184 related articles for article (PubMed ID: 25271362)
1. The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling.
Tsoi H; Li L; Chen ZS; Lau KF; Tsui SK; Chan HY
Biochem J; 2014 Dec; 464(3):439-47. PubMed ID: 25271362
[TBL] [Abstract][Full Text] [Related]
2. The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway.
Chan CM; Ma CW; Chan WY; Chan HY
Arch Biochem Biophys; 2007 Mar; 459(2):197-207. PubMed ID: 17306213
[TBL] [Abstract][Full Text] [Related]
3. Full Activation of Kinase Protein Kinase B by Phosphoinositide-Dependent Protein Kinase-1 and Mammalian Target of Rapamycin Complex 2 Is Required for Early Natural Killer Cell Development and Survival.
He J; Zhao J; Quan Y; Hou X; Yang M; Dong Z
Front Immunol; 2020; 11():617404. PubMed ID: 33633735
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
Wick MJ; Dong LQ; Riojas RA; Ramos FJ; Liu F
J Biol Chem; 2000 Dec; 275(51):40400-6. PubMed ID: 11006271
[TBL] [Abstract][Full Text] [Related]
5. Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo.
Calleja V; Alcor D; Laguerre M; Park J; Vojnovic B; Hemmings BA; Downward J; Parker PJ; Larijani B
PLoS Biol; 2007 Apr; 5(4):e95. PubMed ID: 17407381
[TBL] [Abstract][Full Text] [Related]
6. Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival.
Zurashvili T; Cordón-Barris L; Ruiz-Babot G; Zhou X; Lizcano JM; Gómez N; Giménez-Llort L; Bayascas JR
Mol Cell Biol; 2013 Mar; 33(5):1027-40. PubMed ID: 23275438
[TBL] [Abstract][Full Text] [Related]
7. Serine 396 of PDK1 is required for maximal PKB activation.
Moon Z; Wang Y; Aryan N; Mousseau DD; Scheid MP
Cell Signal; 2008 Nov; 20(11):2038-49. PubMed ID: 18718528
[TBL] [Abstract][Full Text] [Related]
8. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Bayascas JR; Wullschleger S; Sakamoto K; García-Martínez JM; Clacher C; Komander D; van Aalten DM; Boini KM; Lang F; Lipina C; Logie L; Sutherland C; Chudek JA; van Diepen JA; Voshol PJ; Lucocq JM; Alessi DR
Mol Cell Biol; 2008 May; 28(10):3258-72. PubMed ID: 18347057
[TBL] [Abstract][Full Text] [Related]
9. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
Alessi DR; Deak M; Casamayor A; Caudwell FB; Morrice N; Norman DG; Gaffney P; Reese CB; MacDougall CN; Harbison D; Ashworth A; Bownes M
Curr Biol; 1997 Oct; 7(10):776-89. PubMed ID: 9368760
[TBL] [Abstract][Full Text] [Related]
10. PDK1 and PKB/Akt: ideal targets for development of new strategies to structure-based drug design.
Harris TK
IUBMB Life; 2003 Mar; 55(3):117-26. PubMed ID: 12822887
[TBL] [Abstract][Full Text] [Related]
11. Physical association of PDK1 with AKT1 is sufficient for pathway activation independent of membrane localization and phosphatidylinositol 3 kinase.
Ding Z; Liang J; Li J; Lu Y; Ariyaratna V; Lu Z; Davies MA; Westwick JK; Mills GB
PLoS One; 2010 Mar; 5(3):e9910. PubMed ID: 20361045
[TBL] [Abstract][Full Text] [Related]
12. Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction.
Watton SJ; Downward J
Curr Biol; 1999 Apr; 9(8):433-6. PubMed ID: 10226029
[TBL] [Abstract][Full Text] [Related]
13. Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation.
Waugh C; Sinclair L; Finlay D; Bayascas JR; Cantrell D
Mol Cell Biol; 2009 Nov; 29(21):5952-62. PubMed ID: 19703999
[TBL] [Abstract][Full Text] [Related]
14. 3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner.
Gagliardi PA; di Blasio L; Orso F; Seano G; Sessa R; Taverna D; Bussolino F; Primo L
Neoplasia; 2012 Aug; 14(8):719-31. PubMed ID: 22952425
[TBL] [Abstract][Full Text] [Related]
15. The SARS coronavirus nucleocapsid protein induces actin reorganization and apoptosis in COS-1 cells in the absence of growth factors.
Surjit M; Liu B; Jameel S; Chow VT; Lal SK
Biochem J; 2004 Oct; 383(Pt 1):13-8. PubMed ID: 15294014
[TBL] [Abstract][Full Text] [Related]
16. The PI3K-PDK1 connection: more than just a road to PKB.
Vanhaesebroeck B; Alessi DR
Biochem J; 2000 Mar; 346 Pt 3(Pt 3):561-76. PubMed ID: 10698680
[TBL] [Abstract][Full Text] [Related]
17. Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.
Fujita N; Sato S; Ishida A; Tsuruo T
J Biol Chem; 2002 Mar; 277(12):10346-53. PubMed ID: 11779851
[TBL] [Abstract][Full Text] [Related]
18. CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt.
Fukuda T; Guo L; Shi X; Wu C
J Cell Biol; 2003 Mar; 160(7):1001-8. PubMed ID: 12654898
[TBL] [Abstract][Full Text] [Related]
19. Mechanisms and consequences of activation of protein kinase B/Akt.
Downward J
Curr Opin Cell Biol; 1998 Apr; 10(2):262-7. PubMed ID: 9561851
[TBL] [Abstract][Full Text] [Related]
20. Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).
Wrede CE; Dickson LM; Lingohr MK; Briaud I; Rhodes CJ
J Biol Chem; 2002 Dec; 277(51):49676-84. PubMed ID: 12393870
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]