BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 25267403)

  • 1. Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.
    Dong Y; Van Tine BA; Oyama T; Wang PI; Cheng EH; Hsieh JJ
    Cell Res; 2014 Nov; 24(11):1354-66. PubMed ID: 25267403
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.
    Takeda S; Chen DY; Westergard TD; Fisher JK; Rubens JA; Sasagawa S; Kan JT; Korsmeyer SJ; Cheng EH; Hsieh JJ
    Genes Dev; 2006 Sep; 20(17):2397-409. PubMed ID: 16951254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.
    Cabodi S; Tinnirello A; Di Stefano P; Bisarò B; Ambrosino E; Castellano I; Sapino A; Arisio R; Cavallo F; Forni G; Glukhova M; Silengo L; Altruda F; Turco E; Tarone G; Defilippi P
    Cancer Res; 2006 May; 66(9):4672-80. PubMed ID: 16651418
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia.
    Zhao Z; Wang L; Volk AG; Birch NW; Stoltz KL; Bartom ET; Marshall SA; Rendleman EJ; Nestler CM; Shilati J; Schiltz GE; Crispino JD; Shilatifard A
    Genes Dev; 2019 Jan; 33(1-2):61-74. PubMed ID: 30573454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.
    Wellberg EA; Johnson S; Finlay-Schultz J; Lewis AS; Terrell KL; Sartorius CA; Abel ED; Muller WJ; Anderson SM
    Breast Cancer Res; 2016 Dec; 18(1):131. PubMed ID: 27998284
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells.
    Muraoka RS; Lenferink AE; Law B; Hamilton E; Brantley DM; Roebuck LR; Arteaga CL
    Mol Cell Biol; 2002 Apr; 22(7):2204-19. PubMed ID: 11884607
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.
    Niizuma H; Searleman AC; Takeda S; Armstrong SA; Park CY; Cheng EH; Hsieh JJ
    JCI Insight; 2021 Aug; 6(15):. PubMed ID: 34156981
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors.
    Landis MD; Seachrist DD; Abdul-Karim FW; Keri RA
    Oncogene; 2006 Jun; 25(23):3325-34. PubMed ID: 16434967
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium.
    Tarulli GA; De Silva D; Ho V; Kunasegaran K; Ghosh K; Tan BC; Bulavin DV; Pietersen AM
    Breast Cancer Res; 2013 Jan; 15(1):R10. PubMed ID: 23369183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.
    Sriram R; Lo V; Pryce B; Antonova L; Mears AJ; Daneshmand M; McKay B; Conway SJ; Muller WJ; Sabourin LA
    Breast Cancer Res; 2015 Jan; 17(1):7. PubMed ID: 25592291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression.
    Hsieh JJ; Cheng EH; Korsmeyer SJ
    Cell; 2003 Oct; 115(3):293-303. PubMed ID: 14636557
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein.
    Sabiani S; Geppert T; Engelbrecht C; Kowarz E; Schneider G; Marschalek R
    EBioMedicine; 2015 May; 2(5):386-95. PubMed ID: 26137584
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ADAMTS18 deficiency associates extracellular matrix dysfunction with a higher risk of HER2-positive mammary tumorigenesis and metastasis.
    Nie J; Dang S; Zhu R; Lu T; Zhang W
    Breast Cancer Res; 2024 Jan; 26(1):19. PubMed ID: 38287441
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
    Lenferink AE; Simpson JF; Shawver LK; Coffey RJ; Forbes JT; Arteaga CL
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9609-14. PubMed ID: 10931950
    [TBL] [Abstract][Full Text] [Related]  

  • 15. USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity.
    Kuang X; Salinger A; Benavides F; Muller WJ; Dent SYR; Koutelou E
    PLoS One; 2024; 19(1):e0290837. PubMed ID: 38236941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.
    Brantley-Sieders DM; Zhuang G; Hicks D; Fang WB; Hwang Y; Cates JM; Coffman K; Jackson D; Bruckheimer E; Muraoka-Cook RS; Chen J
    J Clin Invest; 2008 Jan; 118(1):64-78. PubMed ID: 18079969
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of miR-489 derails mammary hierarchy structure and inhibits HER2/neu-induced tumorigenesis.
    Patel Y; Soni M; Awgulewitsch A; Kern MJ; Liu S; Shah N; Singh UP; Chen H
    Oncogene; 2019 Jan; 38(3):445-453. PubMed ID: 30104710
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo.
    Ramovs V; Secades P; Song JY; Thijssen B; Kreft M; Sonnenberg A
    Breast Cancer Res; 2019 May; 21(1):63. PubMed ID: 31101121
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling.
    Lo PK; Kanojia D; Liu X; Singh UP; Berger FG; Wang Q; Chen H
    Oncogene; 2012 May; 31(21):2614-26. PubMed ID: 21996747
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hunk is required for HER2/neu-induced mammary tumorigenesis.
    Yeh ES; Yang TW; Jung JJ; Gardner HP; Cardiff RD; Chodosh LA
    J Clin Invest; 2011 Mar; 121(3):866-79. PubMed ID: 21393859
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.