300 related articles for article (PubMed ID: 25261239)
1. A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer.
Fujimura K; Wright T; Strnadel J; Kaushal S; Metildi C; Lowy AM; Bouvet M; Kelber JA; Klemke RL
Cancer Res; 2014 Nov; 74(22):6671-81. PubMed ID: 25261239
[TBL] [Abstract][Full Text] [Related]
2. KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop.
Fujimura K; Wang H; Watson F; Klemke RL
Cancer Res; 2018 Mar; 78(6):1444-1456. PubMed ID: 29321164
[TBL] [Abstract][Full Text] [Related]
3. eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth.
Strnadel J; Choi S; Fujimura K; Wang H; Zhang W; Wyse M; Wright T; Gross E; Peinado C; Park HW; Bui J; Kelber J; Bouvet M; Guan KL; Klemke RL
Cancer Res; 2017 Apr; 77(8):1997-2007. PubMed ID: 28381547
[TBL] [Abstract][Full Text] [Related]
4. Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Coni S; Serrao SM; Yurtsever ZN; Di Magno L; Bordone R; Bertani C; Licursi V; Ianniello Z; Infante P; Moretti M; Petroni M; Guerrieri F; Fatica A; Macone A; De Smaele E; Di Marcotullio L; Giannini G; Maroder M; Agostinelli E; Canettieri G
Cell Death Dis; 2020 Dec; 11(12):1045. PubMed ID: 33303756
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A.
Hoque M; Hanauske-Abel HM; Palumbo P; Saxena D; D'Alliessi Gandolfi D; Park MH; Pe'ery T; Mathews MB
Retrovirology; 2009 Oct; 6():90. PubMed ID: 19825182
[TBL] [Abstract][Full Text] [Related]
6. Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment.
Park MH; Kar RK; Banka S; Ziegler A; Chung WK
Amino Acids; 2022 Apr; 54(4):485-499. PubMed ID: 34273022
[TBL] [Abstract][Full Text] [Related]
7. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels.
Fujimura K; Choi S; Wyse M; Strnadel J; Wright T; Klemke R
J Biol Chem; 2015 Dec; 290(50):29907-19. PubMed ID: 26483550
[TBL] [Abstract][Full Text] [Related]
8. Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder.
Ganapathi M; Padgett LR; Yamada K; Devinsky O; Willaert R; Person R; Au PB; Tagoe J; McDonald M; Karlowicz D; Wolf B; Lee J; Shen Y; Okur V; Deng L; LeDuc CA; Wang J; Hanner A; Mirmira RG; Park MH; Mastracci TL; Chung WK
Am J Hum Genet; 2019 Feb; 104(2):287-298. PubMed ID: 30661771
[TBL] [Abstract][Full Text] [Related]
9. Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.
McDonald PC; Chafe SC; Brown WS; Saberi S; Swayampakula M; Venkateswaran G; Nemirovsky O; Gillespie JA; Karasinska JM; Kalloger SE; Supuran CT; Schaeffer DF; Bashashati A; Shah SP; Topham JT; Yapp DT; Li J; Renouf DJ; Stanger BZ; Dedhar S
Gastroenterology; 2019 Sep; 157(3):823-837. PubMed ID: 31078621
[TBL] [Abstract][Full Text] [Related]
10. Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation.
Mémin E; Hoque M; Jain MR; Heller DS; Li H; Cracchiolo B; Hanauske-Abel HM; Pe'ery T; Mathews MB
Cancer Res; 2014 Jan; 74(2):552-62. PubMed ID: 24220243
[TBL] [Abstract][Full Text] [Related]
11. Bi-allelic variants in DOHH, catalyzing the last step of hypusine biosynthesis, are associated with a neurodevelopmental disorder.
Ziegler A; Steindl K; Hanner AS; Kar RK; Prouteau C; Boland A; Deleuze JF; Coubes C; Bézieau S; Küry S; Maystadt I; Le Mao M; Lenaers G; Navet B; Faivre L; Tran Mau-Them F; Zanoni P; Chung WK; Rauch A; Bonneau D; Park MH
Am J Hum Genet; 2022 Aug; 109(8):1549-1558. PubMed ID: 35858628
[TBL] [Abstract][Full Text] [Related]
12. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
Wolff EC; Kang KR; Kim YS; Park MH
Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
[TBL] [Abstract][Full Text] [Related]
13. Translation Factor eIF5A, Modification with Hypusine and Role in Regulation of Gene Expression. eIF5A as a Target for Pharmacological Interventions.
Turpaev KT
Biochemistry (Mosc); 2018 Aug; 83(8):863-873. PubMed ID: 30208826
[TBL] [Abstract][Full Text] [Related]
14. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation.
Park MH; Wolff EC
J Biol Chem; 2018 Nov; 293(48):18710-18718. PubMed ID: 30257869
[TBL] [Abstract][Full Text] [Related]
15. Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.
Nishimura K; Lee SB; Park JH; Park MH
Amino Acids; 2012 Feb; 42(2-3):703-10. PubMed ID: 21850436
[TBL] [Abstract][Full Text] [Related]
16. Functional significance of eIF5A and its hypusine modification in eukaryotes.
Park MH; Nishimura K; Zanelli CF; Valentini SR
Amino Acids; 2010 Feb; 38(2):491-500. PubMed ID: 19997760
[TBL] [Abstract][Full Text] [Related]
17. Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.
Kar RK; Hanner AS; Starost MF; Springer D; Mastracci TL; Mirmira RG; Park MH
J Biol Chem; 2021 Nov; 297(5):101333. PubMed ID: 34688659
[TBL] [Abstract][Full Text] [Related]
18. Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
Nagathihalli NS; Castellanos JA; Shi C; Beesetty Y; Reyzer ML; Caprioli R; Chen X; Walsh AJ; Skala MC; Moses HL; Merchant NB
Gastroenterology; 2015 Dec; 149(7):1932-1943.e9. PubMed ID: 26255562
[TBL] [Abstract][Full Text] [Related]
19. Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.
Nakanishi S; Cleveland JL
Amino Acids; 2016 Oct; 48(10):2353-62. PubMed ID: 27357307
[TBL] [Abstract][Full Text] [Related]
20. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
Park JH; Dias CA; Lee SB; Valentini SR; Sokabe M; Fraser CS; Park MH
Protein Eng Des Sel; 2011 Mar; 24(3):301-9. PubMed ID: 21131325
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]