These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 25256246)

  • 1. A fluorimetric readout reporting the kinetics of nucleotide-induced human ribonucleotide reductase oligomerization.
    Fu Y; Lin H; Wisitpitthaya S; Blessing WA; Aye Y
    Chembiochem; 2014 Nov; 15(17):2598-2604. PubMed ID: 25256246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers.
    Aye Y; Brignole EJ; Long MJ; Chittuluru J; Drennan CL; Asturias FJ; Stubbe J
    Chem Biol; 2012 Jul; 19(7):799-805. PubMed ID: 22840768
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Uncoupling of allosteric and oligomeric regulation in a functional hybrid enzyme constructed from Escherichia coli and human ribonucleotide reductase.
    Fu Y; Long MJ; Rigney M; Parvez S; Blessing WA; Aye Y
    Biochemistry; 2013 Oct; 52(40):7050-9. PubMed ID: 24024562
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit.
    Aye Y; Stubbe J
    Proc Natl Acad Sci U S A; 2011 Jun; 108(24):9815-20. PubMed ID: 21628579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
    Fairman JW; Wijerathna SR; Ahmad MF; Xu H; Nakano R; Jha S; Prendergast J; Welin RM; Flodin S; Roos A; Nordlund P; Li Z; Walz T; Dealwis CG
    Nat Struct Mol Biol; 2011 Mar; 18(3):316-22. PubMed ID: 21336276
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of an oligomeric interface prevents allosteric inhibition of
    Chen PY; Funk MA; Brignole EJ; Drennan CL
    J Biol Chem; 2018 Jun; 293(26):10404-10412. PubMed ID: 29700111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diversity in Overall Activity Regulation of Ribonucleotide Reductase.
    Jonna VR; Crona M; Rofougaran R; Lundin D; Johansson S; Brännström K; Sjöberg BM; Hofer A
    J Biol Chem; 2015 Jul; 290(28):17339-48. PubMed ID: 25971975
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A glutaredoxin domain fused to the radical-generating subunit of ribonucleotide reductase (RNR) functions as an efficient RNR reductant.
    Rozman Grinberg I; Lundin D; Sahlin M; Crona M; Berggren G; Hofer A; Sjöberg BM
    J Biol Chem; 2018 Oct; 293(41):15889-15900. PubMed ID: 30166338
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.
    Bimai O; Banerjee I; Rozman Grinberg I; Huang P; Hultgren L; Ekström S; Lundin D; Sjöberg BM; Logan DT
    Elife; 2024 Jul; 12():. PubMed ID: 38968292
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An endogenous dAMP ligand in
    Parker MJ; Maggiolo AO; Thomas WC; Kim A; Meisburger SP; Ando N; Boal AK; Stubbe J
    Proc Natl Acad Sci U S A; 2018 May; 115(20):E4594-E4603. PubMed ID: 29712847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.
    Ando N; Li H; Brignole EJ; Thompson S; McLaughlin MI; Page JE; Asturias FJ; Stubbe J; Drennan CL
    Biochemistry; 2016 Jan; 55(2):373-81. PubMed ID: 26727048
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for genetically independent allosteric regulatory domains of the protein M1 subunit of mouse ribonucleotide reductase.
    Eriksson S; Gudas LJ; Clift SM; Caras IW; Ullman B; Martin DW
    J Biol Chem; 1981 Oct; 256(19):10193-7. PubMed ID: 7024267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric regulation of the class III anaerobic ribonucleotide reductase from bacteriophage T4.
    Andersson J; Westman M; Hofer A; Sjoberg BM
    J Biol Chem; 2000 Jun; 275(26):19443-8. PubMed ID: 10748029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cross-talk between the allosteric effector-binding sites in mouse ribonucleotide reductase.
    Reichard P; Eliasson R; Ingemarson R; Thelander L
    J Biol Chem; 2000 Oct; 275(42):33021-6. PubMed ID: 10884394
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors.
    Uppsten M; Färnegårdh M; Jordan A; Eliasson R; Eklund H; Uhlin U
    J Mol Biol; 2003 Jun; 330(1):87-97. PubMed ID: 12818204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IRBIT promotes allosteric inhibition of ribonucleotide reductase.
    Cancer Discov; 2014 Nov; 4(11):1255. PubMed ID: 25367944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancement by effectors and substrate nucleotides of R1-R2 interactions in Escherichia coli class Ia ribonucleotide reductase.
    Kasrayan A; Birgander PL; Pappalardo L; Regnström K; Westman M; Slaby A; Gordon E; Sjöberg BM
    J Biol Chem; 2004 Jul; 279(30):31050-7. PubMed ID: 15145955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Basis of dATP inhibition of RNRs.
    Greene BL; Nocera DG; Stubbe J
    J Biol Chem; 2018 Jun; 293(26):10413-10414. PubMed ID: 29959279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An ultrafiltration assay for nucleotide binding to ribonucleotide reductase.
    Ormö M; Sjöberg BM
    Anal Biochem; 1990 Aug; 189(1):138-41. PubMed ID: 2278383
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enzyme regulation. IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes.
    Arnaoutov A; Dasso M
    Science; 2014 Sep; 345(6203):1512-5. PubMed ID: 25237103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.