These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Conformations and binding pockets of HRas and its guanine nucleotide exchange factors complexes in the guanosine triphosphate exchange process. Xiong Y; Zeng J; Xia F; Cui Q; Deng X; Xu X J Comput Chem; 2022 May; 43(13):906-916. PubMed ID: 35324017 [TBL] [Abstract][Full Text] [Related]
7. Electrostatic control of GTP and GDP binding in the oncoprotein p21ras. Muegge I; Schweins T; Langen R; Warshel A Structure; 1996 Apr; 4(4):475-89. PubMed ID: 8740369 [TBL] [Abstract][Full Text] [Related]
8. Raf-1 is involved in the regulation of the interaction between guanine nucleotide exchange factor and Ha-ras. Evidences for a function of Raf-1 and phosphatidylinositol 3-kinase upstream to Ras. Giglione C; Parmeggiani A J Biol Chem; 1998 Dec; 273(52):34737-44. PubMed ID: 9856997 [TBL] [Abstract][Full Text] [Related]
9. Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel. Killoran RC; Smith MJ J Biol Chem; 2019 Jun; 294(25):9937-9948. PubMed ID: 31088913 [TBL] [Abstract][Full Text] [Related]
10. Probing the wild-type HRas activation mechanism using steered molecular dynamics, understanding the energy barrier and role of water in the activation. Sharma N; Sonavane U; Joshi R Eur Biophys J; 2014 Mar; 43(2-3):81-95. PubMed ID: 24442446 [TBL] [Abstract][Full Text] [Related]
11. A computational study of a recreated G protein-GEF reaction intermediate competent for nucleotide exchange: fate of the Mg ion. Hamida-Rebaï MB; Robert CH PLoS One; 2010 Feb; 5(2):e9142. PubMed ID: 20174625 [TBL] [Abstract][Full Text] [Related]
12. Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42. Kintscher C; Groemping Y J Mol Biol; 2009 Mar; 387(2):270-83. PubMed ID: 19356586 [TBL] [Abstract][Full Text] [Related]
13. A High-Throughput Assay for Rho Guanine Nucleotide Exchange Factors Based on the Transcreener GDP Assay. Reichman M; Schabdach A; Kumar M; Zielinski T; Donover PS; Laury-Kleintop LD; Lowery RG J Biomol Screen; 2015 Dec; 20(10):1294-9. PubMed ID: 26195453 [TBL] [Abstract][Full Text] [Related]
14. A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation. Yin G; Kistler S; George SD; Kuhlmann N; Garvey L; Huynh M; Bagni RK; Lammers M; Der CJ; Campbell SL J Biol Chem; 2017 Mar; 292(11):4446-4456. PubMed ID: 28154176 [TBL] [Abstract][Full Text] [Related]
15. GEF-mediated GDP/GTP exchange by monomeric GTPases: a regulatory role for Mg2+? Pan JY; Wessling-Resnick M Bioessays; 1998 Jun; 20(6):516-21. PubMed ID: 9699463 [TBL] [Abstract][Full Text] [Related]
16. Comparison of ras-p21 bound to GDP and GTP: differences in protein and ligand dynamics. Mello LV; van Aalten DM; Findlay JB Protein Eng; 1997 Apr; 10(4):381-7. PubMed ID: 9194162 [TBL] [Abstract][Full Text] [Related]
17. Mechanism of the nucleotide exchange reaction in eukaryotic polypeptide chain initiation. Characterization of the guanine nucleotide exchange factor as a GTP-binding protein. Dholakia JN; Wahba AJ J Biol Chem; 1989 Jan; 264(1):546-50. PubMed ID: 2491852 [TBL] [Abstract][Full Text] [Related]
19. Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction. Rebhun JF; Castro AF; Quilliam LA J Biol Chem; 2000 Nov; 275(45):34901-8. PubMed ID: 10934204 [TBL] [Abstract][Full Text] [Related]
20. The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins. Zhang B; Zhang Y; Wang Z; Zheng Y J Biol Chem; 2000 Aug; 275(33):25299-307. PubMed ID: 10843989 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]