241 related articles for article (PubMed ID: 25277268)
1. The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor.
Broadbent SD; Ramjeesingh M; Bear CE; Argent BE; Linsdell P; Gray MA
Pflugers Arch; 2015 Aug; 467(8):1783-94. PubMed ID: 25277268
[TBL] [Abstract][Full Text] [Related]
2. G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects.
Bompadre SG; Sohma Y; Li M; Hwang TC
J Gen Physiol; 2007 Apr; 129(4):285-98. PubMed ID: 17353351
[TBL] [Abstract][Full Text] [Related]
3. Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain.
Chan KW; Csanády L; Seto-Young D; Nairn AC; Gadsby DC
J Gen Physiol; 2000 Aug; 116(2):163-80. PubMed ID: 10919864
[TBL] [Abstract][Full Text] [Related]
4. Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator.
Schwiebert EM; Morales MM; Devidas S; Egan ME; Guggino WB
Proc Natl Acad Sci U S A; 1998 Mar; 95(5):2674-9. PubMed ID: 9482946
[TBL] [Abstract][Full Text] [Related]
5. Direct sensing of intracellular pH by the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel.
Chen JH; Cai Z; Sheppard DN
J Biol Chem; 2009 Dec; 284(51):35495-506. PubMed ID: 19837660
[TBL] [Abstract][Full Text] [Related]
6. The most common cystic fibrosis-associated mutation destabilizes the dimeric state of the nucleotide-binding domains of CFTR.
Jih KY; Li M; Hwang TC; Bompadre SG
J Physiol; 2011 Jun; 589(Pt 11):2719-31. PubMed ID: 21486785
[TBL] [Abstract][Full Text] [Related]
7. Conserved allosteric hot spots in the transmembrane domains of cystic fibrosis transmembrane conductance regulator (CFTR) channels and multidrug resistance protein (MRP) pumps.
Wei S; Roessler BC; Chauvet S; Guo J; Hartman JL; Kirk KL
J Biol Chem; 2014 Jul; 289(29):19942-57. PubMed ID: 24876383
[TBL] [Abstract][Full Text] [Related]
8. The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity.
Carson MR; Travis SM; Welsh MJ
J Biol Chem; 1995 Jan; 270(4):1711-7. PubMed ID: 7530246
[TBL] [Abstract][Full Text] [Related]
9. Converting nonhydrolyzable nucleotides to strong cystic fibrosis transmembrane conductance regulator (CFTR) agonists by gain of function (GOF) mutations.
Okeyo G; Wang W; Wei S; Kirk KL
J Biol Chem; 2013 Jun; 288(24):17122-33. PubMed ID: 23620589
[TBL] [Abstract][Full Text] [Related]
10. Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.
Ehrhardt A; Chung WJ; Pyle LC; Wang W; Nowotarski K; Mulvihill CM; Ramjeesingh M; Hong J; Velu SE; Lewis HA; Atwell S; Aller S; Bear CE; Lukacs GL; Kirk KL; Sorscher EJ
J Biol Chem; 2016 Jan; 291(4):1854-1865. PubMed ID: 26627831
[TBL] [Abstract][Full Text] [Related]
11. Protein kinase A regulates ATP hydrolysis and dimerization by a CFTR (cystic fibrosis transmembrane conductance regulator) domain.
Howell LD; Borchardt R; Kole J; Kaz AM; Randak C; Cohn JA
Biochem J; 2004 Feb; 378(Pt 1):151-9. PubMed ID: 14602047
[TBL] [Abstract][Full Text] [Related]
12. Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism that requires neither ATP binding nor dimerization of the nucleotide-binding domains.
Wang W; Bernard K; Li G; Kirk KL
J Biol Chem; 2007 Feb; 282(7):4533-4544. PubMed ID: 17178710
[TBL] [Abstract][Full Text] [Related]
13. Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line.
Lansdell KA; Cai Z; Kidd JF; Sheppard DN
J Physiol; 2000 Apr; 524 Pt 2(Pt 2):317-30. PubMed ID: 10766914
[TBL] [Abstract][Full Text] [Related]
14. The H-loop in the second nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator is required for efficient chloride channel closing.
Kloch M; Milewski M; Nurowska E; Dworakowska B; Cutting GR; Dołowy K
Cell Physiol Biochem; 2010; 25(2-3):169-80. PubMed ID: 20110677
[TBL] [Abstract][Full Text] [Related]
15. The two ATP binding sites of cystic fibrosis transmembrane conductance regulator (CFTR) play distinct roles in gating kinetics and energetics.
Zhou Z; Wang X; Liu HY; Zou X; Li M; Hwang TC
J Gen Physiol; 2006 Oct; 128(4):413-22. PubMed ID: 16966475
[TBL] [Abstract][Full Text] [Related]
16. Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia.
Dong Q; Ernst SE; Ostedgaard LS; Shah VS; Ver Heul AR; Welsh MJ; Randak CO
J Biol Chem; 2015 May; 290(22):14140-53. PubMed ID: 25887396
[TBL] [Abstract][Full Text] [Related]
17. Cystic fibrosis transmembrane conductance regulator-associated ATP release is controlled by a chloride sensor.
Jiang Q; Mak D; Devidas S; Schwiebert EM; Bragin A; Zhang Y; Skach WR; Guggino WB; Foskett JK; Engelhardt JF
J Cell Biol; 1998 Nov; 143(3):645-57. PubMed ID: 9813087
[TBL] [Abstract][Full Text] [Related]
18. An electrostatic interaction at the tetrahelix bundle promotes phosphorylation-dependent cystic fibrosis transmembrane conductance regulator (CFTR) channel opening.
Wang W; Roessler BC; Kirk KL
J Biol Chem; 2014 Oct; 289(44):30364-30378. PubMed ID: 25190805
[TBL] [Abstract][Full Text] [Related]
19. Altering intracellular pH reveals the kinetic basis of intraburst gating in the CFTR Cl
Chen JH; Xu W; Sheppard DN
J Physiol; 2017 Feb; 595(4):1059-1076. PubMed ID: 27779763
[TBL] [Abstract][Full Text] [Related]
20. Intracellular cysteines of the cystic fibrosis transmembrane conductance regulator (CFTR) modulate channel gating.
Ketchum CJ; Yue H; Alessi KA; Devidas S; Guggino WB; Maloney PC
Cell Physiol Biochem; 2002; 12(1):1-8. PubMed ID: 11914543
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]