135 related articles for article (PubMed ID: 2526736)
1. Sequence-dependent enhancement of HCT-8 cell kill by trimetrexate and fluoropyrimidines: implications for the mechanism of this interaction.
Sobrero A; Romanini A; Russello O; Nicolin A; Rosso R; Bertino JR
Eur J Cancer Clin Oncol; 1989 Jun; 25(6):977-82. PubMed ID: 2526736
[TBL] [Abstract][Full Text] [Related]
2. Implications for improved high-dose methotrexate therapeutic effects in cultured human breast cancer and bone marrow cells.
Bowen D; Southerland WM; Johnson DH; Hawkins M; Hughes DE
Cancer Detect Prev; 2000; 24(5):452-8. PubMed ID: 11129987
[TBL] [Abstract][Full Text] [Related]
3. Effects of 5-methyltetrahydrofolate on the activity of fluoropyrimidines against human leukemia (CCRF-CEM) cells.
Mini E; Mazzei T; Coronnello M; Criscuoli L; Gualtieri M; Periti P; Bertino JR
Biochem Pharmacol; 1987 Sep; 36(18):2905-11. PubMed ID: 2958010
[TBL] [Abstract][Full Text] [Related]
4. Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil, in CCRF-CEM cells.
Romanini A; Li WW; Colofiore JR; Bertino JR
J Natl Cancer Inst; 1992 Jul; 84(13):1033-8. PubMed ID: 1376779
[TBL] [Abstract][Full Text] [Related]
5. Sequence and schedule-dependent synergy of trimetrexate in combination with 5-fluorouracil in vitro and in mice.
Elliott WL; Howard CT; Dykes DJ; Leopold WR
Cancer Res; 1989 Oct; 49(20):5586-90. PubMed ID: 2477146
[TBL] [Abstract][Full Text] [Related]
6. Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.
Zhang ZG; Malmberg M; Yin MB; Slocum HK; Rustum YM
Biochem Pharmacol; 1993 Mar; 45(5):1157-64. PubMed ID: 8461045
[TBL] [Abstract][Full Text] [Related]
7. Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
Allegra CJ; Hoang K; Yeh GC; Drake JC; Baram J
J Biol Chem; 1987 Oct; 262(28):13520-6. PubMed ID: 2443493
[TBL] [Abstract][Full Text] [Related]
8. Schedule-dependent synergism and antagonism between raltitrexed ("Tomudex") and methotrexate in human colon cancer cell lines in vitro.
Kano Y; Akutsu M; Tsunoda S; Suzuki K; Yazawa Y; Furukawa Y
Jpn J Cancer Res; 2001 Jan; 92(1):74-82. PubMed ID: 11173547
[TBL] [Abstract][Full Text] [Related]
9. Comparative DNA strand breakage induced by FUra and FdUrd in human ileocecal adenocarcinoma (HCT-8) cells: relevance to cell growth inhibition.
Yin MB; Rustum YM
Cancer Commun; 1991 Feb; 3(2):45-51. PubMed ID: 1825284
[TBL] [Abstract][Full Text] [Related]
10. Enhancement of fluoropyrimidine cytotoxicity by 5-methyltetrahydrofolate in a human leukemia cell line, CCRF-CEM.
Mini E; Mazzei T; Coronnello M; Criscuoli L; Gualtieri M; Periti P
Chemioterapia; 1985 Dec; 4(6):454-9. PubMed ID: 2937563
[TBL] [Abstract][Full Text] [Related]
11. Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG2034): comparison across sensitive and resistant human tumor cell lines.
Faessel HM; Slocum HK; Rustum YM; Greco WR
Biochem Pharmacol; 1999 Mar; 57(5):567-77. PubMed ID: 9952321
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic efficacy of fluoropyrimidines depends on the duration of thymidylate synthase inhibition in the murine colon 26-B carcinoma tumor model.
van Laar JA; van der Wilt CL; Rustum YM; Noordhuis P; Smid K; Pinedo HM; Peters GJ
Clin Cancer Res; 1996 Aug; 2(8):1327-33. PubMed ID: 9816304
[TBL] [Abstract][Full Text] [Related]
13. Pretreatment of colon carcinoma cells with Tomudex enhances 5-fluorouracil cytotoxicity.
Longo GS; Izzo J; Chang YM; Tong WP; Zielinski Z; Gorlick R; Chou TC; Bertino JR
Clin Cancer Res; 1998 Feb; 4(2):469-73. PubMed ID: 9516938
[TBL] [Abstract][Full Text] [Related]
14. Rapid development of resistance to antifolates in vitro: possible clinical implication.
Sobrero A; Aschele C; Rosso R; Nicolin A; Bertino JR
J Natl Cancer Inst; 1991 Jan; 83(1):24-8. PubMed ID: 1824599
[TBL] [Abstract][Full Text] [Related]
15. Sequence dependent synergistic cytotoxicity between etoposide and fluoropyrimidines.
Damon LE; Christensen S; Rochlitz C; Cadman EC
Anticancer Res; 1989; 9(6):1761-7. PubMed ID: 2534035
[TBL] [Abstract][Full Text] [Related]
16. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
Miyachi H; Takemura Y; Kobayashi H; Ando Y
Jpn J Cancer Res; 1997 Sep; 88(9):900-6. PubMed ID: 9369939
[TBL] [Abstract][Full Text] [Related]
17. Antifolate drug interactions: enhancement of growth inhibition due to the antipurine 5,10-dideazatetrahydrofolic acid by the lipophilic dihydrofolate reductase inhibitors metoprine and trimetrexate.
Galivan J; Nimec Z; Rhee M; Boschelli D; Oronsky AL; Kerwar SS
Cancer Res; 1988 May; 48(9):2421-5. PubMed ID: 2965613
[TBL] [Abstract][Full Text] [Related]
18. Biomodulation of 5-fluorouracil with antifolates.
Bertino JR
Semin Oncol; 1997 Oct; 24(5 Suppl 18):S18-52-S18-56. PubMed ID: 9420021
[TBL] [Abstract][Full Text] [Related]
19. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
Pizzorno G; Chang YM; McGuire JJ; Bertino JR
Cancer Res; 1989 Oct; 49(19):5275-80. PubMed ID: 2475246
[TBL] [Abstract][Full Text] [Related]
20. Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
Galivan J; Nimec Z; Rhee M
Cancer Res; 1987 Oct; 47(20):5256-60. PubMed ID: 2958130
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]