer Res Treat; 2010 Aug; 122(3):699-710. PubMed ID: 19859801
[TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.
Montero JC; Seoane S; Pandiella A
Cell Signal; 2013 Nov; 25(11):2281-9. PubMed ID: 23899556
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]