These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 25268741)

  • 1. Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism.
    Waraky A; Akopyan K; Parrow V; Strömberg T; Axelson M; Abrahmsén L; Lindqvist A; Larsson O; Aleem E
    Oncotarget; 2014 Sep; 5(18):8379-92. PubMed ID: 25268741
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells.
    Tsai AC; Pai HC; Wang CY; Liou JP; Teng CM; Wang JC; Pan SL
    Br J Pharmacol; 2014 Jan; 171(1):122-33. PubMed ID: 24116948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models.
    Chen JY; Tang YA; Li WS; Chiou YC; Shieh JM; Wang YC
    PLoS One; 2013; 8(4):e62082. PubMed ID: 23646116
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Chang WL; Yu CC; Chen CS; Guh JH
    Biochem Pharmacol; 2015 Mar; 94(1):12-21. PubMed ID: 25615907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
    Strömberg T; Feng X; Delforoush M; Berglund M; Lin Y; Axelson M; Larsson O; Georgii-Hemming P; Lennartsson J; Enblad G
    Med Oncol; 2015 Jul; 32(7):188. PubMed ID: 26021470
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
    Vasilcanu R; Vasilcanu D; Sehat B; Yin S; Girnita A; Axelson M; Girnita L
    Mol Pharmacol; 2008 Mar; 73(3):930-9. PubMed ID: 18070930
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.
    Strömberg T; Ekman S; Girnita L; Dimberg LY; Larsson O; Axelson M; Lennartsson J; Hellman U; Carlson K; Osterborg A; Vanderkerken K; Nilsson K; Jernberg-Wiklund H
    Blood; 2006 Jan; 107(2):669-78. PubMed ID: 16166596
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells.
    Lee ST; Lee JY; Han CR; Kim YH; Jun do Y; Taub D; Kim YH
    Biochem Pharmacol; 2015 Apr; 94(4):257-69. PubMed ID: 25732194
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1.
    Silva VC; Cassimeris L
    Mol Biol Cell; 2013 Dec; 24(24):3819-31. PubMed ID: 24152729
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS; Choi HE; Shin JS; Cho YW; Choi JH; Cho WJ; Lee KT
    Carcinogenesis; 2013 Aug; 34(8):1852-60. PubMed ID: 23615402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.
    Wang Q; Wei F; Lv G; Li C; Liu T; Hadjipanayis CG; Zhang G; Hao C; Bellail AC
    BMC Cancer; 2013 Nov; 13():521. PubMed ID: 24182354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Newly synthesized podophyllotoxin derivative, LJ12, induces apoptosis and mitotic catastrophe in non-small cell lung cancer cells in vitro.
    Hui L; Sang C; Wang D; Wang X; Wang M; Jia Q; Ma M; Chen S
    Mol Med Rep; 2016 Jan; 13(1):339-46. PubMed ID: 26573436
    [TBL] [Abstract][Full Text] [Related]  

  • 13. T0070907, a PPAR γ inhibitor, induced G2/M arrest enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe.
    An Z; Muthusami S; Yu JR; Park WY
    Reprod Sci; 2014 Nov; 21(11):1352-61. PubMed ID: 24642720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Picropodophyllin inhibits tumor growth of human nasopharyngeal carcinoma in a mouse model.
    Yin SC; Guo W; Tao ZZ
    Biochem Biophys Res Commun; 2013 Sep; 439(1):1-5. PubMed ID: 23973483
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol.
    Choi HJ; Zhu BT
    Biochim Biophys Acta; 2012 Aug; 1823(8):1306-15. PubMed ID: 22580043
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.
    Zhang Q; Pan J; Lubet RA; Wang Y; You M
    Mol Carcinog; 2015 Jun; 54 Suppl 1():E129-37. PubMed ID: 25163779
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel quinazoline-based analog induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells via a ROS-dependent mechanism.
    Shi H; Li Y; Ren X; Zhang Y; Yang Z; Qi C
    Biochem Biophys Res Commun; 2017 Apr; 486(2):314-320. PubMed ID: 28302490
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
    Ling YH; Jiang JD; Holland JF; Perez-Soler R
    Mol Pharmacol; 2002 Sep; 62(3):529-38. PubMed ID: 12181429
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe.
    Bai Z; Gao M; Zhang H; Guan Q; Xu J; Li Y; Qi H; Li Z; Zuo D; Zhang W; Wu Y
    Cancer Lett; 2017 Aug; 402():81-92. PubMed ID: 28576750
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.
    Liao YJ; Bai HY; Li ZH; Zou J; Chen JW; Zheng F; Zhang JX; Mai SJ; Zeng MS; Sun HD; Pu JX; Xie D
    Cell Death Dis; 2014 Mar; 5(3):e1137. PubMed ID: 24651440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.