BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 25255315)

  • 1. Derlin-1 regulates mutant VCP-linked pathogenesis and endoplasmic reticulum stress-induced apoptosis.
    Liang CJ; Chang YC; Chang HC; Wang CK; Hung YC; Lin YE; Chan CC; Chen CH; Chang HY; Sang TK
    PLoS Genet; 2014 Sep; 10(9):e1004675. PubMed ID: 25255315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model.
    Chang YC; Hung WT; Chang YC; Chang HC; Wu CL; Chiang AS; Jackson GR; Sang TK
    PLoS Genet; 2011 Feb; 7(2):e1001288. PubMed ID: 21304887
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response.
    Wang T; Xu W; Qin M; Yang Y; Bao P; Shen F; Zhang Z; Xu J
    J Biol Chem; 2016 Jul; 291(27):14373-14384. PubMed ID: 27226613
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Derlin-1 and TER94/VCP/p97 are required for intestinal homeostasis.
    Liu F; Zhao H; Kong R; Shi L; Li Z; Ma R; Zhao H; Li Z
    J Genet Genomics; 2022 Mar; 49(3):195-207. PubMed ID: 34547438
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration.
    Higashiyama H; Hirose F; Yamaguchi M; Inoue YH; Fujikake N; Matsukage A; Kakizuka A
    Cell Death Differ; 2002 Mar; 9(3):264-73. PubMed ID: 11859409
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteomic analysis of a drosophila IBMPFD model reveals potential pathogenic mechanisms.
    Chan HT; Lee TR; Huang SH; Lee HY; Sang TK; Chan HL; Lyu PC
    Mol Biosyst; 2012 Jun; 8(6):1730-41. PubMed ID: 22481368
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.
    Ritson GP; Custer SK; Freibaum BD; Guinto JB; Geffel D; Moore J; Tang W; Winton MJ; Neumann M; Trojanowski JQ; Lee VM; Forman MS; Taylor JP
    J Neurosci; 2010 Jun; 30(22):7729-39. PubMed ID: 20519548
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pro178 and Pro183 of selenoprotein S are essential residues for interaction with p97(VCP) during endoplasmic reticulum-associated degradation.
    Lee JH; Kwon JH; Jeon YH; Ko KY; Lee SR; Kim IY
    J Biol Chem; 2014 May; 289(20):13758-68. PubMed ID: 24700463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting β-tubulin:CCT-β complexes incurs Hsp90- and VCP-related protein degradation and induces ER stress-associated apoptosis by triggering capacitative Ca2+ entry, mitochondrial perturbation and caspase overactivation.
    Lin YF; Lee YF; Liang PH
    Cell Death Dis; 2012 Nov; 3(11):e434. PubMed ID: 23190606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila.
    Griciuc A; Aron L; Roux MJ; Klein R; Giangrande A; Ueffing M
    PLoS Genet; 2010 Aug; 6(8):. PubMed ID: 20865169
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.
    Erzurumlu Y; Kose FA; Gozen O; Gozuacik D; Toth EA; Ballar P
    Int J Biochem Cell Biol; 2013 Apr; 45(4):773-82. PubMed ID: 23333620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants.
    Zhang T; Mishra P; Hay BA; Chan D; Guo M
    Elife; 2017 Mar; 6():. PubMed ID: 28322724
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease.
    Ren G; Tardi NJ; Matsuda F; Koh KH; Ruiz P; Wei C; Altintas MM; Ploegh H; Reiser J
    Am J Physiol Renal Physiol; 2018 Mar; 314(3):F471-F482. PubMed ID: 29167172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.
    Johnson AE; Orr BO; Fetter RD; Moughamian AJ; Primeaux LA; Geier EG; Yokoyama JS; Miller BL; Davis GW
    Nat Commun; 2021 Jan; 12(1):513. PubMed ID: 33479240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.
    Weihl CC; Dalal S; Pestronk A; Hanson PI
    Hum Mol Genet; 2006 Jan; 15(2):189-99. PubMed ID: 16321991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of Cdc48/VCP-mediated cell death: from yeast apoptosis to human disease.
    Braun RJ; Zischka H
    Biochim Biophys Acta; 2008 Jul; 1783(7):1418-35. PubMed ID: 18284922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration.
    Poksay KS; Madden DT; Peter AK; Niazi K; Banwait S; Crippen D; Bredesen DE; Rao RV
    J Mol Neurosci; 2011 Jun; 44(2):91-102. PubMed ID: 21249466
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the Drosophila atlastin interactome reveals VCP as a functionally related interactor.
    O'Sullivan NC; Dräger N; O'Kane CJ
    J Genet Genomics; 2013 Jun; 40(6):297-306. PubMed ID: 23790629
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
    Custer SK; Neumann M; Lu H; Wright AC; Taylor JP
    Hum Mol Genet; 2010 May; 19(9):1741-55. PubMed ID: 20147319
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATPase activity of p97/valosin-containing protein is regulated by oxidative modification of the evolutionally conserved cysteine 522 residue in Walker A motif.
    Noguchi M; Takata T; Kimura Y; Manno A; Murakami K; Koike M; Ohizumi H; Hori S; Kakizuka A
    J Biol Chem; 2005 Dec; 280(50):41332-41. PubMed ID: 16234241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.