216 related articles for article (PubMed ID: 25281859)
1. Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice.
Hendrikx T; Jeurissen ML; Bieghs V; Walenbergh SM; van Gorp PJ; Verheyen F; Houben T; Guichot YD; Gijbels MJ; Leitersdorf E; Hofker MH; Lütjohann D; Shiri-Sverdlov R
J Hepatol; 2015 Feb; 62(2):430-6. PubMed ID: 25281859
[TBL] [Abstract][Full Text] [Related]
2. The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice.
Bieghs V; Hendrikx T; van Gorp PJ; Verheyen F; Guichot YD; Walenbergh SM; Jeurissen ML; Gijbels M; Rensen SS; Bast A; Plat J; Kalhan SC; Koek GH; Leitersdorf E; Hofker MH; Lütjohann D; Shiri-Sverdlov R
Gastroenterology; 2013 Jan; 144(1):167-178.e1. PubMed ID: 23041327
[TBL] [Abstract][Full Text] [Related]
3. Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.
Jeurissen ML; Walenbergh SM; Houben T; Hendrikx T; Li J; Oligschlaeger Y; van Gorp PJ; Gijbels MJ; Bitorina A; Nessel I; Radtke F; Vooijs M; Theys J; Shiri-Sverdlov R
PLoS One; 2016; 11(11):e0167199. PubMed ID: 27898698
[TBL] [Abstract][Full Text] [Related]
4. Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
Hendrikx T; Bieghs V; Walenbergh SM; van Gorp PJ; Verheyen F; Jeurissen ML; Steinbusch MM; Vaes N; Binder CJ; Koek GH; Stienstra R; Netea MG; Hofker MH; Shiri-Sverdlov R
PLoS One; 2013; 8(12):e78792. PubMed ID: 24312444
[TBL] [Abstract][Full Text] [Related]
5. Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells.
Bieghs V; Verheyen F; van Gorp PJ; Hendrikx T; Wouters K; Lütjohann D; Gijbels MJ; Febbraio M; Binder CJ; Hofker MH; Shiri-Sverdlov R
PLoS One; 2012; 7(3):e34378. PubMed ID: 22470565
[TBL] [Abstract][Full Text] [Related]
6. LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.
Bieghs V; Van Gorp PJ; Wouters K; Hendrikx T; Gijbels MJ; van Bilsen M; Bakker J; Binder CJ; Lütjohann D; Staels B; Hofker MH; Shiri-Sverdlov R
PLoS One; 2012; 7(1):e30668. PubMed ID: 22295101
[TBL] [Abstract][Full Text] [Related]
7. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis.
Wouters K; van Gorp PJ; Bieghs V; Gijbels MJ; Duimel H; Lütjohann D; Kerksiek A; van Kruchten R; Maeda N; Staels B; van Bilsen M; Shiri-Sverdlov R; Hofker MH
Hepatology; 2008 Aug; 48(2):474-86. PubMed ID: 18666236
[TBL] [Abstract][Full Text] [Related]
8. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis.
Bashiri A; Nesan D; Tavallaee G; Sue-Chue-Lam I; Chien K; Maguire GF; Naples M; Zhang J; Magomedova L; Adeli K; Cummins CL; Ng DS
Biochim Biophys Acta; 2016 Jul; 1861(7):594-605. PubMed ID: 27090939
[TBL] [Abstract][Full Text] [Related]
9. Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling.
Houben T; Bitorina AV; Oligschlaeger Y; Jeurissen ML; Rensen S; Köhler SE; Westerterp M; Lütjohann D; Theys J; Romano A; Plat J; Shiri-Sverdlov R
J Pathol; 2020 Aug; 251(4):429-439. PubMed ID: 32472585
[TBL] [Abstract][Full Text] [Related]
10. Electronegative LDL is linked to high-fat, high-cholesterol diet-induced nonalcoholic steatohepatitis in hamsters.
Lai YS; Yang TC; Chang PY; Chang SF; Ho SL; Chen HL; Lu SC
J Nutr Biochem; 2016 Apr; 30():44-52. PubMed ID: 27012620
[TBL] [Abstract][Full Text] [Related]
11. Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.
Bieghs V; Wouters K; van Gorp PJ; Gijbels MJ; de Winther MP; Binder CJ; Lütjohann D; Febbraio M; Moore KJ; van Bilsen M; Hofker MH; Shiri-Sverdlov R
Gastroenterology; 2010 Jun; 138(7):2477-86, 2486.e1-3. PubMed ID: 20206177
[TBL] [Abstract][Full Text] [Related]
12. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer.
Kimbung S; Chang CY; Bendahl PO; Dubois L; Thompson JW; McDonnell DP; Borgquist S
Endocr Relat Cancer; 2017 Jul; 24(7):339-349. PubMed ID: 28442559
[TBL] [Abstract][Full Text] [Related]
13. RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr
Bijnen M; Beelen N; Wetzels S; Gaar JV; Vroomen M; Wijnands E; Scheijen JL; van de Waarenburg MPH; Gijbels MJ; Cleutjens JP; Biessen EAL; Stehouwer CDA; Schalkwijk CG; Wouters K
Sci Rep; 2018 Oct; 8(1):15256. PubMed ID: 30323247
[TBL] [Abstract][Full Text] [Related]
14. Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation.
Bieghs V; Walenbergh SM; Hendrikx T; van Gorp PJ; Verheyen F; Olde Damink SW; Masclee AA; Koek GH; Hofker MH; Binder CJ; Shiri-Sverdlov R
Liver Int; 2013 Aug; 33(7):1056-61. PubMed ID: 23617943
[TBL] [Abstract][Full Text] [Related]
15. Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, β-cryptoxanthin.
Ni Y; Nagashimada M; Zhan L; Nagata N; Kobori M; Sugiura M; Ogawa K; Kaneko S; Ota T
Endocrinology; 2015 Mar; 156(3):987-99. PubMed ID: 25562616
[TBL] [Abstract][Full Text] [Related]
16. CYP27A1 inhibits bladder cancer cells proliferation by regulating cholesterol homeostasis.
Liang Z; Chen Y; Wang L; Li D; Yang X; Ma G; Wang Y; Li Y; Zhao H; Liang Y; Niu H
Cell Cycle; 2019 Jan; 18(1):34-45. PubMed ID: 30563407
[TBL] [Abstract][Full Text] [Related]
17. Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages.
McGettigan B; McMahan R; Orlicky D; Burchill M; Danhorn T; Francis P; Cheng LL; Golden-Mason L; Jakubzick CV; Rosen HR
Hepatology; 2019 Jul; 70(1):67-83. PubMed ID: 30516830
[TBL] [Abstract][Full Text] [Related]
18. Host CYP27A1 expression is essential for ovarian cancer progression.
He S; Ma L; Baek AE; Vardanyan A; Vembar V; Chen JJ; Nelson AT; Burdette JE; Nelson ER
Endocr Relat Cancer; 2019 Jul; 26(7):659-675. PubMed ID: 31048561
[TBL] [Abstract][Full Text] [Related]
19. Lack of interleukin-1α in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice.
Olteanu S; Kandel-Kfir M; Shaish A; Almog T; Shemesh S; Barshack I; Apte RN; Harats D; Kamari Y
Dig Liver Dis; 2014 May; 46(5):433-9. PubMed ID: 24582082
[TBL] [Abstract][Full Text] [Related]
20. Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis.
Leroux A; Ferrere G; Godie V; Cailleux F; Renoud ML; Gaudin F; Naveau S; Prévot S; Makhzami S; Perlemuter G; Cassard-Doulcier AM
J Hepatol; 2012 Jul; 57(1):141-9. PubMed ID: 22425624
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]