These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function. Kumari K; Tlapak-Simmons VL; Baggenstoss BA; Weigel PH J Biol Chem; 2002 Apr; 277(16):13943-51. PubMed ID: 11799120 [TBL] [Abstract][Full Text] [Related]
3. Identification of a membrane-localized cysteine cluster near the substrate-binding sites of the Streptococcus equisimilis hyaluronan synthase. Kumari K; Weigel PH Glycobiology; 2005 May; 15(5):529-39. PubMed ID: 15616126 [TBL] [Abstract][Full Text] [Related]
4. Hyaluronan synthase polymerizing activity and control of product size are discrete enzyme functions that can be uncoupled by mutagenesis of conserved cysteines. Weigel PH; Baggenstoss BA Glycobiology; 2012 Oct; 22(10):1302-10. PubMed ID: 22745284 [TBL] [Abstract][Full Text] [Related]
5. Kinetic characterization of the recombinant hyaluronan synthases from Streptococcus pyogenes and Streptococcus equisimilis. Tlapak-Simmons VL; Baggenstoss BA; Kumari K; Heldermon C; Weigel PH J Biol Chem; 1999 Feb; 274(7):4246-53. PubMed ID: 9933624 [TBL] [Abstract][Full Text] [Related]
6. Characterization of the purified hyaluronan synthase from Streptococcus equisimilis. Tlapak-Simmons VL; Baron CA; Weigel PH Biochemistry; 2004 Jul; 43(28):9234-42. PubMed ID: 15248781 [TBL] [Abstract][Full Text] [Related]
7. Hyaluronan synthase assembles hyaluronan on a [GlcNAc(β1,4)]n-GlcNAc(α1→)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end. Weigel PH; Baggenstoss BA; Washburn JL Glycobiology; 2017 Jun; 27(6):536-554. PubMed ID: 28138013 [TBL] [Abstract][Full Text] [Related]
8. Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif. Baggenstoss BA; Harris EN; Washburn JL; Medina AP; Nguyen L; Weigel PH Glycobiology; 2017 Jan; 27(2):154-164. PubMed ID: 27558839 [TBL] [Abstract][Full Text] [Related]
9. Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis. Kumari K; Weigel PH J Biol Chem; 1997 Dec; 272(51):32539-46. PubMed ID: 9405467 [TBL] [Abstract][Full Text] [Related]
10. Purification and lipid dependence of the recombinant hyaluronan synthases from Streptococcus pyogenes and Streptococcus equisimilis. Tlapak-Simmons VL; Baggenstoss BA; Clyne T; Weigel PH J Biol Chem; 1999 Feb; 274(7):4239-45. PubMed ID: 9933623 [TBL] [Abstract][Full Text] [Related]
11. Site-directed mutation of conserved cysteine residues does not inactivate the Streptococcus pyogenes hyaluronan synthase. Heldermon CD; Tlapak-Simmons VL; Baggenstoss BA; Weigel PH Glycobiology; 2001 Dec; 11(12):1017-24. PubMed ID: 11805074 [TBL] [Abstract][Full Text] [Related]
15. Mutation of two intramembrane polar residues conserved within the hyaluronan synthase family alters hyaluronan product size. Kumari K; Baggenstoss BA; Parker AL; Weigel PH J Biol Chem; 2006 Apr; 281(17):11755-60. PubMed ID: 16505475 [TBL] [Abstract][Full Text] [Related]
16. Key Role of the Carboxyl Terminus of Hyaluronan Synthase in Processive Synthesis and Size Control of Hyaluronic Acid Polymers. Yang J; Cheng F; Yu H; Wang J; Guo Z; Stephanopoulos G Biomacromolecules; 2017 Apr; 18(4):1064-1073. PubMed ID: 28192668 [TBL] [Abstract][Full Text] [Related]
17. Metal dependency for transcription factor rho activation. Weber TP; Widger WR; Kohn H Biochemistry; 2003 Feb; 42(6):1652-9. PubMed ID: 12578379 [TBL] [Abstract][Full Text] [Related]
18. Induction of catalytic activity of plasminogen by monoclonal antibody IV-Ic in the presence of divalent metal cations and alpha2-antiplasmin. Sokolovskaya LI; Slominskii AY; Volkov GL Biochemistry (Mosc); 2006 Jun; 71(6):627-33. PubMed ID: 16827654 [TBL] [Abstract][Full Text] [Related]