These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 25266781)

  • 1. Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
    Desrat S; Pujals A; Colas C; Dardenne J; Gény C; Favre L; Dumontet V; Iorga BI; Litaudon M; Raphaël M; Wiels J; Roussi F
    Bioorg Med Chem Lett; 2014 Nov; 24(21):5086-8. PubMed ID: 25266781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of an efficient route toward meiogynin A-inspired dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins.
    Desrat S; Remeur C; Roussi F
    Org Biomol Chem; 2015 May; 13(19):5520-31. PubMed ID: 25877523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins.
    Desrat S; Remeur C; Gény C; Rivière G; Colas C; Dumontet V; Birlirakis N; Iorga BI; Roussi F
    Chem Commun (Camb); 2014 Aug; 50(62):8593-6. PubMed ID: 24956071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biomimetic total synthesis of meiogynin A, an inhibitor of Bcl-xL and Bak interaction.
    Fotsop DF; Roussi F; Leverrier A; Bretéché A; Guéritte F
    J Org Chem; 2010 Nov; 75(21):7412-5. PubMed ID: 20929197
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak.
    Cao X; Yap JL; Newell-Rogers MK; Peddaboina C; Jiang W; Papaconstantinou HT; Jupitor D; Rai A; Jung KY; Tubin RP; Yu W; Vanommeslaeghe K; Wilder PT; MacKerell AD; Fletcher S; Smythe RW
    Mol Cancer; 2013 May; 12(1):42. PubMed ID: 23680104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A.
    Abou Samra A; Robert A; Gov C; Favre L; Eloy L; Jacquet E; Bignon J; Wiels J; Desrat S; Roussi F
    Eur J Med Chem; 2018 Mar; 148():26-38. PubMed ID: 29453135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.
    Li R; Cheng C; Balasis ME; Liu Y; Garner TP; Daniel KG; Li J; Qin Y; Gavathiotis E; Sebti SM
    Eur J Med Chem; 2015 Jan; 90():315-331. PubMed ID: 25437618
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X
    Greaves G; Milani M; Butterworth M; Carter RJ; Byrne DP; Eyers PA; Luo X; Cohen GM; Varadarajan S
    Cell Death Differ; 2019 Jun; 26(6):1037-1047. PubMed ID: 30185825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
    Gény C; Rivière G; Bignon J; Birlirakis N; Guittet E; Awang K; Litaudon M; Roussi F; Dumontet V
    J Nat Prod; 2016 Apr; 79(4):838-44. PubMed ID: 27008174
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells.
    Doi K; Gowda K; Liu Q; Lin JM; Sung SS; Dower C; Claxton D; Loughran TP; Amin S; Wang HG
    Cancer Biol Ther; 2014; 15(12):1688-99. PubMed ID: 25535900
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak.
    Sun JG; Xiang J; Zeng XL; Li X; Wu P; Fung KP; Liu FY
    Cancer Lett; 2014 Dec; 355(2):253-63. PubMed ID: 25304383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Computational Design of BH3-Mimetic Peptide Inhibitors That Can Bind Specifically to Mcl-1 or Bcl-X
    Reddy CN; Manzar N; Ateeq B; Sankararamakrishnan R
    Biochemistry; 2020 Nov; 59(45):4379-4394. PubMed ID: 33146015
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of HA14-1 on apoptosis-regulating proteins in HeLa cells.
    Rehman K; Tariq M; Akash MS; Gillani Z; Qazi MH
    Chem Biol Drug Des; 2014 Mar; 83(3):317-23. PubMed ID: 24118733
    [TBL] [Abstract][Full Text] [Related]  

  • 14. De novo design, synthesis and evaluation of benzylpiperazine derivatives as highly selective binders of Mcl-1.
    Ding X; Li Y; Lv L; Zhou M; Han L; Zhang Z; Ba Q; Li J; Wang H; Liu H; Wang R
    ChemMedChem; 2013 Dec; 8(12):1986-2014. PubMed ID: 24124106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. First evidence that oligopyridines, α-helix foldamers, inhibit Mcl-1 and sensitize ovarian carcinoma cells to Bcl-xL-targeting strategies.
    Gloaguen C; Voisin-Chiret AS; Sopkova-de Oliveira Santos J; Fogha J; Gautier F; De Giorgi M; Burzicki G; Perato S; Pétigny-Lechartier C; Simonin-Le Jeune K; Brotin E; Goux D; N'Diaye M; Lambert B; Louis MH; Ligat L; Lopez F; Juin P; Bureau R; Rault S; Poulain L
    J Med Chem; 2015 Feb; 58(4):1644-68. PubMed ID: 25585174
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
    Zhu HB; Huang XF; Hu JZ; Zhou W; Chen W; Chen LL; He C
    Zhonghua Zhong Liu Za Zhi; 2008 Apr; 30(4):245-9. PubMed ID: 18788624
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.
    Timme CR; Gruidl M; Yeatman TJ
    Apoptosis; 2013 Oct; 18(10):1163-74. PubMed ID: 23887890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on celecoxib-induced apoptosis.
    Rudner J; Elsaesser SJ; Müller AC; Belka C; Jendrossek V
    Biochem Pharmacol; 2010 Jan; 79(1):10-20. PubMed ID: 19665451
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pan-BH3 mimetic S1 exhibits broad-spectrum antitumour effects by cooperation between Bax and Bak.
    Song T; Xue Z; Zhang Z; Shen X; Li X
    Basic Clin Pharmacol Toxicol; 2013 Sep; 113(3):145-51. PubMed ID: 23557083
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heptaphylline induces apoptosis in human colon adenocarcinoma cells through bid and Akt/NF-κB (p65) pathways.
    Boonyarat C; Yenjai C; Vajragupta O; Waiwut P
    Asian Pac J Cancer Prev; 2014; 15(23):10483-7. PubMed ID: 25556496
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.