386 related articles for article (PubMed ID: 25281658)
1. Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration.
Zhan L; Xie Q; Tibbetts RS
Hum Mol Genet; 2015 Feb; 24(3):757-72. PubMed ID: 25281658
[TBL] [Abstract][Full Text] [Related]
2. RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
Ihara R; Matsukawa K; Nagata Y; Kunugi H; Tsuji S; Chihara T; Kuranaga E; Miura M; Wakabayashi T; Hashimoto T; Iwatsubo T
Hum Mol Genet; 2013 Nov; 22(22):4474-84. PubMed ID: 23804749
[TBL] [Abstract][Full Text] [Related]
3. Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi.
Chen J; Xie C; Tian L; Hong L; Wu X; Han J
Proc Natl Acad Sci U S A; 2010 Nov; 107(48):20774-9. PubMed ID: 21076039
[TBL] [Abstract][Full Text] [Related]
4. A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects.
Langellotti S; Romano V; Romano G; Klima R; Feiguin F; Cragnaz L; Romano M; Baralle FE
Dis Model Mech; 2016 Jun; 9(6):659-69. PubMed ID: 27101846
[TBL] [Abstract][Full Text] [Related]
5. Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology.
Anderson EN; Morera AA; Kour S; Cherry JD; Ramesh N; Gleixner A; Schwartz JC; Ebmeier C; Old W; Donnelly CJ; Cheng JP; Kline AE; Kofler J; Stein TD; Pandey UB
Elife; 2021 May; 10():. PubMed ID: 34060470
[TBL] [Abstract][Full Text] [Related]
6. Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling.
Klinedinst S; Wang X; Xiong X; Haenfler JM; Collins CA
J Neurosci; 2013 Jul; 33(31):12764-78. PubMed ID: 23904612
[TBL] [Abstract][Full Text] [Related]
7. A Drosophila model for TDP-43 proteinopathy.
Li Y; Ray P; Rao EJ; Shi C; Guo W; Chen X; Woodruff EA; Fushimi K; Wu JY
Proc Natl Acad Sci U S A; 2010 Feb; 107(7):3169-74. PubMed ID: 20133767
[TBL] [Abstract][Full Text] [Related]
8. Domain specificity of MAP3K family members, MLK and Tak1, for JNK signaling in Drosophila.
Stronach B; Lennox AL; Garlena RA
Genetics; 2014 Jun; 197(2):497-513. PubMed ID: 24429281
[TBL] [Abstract][Full Text] [Related]
9. A member of the p38 mitogen-activated protein kinase family is responsible for transcriptional induction of Dopa decarboxylase in the epidermis of Drosophila melanogaster during the innate immune response.
Davis MM; Primrose DA; Hodgetts RB
Mol Cell Biol; 2008 Aug; 28(15):4883-95. PubMed ID: 18519585
[TBL] [Abstract][Full Text] [Related]
10. Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.
Miguel L; Frébourg T; Campion D; Lecourtois M
Neurobiol Dis; 2011 Feb; 41(2):398-406. PubMed ID: 20951205
[TBL] [Abstract][Full Text] [Related]
11. Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.
Liachko NF; Saxton AD; McMillan PJ; Strovas TJ; Keene CD; Bird TD; Kraemer BC
PLoS Genet; 2019 Dec; 15(12):e1008526. PubMed ID: 31834878
[TBL] [Abstract][Full Text] [Related]
12. PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Lee S; Jeon YM; Cha SJ; Kim S; Kwon Y; Jo M; Jang YN; Lee S; Kim J; Kim SR; Lee KJ; Lee SB; Kim K; Kim HJ
Autophagy; 2020 Aug; 16(8):1396-1412. PubMed ID: 31690171
[TBL] [Abstract][Full Text] [Related]
13. TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Wang P; Deng J; Dong J; Liu J; Bigio EH; Mesulam M; Wang T; Sun L; Wang L; Lee AY; McGee WA; Chen X; Fushimi K; Zhu L; Wu JY
PLoS Genet; 2019 May; 15(5):e1007947. PubMed ID: 31100073
[TBL] [Abstract][Full Text] [Related]
14. Depletion of Ubiquilin induces an augmentation in soluble ubiquitinated Drosophila TDP-43 to drive neurotoxicity in the fly.
Jantrapirom S; Lo Piccolo L; Yoshida H; Yamaguchi M
Biochim Biophys Acta Mol Basis Dis; 2018 Sep; 1864(9 Pt B):3038-3049. PubMed ID: 29936333
[TBL] [Abstract][Full Text] [Related]
15. Urm1: an essential regulator of JNK signaling and oxidative stress in Drosophila melanogaster.
Khoshnood B; Dacklin I; Grabbe C
Cell Mol Life Sci; 2016 May; 73(9):1939-54. PubMed ID: 26715182
[TBL] [Abstract][Full Text] [Related]
16. Wallenda regulates JNK-mediated cell death in Drosophila.
Ma X; Xu W; Zhang D; Yang Y; Li W; Xue L
Cell Death Dis; 2015 May; 6(5):e1737. PubMed ID: 25950467
[TBL] [Abstract][Full Text] [Related]
17. Drosophila heat shock response requires the JNK pathway and phosphorylation of mixed lineage kinase at a conserved serine-proline motif.
Gonda RL; Garlena RA; Stronach B
PLoS One; 2012; 7(7):e42369. PubMed ID: 22848763
[TBL] [Abstract][Full Text] [Related]
18. The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia.
Petersen AJ; Katzenberger RJ; Wassarman DA
Genetics; 2013 May; 194(1):133-42. PubMed ID: 23502677
[TBL] [Abstract][Full Text] [Related]
19. TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling.
Zhang T; Mullane PC; Periz G; Wang J
Hum Mol Genet; 2011 May; 20(10):1952-65. PubMed ID: 21355045
[TBL] [Abstract][Full Text] [Related]
20. Disease animal models of TDP-43 proteinopathy and their pre-clinical applications.
Liu YC; Chiang PM; Tsai KJ
Int J Mol Sci; 2013 Oct; 14(10):20079-111. PubMed ID: 24113586
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
