BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 25278022)

  • 1. The E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.
    Schweiger S; Dorn S; Fuchs M; Köhler A; Matthes F; Müller EC; Wanker E; Schneider R; Krauß S
    J Biol Chem; 2014 Nov; 289(46):31805-31817. PubMed ID: 25278022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac.
    Du H; Wu K; Didoronkute A; Levy MV; Todi N; Shchelokova A; Massiah MA
    PLoS One; 2014; 9(9):e107428. PubMed ID: 25207814
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A.
    Du H; Huang Y; Zaghlula M; Walters E; Cox TC; Massiah MA
    J Biol Chem; 2013 Jul; 288(29):21341-21350. PubMed ID: 23740247
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3.
    Krauss S; Foerster J; Schneider R; Schweiger S
    Cancer Res; 2008 Jun; 68(12):4658-65. PubMed ID: 18559511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Point mutations in GLI3 lead to misregulation of its subcellular localization.
    Krauss S; So J; Hambrock M; Köhler A; Kunath M; Scharff C; Wessling M; Grzeschik KH; Schneider R; Schweiger S
    PLoS One; 2009 Oct; 4(10):e7471. PubMed ID: 19829694
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.
    Cai H; Liu A
    Dev Biol; 2017 Dec; 432(1):72-85. PubMed ID: 28412462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein phosphatase 2A (PP2A)-specific ubiquitin ligase MID1 is a sequence-dependent regulator of translation efficiency controlling 3-phosphoinositide-dependent protein kinase-1 (PDPK-1).
    Aranda-Orgillés B; Rutschow D; Zeller R; Karagiannidis AI; Köhler A; Chen C; Wilson T; Krause S; Roepcke S; Lilley D; Schneider R; Schweiger S
    J Biol Chem; 2011 Nov; 286(46):39945-57. PubMed ID: 21930711
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development.
    Pfirrmann T; Jandt E; Ranft S; Lokapally A; Neuhaus H; Perron M; Hollemann T
    Proc Natl Acad Sci U S A; 2016 Sep; 113(36):10103-8. PubMed ID: 27555585
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mediator modulates Gli3-dependent Sonic hedgehog signaling.
    Zhou H; Kim S; Ishii S; Boyer TG
    Mol Cell Biol; 2006 Dec; 26(23):8667-82. PubMed ID: 17000779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.
    Pan Y; Bai CB; Joyner AL; Wang B
    Mol Cell Biol; 2006 May; 26(9):3365-77. PubMed ID: 16611981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The E3 ubiquitin ligase MID1/TRIM18 promotes atypical ubiquitination of the BRCA2-associated factor 35, BRAF35.
    Zanchetta ME; Napolitano LMR; Maddalo D; Meroni G
    Biochim Biophys Acta Mol Cell Res; 2017 Oct; 1864(10):1844-1854. PubMed ID: 28760657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abrogation of Gli3 expression suppresses the growth of colon cancer cells via activation of p53.
    Kang HN; Oh SC; Kim JS; Yoo YA
    Exp Cell Res; 2012 Mar; 318(5):539-49. PubMed ID: 22227409
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling.
    Cai H; Liu A
    Proc Natl Acad Sci U S A; 2016 Dec; 113(51):14751-14756. PubMed ID: 27930311
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A proteomic approach identifies SAFB-like transcription modulator (SLTM) as a bidirectional regulator of GLI family zinc finger transcription factors.
    Zhang Z; Zhan X; Kim B; Wu J
    J Biol Chem; 2019 Apr; 294(14):5549-5561. PubMed ID: 30782847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
    Mazumdar T; DeVecchio J; Agyeman A; Shi T; Houghton JA
    Oncotarget; 2011 Aug; 2(8):638-45. PubMed ID: 21860067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A.
    Aranda-Orgillés B; Aigner J; Kunath M; Lurz R; Schneider R; Schweiger S
    PLoS One; 2008; 3(10):e3507. PubMed ID: 18949047
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.
    Asaoka Y; Kanai F; Ichimura T; Tateishi K; Tanaka Y; Ohta M; Seto M; Tada M; Ijichi H; Ikenoue T; Kawabe T; Isobe T; Yaffe MB; Omata M
    J Biol Chem; 2010 Feb; 285(6):4185-4194. PubMed ID: 19996099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development.
    Zhan X; Shi X; Zhang Z; Chen Y; Wu JI
    Proc Natl Acad Sci U S A; 2011 Aug; 108(31):12758-63. PubMed ID: 21768360
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals.
    Fu L; Wu H; Cheng SY; Gao D; Zhang L; Zhao Y
    Elife; 2016 May; 5():. PubMed ID: 27146893
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.
    Collison AM; Li J; de Siqueira AP; Lv X; Toop HD; Morris JC; Starkey MR; Hansbro PM; Zhang J; Mattes J
    BMC Pulm Med; 2019 Feb; 19(1):31. PubMed ID: 30732588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.