BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 25271621)

  • 1. Cholestenoic acids regulate motor neuron survival via liver X receptors.
    Theofilopoulos S; Griffiths WJ; Crick PJ; Yang S; Meljon A; Ogundare M; Kitambi SS; Lockhart A; Tuschl K; Clayton PT; Morris AA; Martinez A; Reddy MA; Martinuzzi A; Bassi MT; Honda A; Mizuochi T; Kimura A; Nittono H; De Michele G; Carbone R; Criscuolo C; Yau JL; Seckl JR; Schüle R; Schöls L; Sailer AW; Kuhle J; Fraidakis MJ; Gustafsson JÅ; Steffensen KR; Björkhem I; Ernfors P; Sjövall J; Arenas E; Wang Y
    J Clin Invest; 2014 Nov; 124(11):4829-42. PubMed ID: 25271621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of 7α,24-dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acids in human cerebrospinal fluid and plasma.
    Abdel-Khalik J; Crick PJ; Yutuc E; DeBarber AE; Duell PB; Steiner RD; Laina I; Wang Y; Griffiths WJ
    Biochimie; 2018 Oct; 153():86-98. PubMed ID: 29960034
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma.
    Griffiths WJ; Crick PJ; Meljon A; Theofilopoulos S; Abdel-Khalik J; Yutuc E; Parker JE; Kelly DE; Kelly SL; Arenas E; Wang Y
    Biochim Biophys Acta Mol Cell Biol Lipids; 2019 Feb; 1864(2):191-211. PubMed ID: 30471425
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?
    Ogundare M; Theofilopoulos S; Lockhart A; Hall LJ; Arenas E; Sjövall J; Brenton AG; Wang Y; Griffiths WJ
    J Biol Chem; 2010 Feb; 285(7):4666-79. PubMed ID: 19996111
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Defective cholesterol metabolism in amyotrophic lateral sclerosis.
    Abdel-Khalik J; Yutuc E; Crick PJ; Gustafsson JÅ; Warner M; Roman G; Talbot K; Gray E; Griffiths WJ; Turner MR; Wang Y
    J Lipid Res; 2017 Jan; 58(1):267-278. PubMed ID: 27811233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chenodeoxycholic acid rescues axonal degeneration in induced pluripotent stem cell-derived neurons from spastic paraplegia type 5 and cerebrotendinous xanthomatosis patients.
    Mou Y; Nandi G; Mukte S; Chai E; Chen Z; Nielsen JE; Nielsen TT; Criscuolo C; Blackstone C; Fraidakis MJ; Li XJ
    Orphanet J Rare Dis; 2023 Apr; 18(1):72. PubMed ID: 37024986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mining for Oxysterols in
    Meljon A; Crick PJ; Yutuc E; Yau JL; Seckl JR; Theofilopoulos S; Arenas E; Wang Y; Griffiths WJ
    Biomolecules; 2019 Apr; 9(4):. PubMed ID: 31013940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analytical strategies for characterization of oxysterol lipidomes: liver X receptor ligands in plasma.
    Griffiths WJ; Crick PJ; Wang Y; Ogundare M; Tuschl K; Morris AA; Bigger BW; Clayton PT; Wang Y
    Free Radic Biol Med; 2013 Jun; 59():69-84. PubMed ID: 22846477
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid.
    Crick PJ; Beckers L; Baes M; Van Veldhoven PP; Wang Y; Griffiths WJ
    Steroids; 2015 Jul; 99(Pt B):172-7. PubMed ID: 25759118
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha.
    Song C; Liao S
    Endocrinology; 2000 Nov; 141(11):4180-4. PubMed ID: 11089551
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potential bile acid precursors in plasma--possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man.
    Axelson M; Sjövall J
    J Steroid Biochem; 1990 Aug; 36(6):631-40. PubMed ID: 2214780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity.
    Álvarez LD; Dansey MV; Grinman DY; Navalesi D; Samaja GA; Del Fueyo MC; Bastiaensen N; Houtman R; Estrin DA; Veleiro AS; Pecci A; Burton G
    Biochim Biophys Acta; 2015 Dec; 1851(12):1577-86. PubMed ID: 26434697
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis.
    Honda A; Salen G; Matsuzaki Y; Batta AK; Xu G; Hirayama T; Tint GS; Doy M; Shefer S
    J Lipid Res; 2005 Feb; 46(2):287-96. PubMed ID: 15576845
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Formation of bile acids in man: conversion of cholesterol into 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol in liver homogenates.
    Björkheim I; Danielsson H; Einarsson K; Johansson G
    J Clin Invest; 1968 Jul; 47(7):1573-82. PubMed ID: 4385432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis.
    Höflinger P; Hauser S; Yutuc E; Hengel H; Griffiths L; Radelfahr F; Howell OW; Wang Y; Connor SL; Duell PB; DeBarber AE; Martus P; Lütjohann D; Griffiths WJ; Schöls L
    J Lipid Res; 2021; 62():100078. PubMed ID: 33891937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).
    Wada T; Kang HS; Angers M; Gong H; Bhatia S; Khadem S; Ren S; Ellis E; Strom SC; Jetten AM; Xie W
    Mol Pharmacol; 2008 Mar; 73(3):891-9. PubMed ID: 18055760
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroendocrinology: cholesterol metabolites regulate motor neuron function.
    Holmes D
    Nat Rev Endocrinol; 2014 Dec; 10(12):700. PubMed ID: 25331283
    [No Abstract]   [Full Text] [Related]  

  • 18. Cholestenoic acid analogues as inverse agonists of the liver X receptors.
    Alvarez LD; Dansey MV; Ogara MF; Peña CI; Houtman R; Veleiro AS; Pecci A; Burton G
    J Steroid Biochem Mol Biol; 2020 May; 199():105585. PubMed ID: 31931135
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX.
    Honda A; Salen G; Matsuzaki Y; Batta AK; Xu G; Leitersdorf E; Tint GS; Erickson SK; Tanaka N; Shefer S
    J Lipid Res; 2001 Feb; 42(2):291-300. PubMed ID: 11181760
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insights into estrogen receptor alpha modulation by cholestenoic acids.
    Dansey MV; Palavecino Ruiz MD; Ogara MF; Pecci A; Burton G; Alvarez LD
    J Steroid Biochem Mol Biol; 2022 Mar; 217():106046. PubMed ID: 34920079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.