134 related articles for article (PubMed ID: 25253782)
1. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway.
Saito N; Sakakibara K; Sato T; Friedman JM; Kufe DW; VonHoff DD; Kawabe T
Mol Cancer Ther; 2014 Dec; 13(12):3013-23. PubMed ID: 25253782
[TBL] [Abstract][Full Text] [Related]
2. Novel reversible selective inhibitor of nuclear export shows that CRM1 is a target in colorectal cancer cells.
Niu M; Chong Y; Han Y; Liu X
Cancer Biol Ther; 2015; 16(7):1110-8. PubMed ID: 25996664
[TBL] [Abstract][Full Text] [Related]
3. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy.
Zhao Y; Morgan MA; Sun Y
Antioxid Redox Signal; 2014 Dec; 21(17):2383-400. PubMed ID: 24410571
[TBL] [Abstract][Full Text] [Related]
4. Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.
Liao H; Liu XJ; Blank JL; Bouck DC; Bernard H; Garcia K; Lightcap ES
Mol Cell Proteomics; 2011 Nov; 10(11):M111.009183. PubMed ID: 21873567
[TBL] [Abstract][Full Text] [Related]
5. Inhibitory effect of a neddylation blockade on HTLV-1-infected T cells
Ishikawa C; Mori N
Leuk Lymphoma; 2024 Mar; ():1-11. PubMed ID: 38489672
[TBL] [Abstract][Full Text] [Related]
6. The NEDD8 activating enzyme inhibitor MLN4924 mitigates doxorubicin-induced cardiotoxicity in mice.
Chen KH; Sun JM; Lin L; Liu JW; Liu XY; Chen GD; Chen H; Chen ZY
Free Radic Biol Med; 2024 Jul; 219():127-140. PubMed ID: 38614228
[TBL] [Abstract][Full Text] [Related]
7. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein.
Ortega JF; de Conti A; Tryndyak V; Furtado KS; Heidor R; Horst MA; Fernandes LH; Tavares PE; Pogribna M; Shpyleva S; Beland FA; Pogribny IP; Moreno FS
Oncotarget; 2016 Apr; 7(17):24339-47. PubMed ID: 27013579
[TBL] [Abstract][Full Text] [Related]
8. Jab1 as a mediator of nuclear export and cytoplasmic degradation of p53.
Lee EW; Oh W; Song J
Mol Cells; 2006 Oct; 22(2):133-40. PubMed ID: 17085963
[TBL] [Abstract][Full Text] [Related]
9. Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer.
Xu S; Ma Y; Tong Q; Yang J; Liu J; Wang Y; Li G; Zeng J; Fang S; Li F; Xie X; Zhang J
Cell Death Dis; 2021 Mar; 12(3):265. PubMed ID: 33712558
[TBL] [Abstract][Full Text] [Related]
10. Neddylation in the chronically hypoperfused corpus callosum: MLN4924 reduces blood-brain barrier injury via ERK5/KLF2 signaling.
Yang X; Chang L; Liu Z; Geng X; Wang R; Yin X; Fan W; Zhao BQ
Exp Neurol; 2024 Jan; 371():114587. PubMed ID: 37914067
[TBL] [Abstract][Full Text] [Related]
11. Identification of novel benzothiazole derivatives as inhibitors of NEDDylation pathway to inhibit the progression of gastric cancer.
Wang X; Zhao M; Chang Y; Guan S; Li M; Yang H; Sun M
Bioorg Med Chem Lett; 2024 Mar; 100():129647. PubMed ID: 38320715
[TBL] [Abstract][Full Text] [Related]
12. NNMT/1-MNA Promote Cell-Cycle Progression of Breast Cancer by Targeting UBC12/Cullin-1-Mediated Degradation of P27 Proteins.
Ma Y; Huang X; Wang Y; Lei Y; Yu J; Yu S; Gao Y; Yang J; Zhao F; Yu H; Zeng J; Chu Y; Yang M; Li G; Xie X; Zhang J
Adv Sci (Weinh); 2024 Mar; 11(9):e2305907. PubMed ID: 38126621
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.
Li Y; Shen S; Guo H; Li H; Zhang L; Zhang B; Yu XF; Wei W
Cell Rep; 2024 Feb; 43(2):113749. PubMed ID: 38329876
[TBL] [Abstract][Full Text] [Related]
14. Pharmacologic targeting of Nedd8-activating enzyme reinvigorates T-cell responses in lymphoid neoplasia.
Wang X; Chen C; Vuong D; Rodriguez-Rodriguez S; Lam V; Roleder C; Wang JH; Kambhampati S; Berger A; Pennock N; Torka P; Hernandez-Ilizaliturri F; Siddiqi T; Wang L; Xia Z; Danilov AV
Leukemia; 2023 Jun; 37(6):1324-1335. PubMed ID: 37031300
[TBL] [Abstract][Full Text] [Related]
15. The Role of Cullin-RING Ligases in Striated Muscle Development, Function, and Disease.
Blondelle J; Biju A; Lange S
Int J Mol Sci; 2020 Oct; 21(21):. PubMed ID: 33114658
[TBL] [Abstract][Full Text] [Related]
16. Proapoptotic effect of WS-299 induced by NOXA accumulation and NRF2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers.
Ma T; Song Q; Cheng B; Guo E; Wang X; Li M; Dai M; Li S; Feng S; Yu B
Bioorg Chem; 2024 Mar; 144():107142. PubMed ID: 38280358
[TBL] [Abstract][Full Text] [Related]
17. Advancements in colorectal cancer research: Unveiling the cellular and molecular mechanisms of neddylation (Review).
Wang T; Li X; Ma R; Sun J; Huang S; Sun Z; Wang M
Int J Oncol; 2024 Apr; 64(4):. PubMed ID: 38391033
[TBL] [Abstract][Full Text] [Related]
18. Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses.
Aubry A; Pearson JD; Charish J; Yu T; Sivak JM; Xirodimas DP; Avet-Loiseau H; Corre J; Monnier PP; Bremner R
Cell Rep; 2023 Aug; 42(8):112925. PubMed ID: 37552601
[TBL] [Abstract][Full Text] [Related]
19. Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy.
Zhang Q; Wu Q; Huan XJ; Song SS; Bao XB; Miao ZH; Wang YQ
Biochem Pharmacol; 2024 May; 223():116198. PubMed ID: 38588830
[TBL] [Abstract][Full Text] [Related]
20. Arctigenin impairs UBC12 enzyme activity and cullin neddylation to attenuate cancer cells.
Chen YF; Liu RZ; Ying WW; Yang YN; Xiang SF; Shao XJ; Cao J; Zhang YQ; Yang B; He QJ; Ying MD
Acta Pharmacol Sin; 2023 Mar; 44(3):661-669. PubMed ID: 36138144
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]