These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 25261239)

  • 21. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
    Park JH; Dias CA; Lee SB; Valentini SR; Sokabe M; Fraser CS; Park MH
    Protein Eng Des Sel; 2011 Mar; 24(3):301-9. PubMed ID: 21131325
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
    Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
    [TBL] [Abstract][Full Text] [Related]  

  • 23. EIF5A regulates proliferation and chemoresistance in pancreatic cancer through the sHH signalling pathway.
    Wang Z; Jiang J; Qin T; Xiao Y; Han L
    J Cell Mol Med; 2019 Apr; 23(4):2678-2688. PubMed ID: 30761741
    [TBL] [Abstract][Full Text] [Related]  

  • 24. KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.
    Kelber JA; Reno T; Kaushal S; Metildi C; Wright T; Stoletov K; Weems JM; Park FD; Mose E; Wang Y; Hoffman RM; Lowy AM; Bouvet M; Klemke RL
    Cancer Res; 2012 May; 72(10):2554-64. PubMed ID: 22589274
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A.
    Kang KR; Kim YS; Wolff EC; Park MH
    J Biol Chem; 2007 Mar; 282(11):8300-8. PubMed ID: 17213197
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The role of eukaryotic translation initiation factor 5A-1 (eIF5A-1) gene in HPV 16 E6 induces cell growth in human cervical squamous carcinoma cells.
    Liu Z; Teng L; Gao L; Wang H; Su Y; Li J
    Biochem Biophys Res Commun; 2018 Sep; 504(1):6-12. PubMed ID: 30170728
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Precise and efficient silencing of mutant Kras
    Jiang W; Li H; Liu X; Zhang J; Zhang W; Li T; Liu L; Yu X
    Theranostics; 2020; 10(25):11507-11519. PubMed ID: 33052229
    [No Abstract]   [Full Text] [Related]  

  • 28. A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.
    Ocal O; Pashkov V; Kollipara RK; Zolghadri Y; Cruz VH; Hale MA; Heath BR; Artyukhin AB; Christie AL; Tsoulfas P; Lorens JB; Swift GH; Brekken RA; Wilkie TM
    Dis Model Mech; 2015 Oct; 8(10):1201-11. PubMed ID: 26438693
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Targeting deoxyhypusine hydroxylase activity impairs cap-independent translation initiation driven by the 5'untranslated region of the HIV-1, HTLV-1, and MMTV mRNAs.
    Cáceres CJ; Angulo J; Contreras N; Pino K; Vera-Otarola J; López-Lastra M
    Antiviral Res; 2016 Oct; 134():192-206. PubMed ID: 27633452
    [TBL] [Abstract][Full Text] [Related]  

  • 30. SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells.
    Wuebben EL; Wilder PJ; Cox JL; Grunkemeyer JA; Caffrey T; Hollingsworth MA; Rizzino A
    Oncotarget; 2016 Jun; 7(23):34890-906. PubMed ID: 27145457
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma.
    Lee NP; Tsang FH; Shek FH; Mao M; Dai H; Zhang C; Dong S; Guan XY; Poon RT; Luk JM
    Int J Cancer; 2010 Aug; 127(4):968-76. PubMed ID: 19998337
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
    Park MH
    J Biochem; 2006 Feb; 139(2):161-9. PubMed ID: 16452303
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Eukaryotic translation initiation factor 5A and its posttranslational modifications play an important role in proliferation and potentially in differentiation of the human enteric protozoan parasite Entamoeba histolytica.
    Jeelani G; Nozaki T
    PLoS Pathog; 2021 Feb; 17(2):e1008909. PubMed ID: 33592076
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The translation factor eIF5A and human cancer.
    Mathews MB; Hershey JW
    Biochim Biophys Acta; 2015 Jul; 1849(7):836-44. PubMed ID: 25979826
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development.
    Padgett LR; Robertson MA; Anderson-Baucum EK; Connors CT; Wu W; Mirmira RG; Mastracci TL
    FASEB J; 2021 May; 35(5):e21473. PubMed ID: 33811703
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.
    Patel PH; Costa-Mattioli M; Schulze KL; Bellen HJ
    J Cell Biol; 2009 Jun; 185(7):1181-94. PubMed ID: 19546244
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Oncogenic ERBB2 aberrations and KRAS mutations cooperate to promote pancreatic ductal adenocarcinoma progression.
    Li Z; Shao C; Liu X; Lu X; Jia X; Zheng X; Wang S; Zhu L; Li K; Pang Y; Xie F; Lu Y; Wang Y
    Carcinogenesis; 2020 Mar; 41(1):44-55. PubMed ID: 31046123
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.
    Nagathihalli NS; Castellanos JA; Lamichhane P; Messaggio F; Shi C; Dai X; Rai P; Chen X; VanSaun MN; Merchant NB
    Cancer Res; 2018 Nov; 78(21):6235-6246. PubMed ID: 30154150
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells.
    Xu D; Allsop SA; Witherspoon SM; Snider JL; Yeh JJ; Fiordalisi JJ; White CD; Williams D; Cox AD; Baines AT
    Carcinogenesis; 2011 Apr; 32(4):488-95. PubMed ID: 21262926
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.
    Maier B; Ogihara T; Trace AP; Tersey SA; Robbins RD; Chakrabarti SK; Nunemaker CS; Stull ND; Taylor CA; Thompson JE; Dondero RS; Lewis EC; Dinarello CA; Nadler JL; Mirmira RG
    J Clin Invest; 2010 Jun; 120(6):2156-70. PubMed ID: 20501948
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.