These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

390 related articles for article (PubMed ID: 25252616)

  • 1. Pregnane X receptor and drug-induced liver injury.
    Wang YM; Chai SC; Brewer CT; Chen T
    Expert Opin Drug Metab Toxicol; 2014 Nov; 10(11):1521-32. PubMed ID: 25252616
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PXR-mediated idiosyncratic drug-induced liver injury: mechanistic insights and targeting approaches.
    Wang J; Bwayi M; Gee RRF; Chen T
    Expert Opin Drug Metab Toxicol; 2020 Aug; 16(8):711-722. PubMed ID: 32500752
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the pregnane X receptor in liver injury.
    Li T; Yu RT; Atkins AR; Downes M; Tukey RH; Evans RM
    Expert Opin Ther Targets; 2012 Nov; 16(11):1075-83. PubMed ID: 22913318
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of CAR and PXR in xenobiotic sensing and metabolism.
    Wang YM; Ong SS; Chai SC; Chen T
    Expert Opin Drug Metab Toxicol; 2012 Jul; 8(7):803-17. PubMed ID: 22554043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pregnenolone 16α-carbonitrile ameliorates concanavalin A-induced liver injury in mice independent of the nuclear receptor PXR activation.
    Kodama S; Shimura T; Kuribayashi H; Abe T; Yoshinari K
    Toxicol Lett; 2017 Apr; 271():58-65. PubMed ID: 28237809
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Xenobiotic pregnane X receptor (PXR) regulates innate immunity via activation of NLRP3 inflammasome in vascular endothelial cells.
    Wang S; Lei T; Zhang K; Zhao W; Fang L; Lai B; Han J; Xiao L; Wang N
    J Biol Chem; 2014 Oct; 289(43):30075-81. PubMed ID: 25202020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A role for the pregnane X receptor in flucloxacillin-induced liver injury.
    Andrews E; Armstrong M; Tugwood J; Swan D; Glaves P; Pirmohamed M; Aithal GP; Wright MC; Day CP; Daly AK
    Hepatology; 2010 May; 51(5):1656-64. PubMed ID: 20222094
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pregnane X receptor mediated-transcription regulation of CYP3A by glycyrrhizin: a possible mechanism for its hepatoprotective property against lithocholic acid-induced injury.
    Wang YG; Zhou JM; Ma ZC; Li H; Liang QD; Tan HL; Xiao CR; Zhang BL; Gao Y
    Chem Biol Interact; 2012 Oct; 200(1):11-20. PubMed ID: 22982774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response.
    Pondugula SR; Mani S
    Cancer Lett; 2013 Jan; 328(1):1-9. PubMed ID: 22939994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of nuclear pregnane X receptor in Cu-induced lipid metabolism and xenobiotic responses in largemouth bass (
    Li H; Gong W; Wang G; Yu E; Tian J; Xia Y; Li Z; Zhang K; Xie J
    Front Endocrinol (Lausanne); 2022; 13():950985. PubMed ID: 35966089
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel functions of PXR in cardiometabolic disease.
    Zhou C
    Biochim Biophys Acta; 2016 Sep; 1859(9):1112-1120. PubMed ID: 26924429
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily.
    Smutny T; Mani S; Pavek P
    Curr Drug Metab; 2013 Dec; 14(10):1059-69. PubMed ID: 24329114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.
    Owen BM; Milona A; van Mil S; Clements P; Holder J; Boudjelal M; Cairns W; Parker M; White R; Williamson C
    Drug Metab Dispos; 2010 Jan; 38(1):143-9. PubMed ID: 19797606
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pregnane X Receptor and the Gut-Liver Axis: A Recent Update.
    Dutta M; Lim JJ; Cui JY
    Drug Metab Dispos; 2022 Apr; 50(4):478-491. PubMed ID: 34862253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).
    Bainy AC; Kubota A; Goldstone JV; Lille-Langøy R; Karchner SI; Celander MC; Hahn ME; Goksøyr A; Stegeman JJ
    Aquat Toxicol; 2013 Oct; 142-143():447-57. PubMed ID: 24121122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of PXR and CAR by protein-protein interaction and signaling crosstalk.
    Oladimeji P; Cui H; Zhang C; Chen T
    Expert Opin Drug Metab Toxicol; 2016 Sep; 12(9):997-1010. PubMed ID: 27295009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Xenobiotic Nuclear Receptors PXR and CAR to Prevent Cobicistat Hepatotoxicity.
    Shehu AI; Zhu J; Li J; Lu J; McMahon D; Xie W; Gonzalez FJ; Ma X
    Toxicol Sci; 2021 Apr; 181(1):58-67. PubMed ID: 33629115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epigenetic regulation of pregnane X receptor activity.
    Tian Y
    Drug Metab Rev; 2013 May; 45(2):166-72. PubMed ID: 23600685
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.