BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 2526736)

  • 1. Sequence-dependent enhancement of HCT-8 cell kill by trimetrexate and fluoropyrimidines: implications for the mechanism of this interaction.
    Sobrero A; Romanini A; Russello O; Nicolin A; Rosso R; Bertino JR
    Eur J Cancer Clin Oncol; 1989 Jun; 25(6):977-82. PubMed ID: 2526736
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Implications for improved high-dose methotrexate therapeutic effects in cultured human breast cancer and bone marrow cells.
    Bowen D; Southerland WM; Johnson DH; Hawkins M; Hughes DE
    Cancer Detect Prev; 2000; 24(5):452-8. PubMed ID: 11129987
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of 5-methyltetrahydrofolate on the activity of fluoropyrimidines against human leukemia (CCRF-CEM) cells.
    Mini E; Mazzei T; Coronnello M; Criscuoli L; Gualtieri M; Periti P; Bertino JR
    Biochem Pharmacol; 1987 Sep; 36(18):2905-11. PubMed ID: 2958010
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil, in CCRF-CEM cells.
    Romanini A; Li WW; Colofiore JR; Bertino JR
    J Natl Cancer Inst; 1992 Jul; 84(13):1033-8. PubMed ID: 1376779
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequence and schedule-dependent synergy of trimetrexate in combination with 5-fluorouracil in vitro and in mice.
    Elliott WL; Howard CT; Dykes DJ; Leopold WR
    Cancer Res; 1989 Oct; 49(20):5586-90. PubMed ID: 2477146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.
    Zhang ZG; Malmberg M; Yin MB; Slocum HK; Rustum YM
    Biochem Pharmacol; 1993 Mar; 45(5):1157-64. PubMed ID: 8461045
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
    Allegra CJ; Hoang K; Yeh GC; Drake JC; Baram J
    J Biol Chem; 1987 Oct; 262(28):13520-6. PubMed ID: 2443493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Schedule-dependent synergism and antagonism between raltitrexed ("Tomudex") and methotrexate in human colon cancer cell lines in vitro.
    Kano Y; Akutsu M; Tsunoda S; Suzuki K; Yazawa Y; Furukawa Y
    Jpn J Cancer Res; 2001 Jan; 92(1):74-82. PubMed ID: 11173547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative DNA strand breakage induced by FUra and FdUrd in human ileocecal adenocarcinoma (HCT-8) cells: relevance to cell growth inhibition.
    Yin MB; Rustum YM
    Cancer Commun; 1991 Feb; 3(2):45-51. PubMed ID: 1825284
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancement of fluoropyrimidine cytotoxicity by 5-methyltetrahydrofolate in a human leukemia cell line, CCRF-CEM.
    Mini E; Mazzei T; Coronnello M; Criscuoli L; Gualtieri M; Periti P
    Chemioterapia; 1985 Dec; 4(6):454-9. PubMed ID: 2937563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG2034): comparison across sensitive and resistant human tumor cell lines.
    Faessel HM; Slocum HK; Rustum YM; Greco WR
    Biochem Pharmacol; 1999 Mar; 57(5):567-77. PubMed ID: 9952321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic efficacy of fluoropyrimidines depends on the duration of thymidylate synthase inhibition in the murine colon 26-B carcinoma tumor model.
    van Laar JA; van der Wilt CL; Rustum YM; Noordhuis P; Smid K; Pinedo HM; Peters GJ
    Clin Cancer Res; 1996 Aug; 2(8):1327-33. PubMed ID: 9816304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pretreatment of colon carcinoma cells with Tomudex enhances 5-fluorouracil cytotoxicity.
    Longo GS; Izzo J; Chang YM; Tong WP; Zielinski Z; Gorlick R; Chou TC; Bertino JR
    Clin Cancer Res; 1998 Feb; 4(2):469-73. PubMed ID: 9516938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapid development of resistance to antifolates in vitro: possible clinical implication.
    Sobrero A; Aschele C; Rosso R; Nicolin A; Bertino JR
    J Natl Cancer Inst; 1991 Jan; 83(1):24-8. PubMed ID: 1824599
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence dependent synergistic cytotoxicity between etoposide and fluoropyrimidines.
    Damon LE; Christensen S; Rochlitz C; Cadman EC
    Anticancer Res; 1989; 9(6):1761-7. PubMed ID: 2534035
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H; Takemura Y; Kobayashi H; Ando Y
    Jpn J Cancer Res; 1997 Sep; 88(9):900-6. PubMed ID: 9369939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antifolate drug interactions: enhancement of growth inhibition due to the antipurine 5,10-dideazatetrahydrofolic acid by the lipophilic dihydrofolate reductase inhibitors metoprine and trimetrexate.
    Galivan J; Nimec Z; Rhee M; Boschelli D; Oronsky AL; Kerwar SS
    Cancer Res; 1988 May; 48(9):2421-5. PubMed ID: 2965613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biomodulation of 5-fluorouracil with antifolates.
    Bertino JR
    Semin Oncol; 1997 Oct; 24(5 Suppl 18):S18-52-S18-56. PubMed ID: 9420021
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
    Pizzorno G; Chang YM; McGuire JJ; Bertino JR
    Cancer Res; 1989 Oct; 49(19):5275-80. PubMed ID: 2475246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
    Galivan J; Nimec Z; Rhee M
    Cancer Res; 1987 Oct; 47(20):5256-60. PubMed ID: 2958130
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.