These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

649 related articles for article (PubMed ID: 25263562)

  • 21. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.
    Deng L; Jiang C; Chen L; Jin J; Wei J; Zhao L; Chen M; Pan W; Xu Y; Chu H; Wang X; Ge X; Li D; Liao L; Liu M; Li L; Wang P
    Mol Cell; 2015 Jun; 58(5):804-18. PubMed ID: 25936802
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation.
    Kimball SR; Gordon BS; Moyer JE; Dennis MD; Jefferson LS
    Cell Signal; 2016 Aug; 28(8):896-906. PubMed ID: 27010498
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function.
    Cai W; Wei Y; Jarnik M; Reich J; Lilly MA
    PLoS Genet; 2016 May; 12(5):e1006036. PubMed ID: 27166823
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Rag GTPase in amino acid signaling.
    Kim J; Kim E
    Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
    [TBL] [Abstract][Full Text] [Related]  

  • 25. RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
    Sekiguchi T; Furuno N; Ishii T; Hirose E; Sekiguchi F; Wang Y; Kobayashi H
    Genes Cells; 2019 Feb; 24(2):151-161. PubMed ID: 30570184
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Effects of Leucine Ingestion and Contraction on the Sestrin/GATOR2 Pathway and mTORC1 Activation in Rat Fast-Twitch muscle.
    Kanzaki K; Wada M
    J Nutr; 2023 Aug; 153(8):2228-2236. PubMed ID: 37328110
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition.
    Figlia G; Müller S; Hagenston AM; Kleber S; Roiuk M; Quast JP; Ten Bosch N; Carvajal Ibañez D; Mauceri D; Martin-Villalba A; Teleman AA
    Nat Cell Biol; 2022 Sep; 24(9):1407-1421. PubMed ID: 36097071
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
    Chantranupong L; Scaria SM; Saxton RA; Gygi MP; Shen K; Wyant GA; Wang T; Harper JW; Gygi SP; Sabatini DM
    Cell; 2016 Mar; 165(1):153-164. PubMed ID: 26972053
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.
    Doxsey DD; Tettoni SD; Egri SB; Shen K
    J Biol Chem; 2023 Jul; 299(7):104880. PubMed ID: 37269949
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
    Jin G; Lee SW; Zhang X; Cai Z; Gao Y; Chou PC; Rezaeian AH; Han F; Wang CY; Yao JC; Gong Z; Chan CH; Huang CY; Tsai FJ; Tsai CH; Tu SH; Wu CH; Sarbassov dos D; Ho YS; Lin HK
    Mol Cell; 2015 Jun; 58(6):989-1000. PubMed ID: 26051179
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
    Saxton RA; Chantranupong L; Knockenhauer KE; Schwartz TU; Sabatini DM
    Nature; 2016 Aug; 536(7615):229-33. PubMed ID: 27487210
    [TBL] [Abstract][Full Text] [Related]  

  • 32. GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2.
    Ye J; Palm W; Peng M; King B; Lindsten T; Li MO; Koumenis C; Thompson CB
    Genes Dev; 2015 Nov; 29(22):2331-6. PubMed ID: 26543160
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
    Yan G; Yang J; Li W; Guo A; Guan J; Liu Y
    Nat Cell Biol; 2023 May; 25(5):754-764. PubMed ID: 37037994
    [TBL] [Abstract][Full Text] [Related]  

  • 34. New insights into GATOR2-dependent interactions and its conformational changes in amino acid sensing.
    Yang C; Sun X; Wu G
    Biosci Rep; 2024 Mar; 44(3):. PubMed ID: 38372438
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Wdr59 promotes or inhibits TORC1 activity depending on cellular context.
    Zhang Y; Ting CY; Yang S; Reich J; Fru K; Lilly MA
    Proc Natl Acad Sci U S A; 2023 Jan; 120(1):e2212330120. PubMed ID: 36577058
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Regulation of mTORC1 by amino acids.
    Bar-Peled L; Sabatini DM
    Trends Cell Biol; 2014 Jul; 24(7):400-6. PubMed ID: 24698685
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
    Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
    Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
    Shen K; Valenstein ML; Gu X; Sabatini DM
    J Biol Chem; 2019 Feb; 294(8):2970-2975. PubMed ID: 30651352
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A multiprotein complex negatively regulates RAG GTPases and mTORC1.
    Cancer Discov; 2013 Jul; 3(7):OF24. PubMed ID: 23847368
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.
    Kwak SS; Kang KH; Kim S; Lee S; Lee JH; Kim JW; Byun B; Meadows GG; Joe CO
    Cell Signal; 2016 Feb; 28(2):32-41. PubMed ID: 26582740
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 33.