BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

374 related articles for article (PubMed ID: 25250570)

  • 1. IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.
    Garcia MN; Grasso D; Lopez-Millan MB; Hamidi T; Loncle C; Tomasini R; Lomberk G; Porteu F; Urrutia R; Iovanna JL
    J Clin Invest; 2014 Nov; 124(11):4709-22. PubMed ID: 25250570
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.
    He P; Yang JW; Yang VW; Bialkowska AB
    Gastroenterology; 2018 Apr; 154(5):1494-1508.e13. PubMed ID: 29248441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.
    Shi G; DiRenzo D; Qu C; Barney D; Miley D; Konieczny SF
    Oncogene; 2013 Apr; 32(15):1950-8. PubMed ID: 22665051
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-Catenin
    Gao C; Chen G; Zhang DH; Zhang J; Kuan SF; Hu W; Esni F; Gao X; Guan JL; Chu E; Hu J
    Cell Mol Gastroenterol Hepatol; 2019; 8(4):561-578. PubMed ID: 31330317
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases.
    Liou GY; Byrd CJ; Storz P; Messex JK
    Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38731942
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ANGPTL4 accelerates KRAS
    Yan HH; Jung KH; Lee JE; Son MK; Fang Z; Park JH; Kim SJ; Kim JY; Lim JH; Hong SS
    Cancer Lett; 2021 Oct; 519():185-198. PubMed ID: 34311032
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
    Nishikawa Y; Kodama Y; Shiokawa M; Matsumori T; Marui S; Kuriyama K; Kuwada T; Sogabe Y; Kakiuchi N; Tomono T; Mima A; Morita T; Ueda T; Tsuda M; Yamauchi Y; Sakuma Y; Ota Y; Maruno T; Uza N; Uesugi M; Kageyama R; Chiba T; Seno H
    Oncogene; 2019 May; 38(22):4283-4296. PubMed ID: 30705405
    [TBL] [Abstract][Full Text] [Related]  

  • 8. KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin.
    Shi C; Hong SM; Lim P; Kamiyama H; Khan M; Anders RA; Goggins M; Hruban RH; Eshleman JR
    Mol Cancer Res; 2009 Feb; 7(2):230-6. PubMed ID: 19208745
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.
    Shen R; Wang Q; Cheng S; Liu T; Jiang H; Zhu J; Wu Y; Wang L
    Cancer Lett; 2013 Oct; 339(1):135-43. PubMed ID: 23887057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis.
    Ge W; Goga A; He Y; Silva PN; Hirt CK; Herrmanns K; Guccini I; Godbersen S; Schwank G; Stoffel M
    Gastroenterology; 2022 Jan; 162(1):269-284. PubMed ID: 34547282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice.
    Bai H; Li H; Zhang W; Matkowskyj KA; Liao J; Srivastava SK; Yang GY
    Carcinogenesis; 2011 Nov; 32(11):1689-96. PubMed ID: 21859833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.
    Lee AYL; Dubois CL; Sarai K; Zarei S; Schaeffer DF; Sander M; Kopp JL
    Gut; 2019 Mar; 68(3):487-498. PubMed ID: 29363536
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Early requirement of Rac1 in a mouse model of pancreatic cancer.
    Heid I; Lubeseder-Martellato C; Sipos B; Mazur PK; Lesina M; Schmid RM; Siveke JT
    Gastroenterology; 2011 Aug; 141(2):719-30, 730.e1-7. PubMed ID: 21684285
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia.
    Ding L; Liou GY; Schmitt DM; Storz P; Zhang JS; Billadeau DD
    J Pathol; 2017 Sep; 243(1):65-77. PubMed ID: 28639695
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice.
    Johnson BL; d'Alincourt Salazar M; Mackenzie-Dyck S; D'Apuzzo M; Shih HP; Manuel ER; Diamond DJ
    PLoS One; 2019; 14(9):e0221810. PubMed ID: 31490946
    [TBL] [Abstract][Full Text] [Related]  

  • 17. YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.
    Gruber R; Panayiotou R; Nye E; Spencer-Dene B; Stamp G; Behrens A
    Gastroenterology; 2016 Sep; 151(3):526-39. PubMed ID: 27215660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
    Mazur PK; Einwächter H; Lee M; Sipos B; Nakhai H; Rad R; Zimber-Strobl U; Strobl LJ; Radtke F; Klöppel G; Schmid RM; Siveke JT
    Proc Natl Acad Sci U S A; 2010 Jul; 107(30):13438-43. PubMed ID: 20624967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Davies CC; Harvey E; McMahon RF; Finegan KG; Connor F; Davis RJ; Tuveson DA; Tournier C
    Cancer Res; 2014 Jun; 74(12):3344-56. PubMed ID: 24713432
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant
    Shen J; Ha DP; Zhu G; Rangel DF; Kobielak A; Gill PS; Groshen S; Dubeau L; Lee AS
    Proc Natl Acad Sci U S A; 2017 May; 114(20):E4020-E4029. PubMed ID: 28461470
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.