BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 25271156)

  • 1. Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling.
    Chen X; Bai B; Tian Y; Du H; Chen J
    J Biol Chem; 2014 Nov; 289(45):31173-87. PubMed ID: 25271156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Individual phosphorylation sites at the C-terminus of the apelin receptor play different roles in signal transduction.
    Chen J; Chen X; Li S; Jiang Y; Mao H; Zhang R; Ji B; Yan M; Cai X; Wang C
    Redox Biol; 2020 Sep; 36():101629. PubMed ID: 32863206
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GPCR structure and function relationship: identification of a biased apelin receptor mutant.
    Ban T; Li X; Ma X; Yang H; Song Y; Sun Y; Shen M; Li N; Zhang MY; Ma Y; Zhong W; Zhang M; Hu LA
    Biochem J; 2018 Dec; 475(23):3813-3826. PubMed ID: 30409826
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling.
    Chen J; Wang Z; Zhang R; Yin H; Wang P; Wang C; Jiang Y
    Life Sci; 2023 Sep; 328():121892. PubMed ID: 37364634
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Apelin binding to human APJ receptor leads to biased signaling.
    Kumar P; Ashokan A; Aradhyam GK
    Biochim Biophys Acta; 2016 Dec; 1864(12):1748-1756. PubMed ID: 27671350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Agonist-induced internalization and desensitization of the apelin receptor.
    Pope GR; Tilve S; McArdle CA; Lolait SJ; O'Carroll AM
    Mol Cell Endocrinol; 2016 Dec; 437():108-119. PubMed ID: 27492965
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure.
    Gargalovic P; Wong P; Onorato J; Finlay H; Wang T; Yan M; Crain E; St-Onge S; Héroux M; Bouvier M; Xu C; Chen XQ; Generaux C; Lawrence M; Wexler R; Gordon D
    Circ Heart Fail; 2021 Mar; 14(3):e007351. PubMed ID: 33663236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.
    Coquerel D; Delile E; Dumont L; Chagnon F; Murza A; Sainsily X; Salvail D; Sarret P; Marsault E; Auger-Messier M; Lesur O
    Am J Physiol Heart Circ Physiol; 2021 Apr; 320(4):H1646-H1656. PubMed ID: 33635165
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity.
    Zhou N; Zhang X; Fan X; Argyris E; Fang J; Acheampong E; DuBois GC; Pomerantz RJ
    Virology; 2003 Dec; 317(1):84-94. PubMed ID: 14675627
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterodimerization of human apelin and bradykinin 1 receptors: novel signal transduction characteristics.
    Bai B; Liu L; Zhang N; Wang C; Jiang Y; Chen J
    Cell Signal; 2014 Jul; 26(7):1549-59. PubMed ID: 24686079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK(1/2) and cell proliferation via Gαq-mediated mechanism.
    Bai B; Cai X; Jiang Y; Karteris E; Chen J
    J Cell Mol Med; 2014 Oct; 18(10):2071-81. PubMed ID: 25164432
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine.
    Ceraudo E; Galanth C; Carpentier E; Banegas-Font I; Schonegge AM; Alvear-Perez R; Iturrioz X; Bouvier M; Llorens-Cortes C
    J Biol Chem; 2014 Aug; 289(35):24599-610. PubMed ID: 25012663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice.
    Li N; Ma X; Ban T; Xu S; Ma Y; Ason B; Hu LA
    Biochem J; 2020 Sep; 477(17):3313-3327. PubMed ID: 32779693
    [TBL] [Abstract][Full Text] [Related]  

  • 14. By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization.
    Iturrioz X; Gerbier R; Leroux V; Alvear-Perez R; Maigret B; Llorens-Cortes C
    J Biol Chem; 2010 Oct; 285(42):32627-37. PubMed ID: 20675385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.
    Kang Y; Kim J; Anderson JP; Wu J; Gleim SR; Kundu RK; McLean DL; Kim JD; Park H; Jin SW; Hwa J; Quertermous T; Chun HJ
    Circ Res; 2013 Jun; 113(1):22-31. PubMed ID: 23603510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. APJ acts as a dual receptor in cardiac hypertrophy.
    Scimia MC; Hurtado C; Ray S; Metzler S; Wei K; Wang J; Woods CE; Purcell NH; Catalucci D; Akasaka T; Bueno OF; Vlasuk GP; Kaliman P; Bodmer R; Smith LH; Ashley E; Mercola M; Brown JH; Ruiz-Lozano P
    Nature; 2012 Aug; 488(7411):394-8. PubMed ID: 22810587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment.
    Besserer-Offroy É; Bérubé P; Côté J; Murza A; Longpré JM; Dumaine R; Lesur O; Auger-Messier M; Leduc R; Marsault É; Sarret P
    Pharmacol Res; 2018 May; 131():7-16. PubMed ID: 29530600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition.
    Parikh VN; Liu J; Shang C; Woods C; Chang AC; Zhao M; Charo DN; Grunwald Z; Huang Y; Seo K; Tsao PS; Bernstein D; Ruiz-Lozano P; Quertermous T; Ashley EA
    Am J Physiol Heart Circ Physiol; 2018 Aug; 315(2):H348-H356. PubMed ID: 29775410
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Effects of Apelin and Elabela Ligands on Apelin Receptor Distinct Signaling Profiles.
    Jiang Y; Yan M; Wang C; Wang Q; Chen X; Zhang R; Wan L; Ji B; Dong B; Wang H; Chen J
    Front Pharmacol; 2021; 12():630548. PubMed ID: 33746758
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Receptor Signaling.
    Galon-Tilleman H; Yang H; Bednarek MA; Spurlock SM; Paavola KJ; Ko B; To C; Luo J; Tian H; Jermutus L; Grimsby J; Rondinone CM; Konkar A; Kaplan DD
    J Biol Chem; 2017 Feb; 292(5):1925-1933. PubMed ID: 27994053
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.