BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 25284778)

  • 1. Increased polyubiquitination and proteasomal degradation of a Munc18-1 disease-linked mutant causes temperature-sensitive defect in exocytosis.
    Martin S; Papadopulos A; Tomatis VM; Sierecki E; Malintan NT; Gormal RS; Giles N; Johnston WA; Alexandrov K; Gambin Y; Collins BM; Meunier FA
    Cell Rep; 2014 Oct; 9(1):206-218. PubMed ID: 25284778
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane.
    Martin S; Tomatis VM; Papadopulos A; Christie MP; Malintan NT; Gormal RS; Sugita S; Martin JL; Collins BM; Meunier FA
    J Cell Sci; 2013 Jun; 126(Pt 11):2353-60. PubMed ID: 23761923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Domain 3a of Munc18-1 plays a crucial role at the priming stage of exocytosis.
    Han GA; Bin NR; Kang SY; Han L; Sugita S
    J Cell Sci; 2013 Jun; 126(Pt 11):2361-71. PubMed ID: 23525015
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Munc18-1 as a key regulator of neurosecretion.
    Han GA; Malintan NT; Collins BM; Meunier FA; Sugita S
    J Neurochem; 2010 Oct; 115(1):1-10. PubMed ID: 20681955
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming.
    Kasula R; Chai YJ; Bademosi AT; Harper CB; Gormal RS; Morrow IC; Hosy E; Collins BM; Choquet D; Papadopulos A; Meunier FA
    J Cell Biol; 2016 Sep; 214(7):847-58. PubMed ID: 27646276
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation.
    Chai YJ; Sierecki E; Tomatis VM; Gormal RS; Giles N; Morrow IC; Xia D; Götz J; Parton RG; Collins BM; Gambin Y; Meunier FA
    J Cell Biol; 2016 Sep; 214(6):705-18. PubMed ID: 27597756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Munc18-1 and the Syntaxin-1 N Terminus Regulate Open-Closed States in a t-SNARE Complex.
    Dawidowski D; Cafiso DS
    Structure; 2016 Mar; 24(3):392-400. PubMed ID: 26876096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Munc18-1 and Munc18-2 proteins modulate beta-cell Ca2+ sensitivity and kinetics of insulin exocytosis differently.
    Mandic SA; Skelin M; Johansson JU; Rupnik MS; Berggren PO; Bark C
    J Biol Chem; 2011 Aug; 286(32):28026-40. PubMed ID: 21690086
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Munc18-1 controls SNARE protein complex assembly during human sperm acrosomal exocytosis.
    Rodríguez F; Zanetti MN; Mayorga LS; Tomes CN
    J Biol Chem; 2012 Dec; 287(52):43825-39. PubMed ID: 23091057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A pivotal role for pro-335 in balancing the dual functions of Munc18-1 domain-3a in regulated exocytosis.
    Han GA; Park S; Bin NR; Jung CH; Kim B; Chandrasegaram P; Matsuda M; Riadi I; Han L; Sugita S
    J Biol Chem; 2014 Nov; 289(48):33617-28. PubMed ID: 25326390
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis.
    Ma L; Rebane AA; Yang G; Xi Z; Kang Y; Gao Y; Zhang Y
    Elife; 2015 Dec; 4():. PubMed ID: 26701912
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Munc18-1 binds directly to the neuronal SNARE complex.
    Dulubova I; Khvotchev M; Liu S; Huryeva I; Südhof TC; Rizo J
    Proc Natl Acad Sci U S A; 2007 Feb; 104(8):2697-702. PubMed ID: 17301226
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of munc18-1 and syntaxin-1A interactive partners in schizophrenia prefrontal cortex: down-regulation of munc18-1a isoform and 75 kDa SNARE complex after antipsychotic treatment.
    Gil-Pisa I; Munarriz-Cuezva E; Ramos-Miguel A; Urigüen L; Meana JJ; García-Sevilla JA
    Int J Neuropsychopharmacol; 2012 Jun; 15(5):573-88. PubMed ID: 21669024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective activation of cognate SNAREpins by Sec1/Munc18 proteins.
    Shen J; Tareste DC; Paumet F; Rothman JE; Melia TJ
    Cell; 2007 Jan; 128(1):183-95. PubMed ID: 17218264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Munc18b regulates core SNARE complex assembly and constitutive exocytosis by interacting with the N-peptide and the closed-conformation C-terminus of syntaxin 3.
    Peng RW; Guetg C; Abellan E; Fussenegger M
    Biochem J; 2010 Nov; 431(3):353-61. PubMed ID: 20695848
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chaperoning of closed syntaxin-3 through Lys46 and Glu59 in domain 1 of Munc18 proteins is indispensable for mast cell exocytosis.
    Bin NR; Jung CH; Kim B; Chandrasegram P; Turlova E; Zhu D; Gaisano HY; Sun HS; Sugita S
    J Cell Sci; 2015 May; 128(10):1946-60. PubMed ID: 25795302
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils.
    Brochetta C; Vita F; Tiwari N; Scandiuzzi L; Soranzo MR; Guérin-Marchand C; Zabucchi G; Blank U
    Biochim Biophys Acta; 2008 Oct; 1783(10):1781-91. PubMed ID: 18588921
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Syntaxin binding mechanism and disease-causing mutations in Munc18-2.
    Hackmann Y; Graham SC; Ehl S; Höning S; Lehmberg K; Aricò M; Owen DJ; Griffiths GM
    Proc Natl Acad Sci U S A; 2013 Nov; 110(47):E4482-91. PubMed ID: 24194549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Sec1/Munc18 Protein Groove Plays a Conserved Role in Interaction with Sec9p/SNAP-25.
    Weber-Boyvat M; Chernov KG; Aro N; Wohlfahrt G; Olkkonen VM; Jäntti J
    Traffic; 2016 Feb; 17(2):131-53. PubMed ID: 26572066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes.
    Zilly FE; Sørensen JB; Jahn R; Lang T
    PLoS Biol; 2006 Oct; 4(10):e330. PubMed ID: 17002520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.