BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 25270903)

  • 1. A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome.
    Liu Y; Duan W; Guo Y; Li Z; Han H; Zhang S; Yuan P; Li C
    Neuroscience; 2014 Dec; 281():88-98. PubMed ID: 25270903
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells.
    Cicardi ME; Cristofani R; Rusmini P; Meroni M; Ferrari V; Vezzoli G; Tedesco B; Piccolella M; Messi E; Galbiati M; Boncoraglio A; Carra S; Crippa V; Poletti A
    Sci Rep; 2018 Aug; 8(1):12390. PubMed ID: 30120266
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS).
    Hanson KA; Kim SH; Wassarman DA; Tibbetts RS
    J Biol Chem; 2010 Apr; 285(15):11068-72. PubMed ID: 20154090
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
    Hergesheimer RC; Chami AA; de Assis DR; Vourc'h P; Andres CR; Corcia P; Lanznaster D; Blasco H
    Brain; 2019 May; 142(5):1176-1194. PubMed ID: 30938443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Raloxifene, a promising estrogen replacement, limits TDP-25 cell death by enhancing autophagy and suppressing apoptosis.
    Zhou F; Dong H; Liu Y; Yan L; Sun C; Hao P; Liu Y; Zhai J; Liu Y
    Brain Res Bull; 2018 Jun; 140():281-290. PubMed ID: 29807145
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1.
    Kim SH; Shi Y; Hanson KA; Williams LM; Sakasai R; Bowler MJ; Tibbetts RS
    J Biol Chem; 2009 Mar; 284(12):8083-92. PubMed ID: 19112176
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43.
    Caccamo A; Shaw DM; Guarino F; Messina A; Walker AW; Oddo S
    Hum Mol Genet; 2015 Aug; 24(16):4625-35. PubMed ID: 26002100
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy.
    Cascella R; Fani G; Capitini C; Rusmini P; Poletti A; Cecchi C; Chiti F
    FASEB J; 2017 Dec; 31(12):5609-5624. PubMed ID: 28842427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity.
    Li Q; Yokoshi M; Okada H; Kawahara Y
    Nat Commun; 2015 Jan; 6():6183. PubMed ID: 25630387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
    Wächter N; Storch A; Hermann A
    Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.
    Nonaka T; Arai T; Buratti E; Baralle FE; Akiyama H; Hasegawa M
    FEBS Lett; 2009 Jan; 583(2):394-400. PubMed ID: 19111550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PABPN1 suppresses TDP-43 toxicity in ALS disease models.
    Chou CC; Alexeeva OM; Yamada S; Pribadi A; Zhang Y; Mo B; Williams KR; Zarnescu DC; Rossoll W
    Hum Mol Genet; 2015 Sep; 24(18):5154-73. PubMed ID: 26130692
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Intracellular seeded aggregation of TDP-43].
    Nonaka T; Hasegawa M
    Rinsho Shinkeigaku; 2012; 52(11):1056-8. PubMed ID: 23196514
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TDP-43 modification in the hSOD1(G93A) amyotrophic lateral sclerosis mouse model.
    Cai M; Lee KW; Choi SM; Yang EJ
    Neurol Res; 2015 Mar; 37(3):253-62. PubMed ID: 25213598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.
    Tanaka Y; Nonaka T; Suzuki G; Kametani F; Hasegawa M
    Hum Mol Genet; 2016 Apr; 25(7):1420-33. PubMed ID: 26908597
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [The molecular mechanisms of intracellular TDP-43 aggregates].
    Nonaka T; Arai T; Hasegawa M
    Brain Nerve; 2009 Nov; 61(11):1292-300. PubMed ID: 19938686
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.
    Cragnaz L; Spinelli G; De Conti L; Bureau EA; Brownlees J; Feiguin F; Romano V; Skoko N; Klima R; Kettleborough CA; Baralle FE; Baralle M
    Neurobiol Dis; 2021 Dec; 160():105515. PubMed ID: 34571136
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Molecular mechanism of amyotrophic lateral sclerosis (ALS) from the viewpoint of the formation and degeneration of transactive response DNA-binding protein 43 kDa (TDP-43) inclusions].
    Kasahara S; Ishihara T; Koike Y; Sugai A; Onodera O
    Rinsho Shinkeigaku; 2020 Feb; 60(2):109-116. PubMed ID: 31956195
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).
    Volkening K; Leystra-Lantz C; Yang W; Jaffee H; Strong MJ
    Brain Res; 2009 Dec; 1305():168-82. PubMed ID: 19815002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.