211 related articles for article (PubMed ID: 25288013)
1. Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
Yan T; Gao S; Peng X; Shi J; Xie C; Li Q; Lu L; Wang Y; Zhou F; Liu Z; Hu M
Pharm Res; 2015 Mar; 32(3):1141-57. PubMed ID: 25288013
[TBL] [Abstract][Full Text] [Related]
2. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
Kim JH; Kwon SS; Kong TY; Cheong JC; Kim HS; In MK; Lee HS
Molecules; 2017 Mar; 22(3):. PubMed ID: 28287454
[TBL] [Abstract][Full Text] [Related]
3. Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities.
Xu B; Gao S; Wu B; Yin T; Hu M
J Pharm Biomed Anal; 2014 Jan; 88():180-90. PubMed ID: 24055854
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferases by MAM-2201 in human liver microsomes.
Kong TY; Kim JH; Kwon SS; Cheong JC; Kim HS; In MK; Lee HS
Arch Pharm Res; 2017 Jun; 40(6):727-735. PubMed ID: 28484907
[TBL] [Abstract][Full Text] [Related]
5. Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients.
Yan T; Lu L; Xie C; Chen J; Peng X; Zhu L; Wang Y; Li Q; Shi J; Zhou F; Hu M; Liu Z
Mol Cancer Ther; 2015 Dec; 14(12):2874-86. PubMed ID: 26516155
[TBL] [Abstract][Full Text] [Related]
6. In Vitro Inhibitory Effects of Synthetic Cannabinoid EAM-2201 on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
Kong TY; Kwon SS; Cheong JC; Kim HS; Kim JY; Lee HS
Molecules; 2018 Apr; 23(4):. PubMed ID: 29659506
[TBL] [Abstract][Full Text] [Related]
7. Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
Lu L; Zhou J; Shi J; Peng XJ; Qi XX; Wang Y; Li FY; Zhou FY; Liu L; Liu ZQ
PLoS One; 2015; 10(5):e0127524. PubMed ID: 26010150
[TBL] [Abstract][Full Text] [Related]
8. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
den Braver-Sewradj SP; den Braver MW; Baze A; Decorde J; Fonsi M; Bachellier P; Vermeulen NPE; Commandeur JNM; Richert L; Vos JC
Eur J Pharm Sci; 2017 Nov; 109():96-110. PubMed ID: 28778465
[TBL] [Abstract][Full Text] [Related]
9. Charactering the metabolism of cryptotanshinone by human P450 enzymes and uridine diphosphate glucuronosyltransferases in vitro.
Zeng J; Fan YJ; Tan B; Su HZ; Li Y; Zhang LL; Jiang J; Qiu FR
Acta Pharmacol Sin; 2018 Aug; 39(8):1393-1404. PubMed ID: 29417949
[TBL] [Abstract][Full Text] [Related]
10. Human hepatocarcinoma functional liver cell-4 cell line exhibits high expression of drug-metabolizing enzymes in three-dimensional culture.
Kato R; Shigemoto K; Akiyama H; Ieda A; Ijiri Y; Hayashi T
Biol Pharm Bull; 2014; 37(11):1782-7. PubMed ID: 25366484
[TBL] [Abstract][Full Text] [Related]
11. Absolute quantification of human uridine-diphosphate glucuronosyl transferase (UGT) enzyme isoforms 1A1 and 1A6 by tandem LC-MS.
Fallon JK; Harbourt DE; Maleki SH; Kessler FK; Ritter JK; Smith PC
Drug Metab Lett; 2008 Aug; 2(3):210-22. PubMed ID: 19356096
[TBL] [Abstract][Full Text] [Related]
12. Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics.
Gröer C; Busch D; Patrzyk M; Beyer K; Busemann A; Heidecke CD; Drozdzik M; Siegmund W; Oswald S
J Pharm Biomed Anal; 2014 Nov; 100():393-401. PubMed ID: 25218440
[TBL] [Abstract][Full Text] [Related]
13. Protein quantification of UDP-glucuronosyltransferases 1A1 and 2B7 in human liver microsomes by LC-MS/MS and correlation with glucuronidation activities.
Sato Y; Nagata M; Kawamura A; Miyashita A; Usui T
Xenobiotica; 2012 Sep; 42(9):823-9. PubMed ID: 22435749
[TBL] [Abstract][Full Text] [Related]
14. Coexpression of Human Hepatic Uridine Diphosphate Glucuronosyltransferase Proteins: Implications for Ontogenetic Mechanisms and Isoform Coregulation.
Liu Y; Badée J; Takahashi RH; Schmidt S; Parrott N; Fowler S; Mackenzie PI; Coughtrie MWH; Collier AC
J Clin Pharmacol; 2020 Jun; 60(6):722-733. PubMed ID: 31879975
[TBL] [Abstract][Full Text] [Related]
15. Screening of non-steroidal anti-inflammatory drugs for inhibitory effects on the activities of six UDP-glucuronosyltransferases (UGT1A1, 1A3, 1A4, 1A6, 1A9 and 2B7) using LC-MS/MS.
Joo J; Kim YW; Wu Z; Shin JH; Lee B; Shon JC; Lee EY; Phuc NM; Liu KH
Biopharm Drug Dispos; 2015 May; 36(4):258-64. PubMed ID: 25522350
[TBL] [Abstract][Full Text] [Related]
16. Metabolic interactions of rosmarinic acid with human cytochrome P450 monooxygenases and uridine diphosphate glucuronosyltransferases.
Kim SB; Kim KS; Kim DD; Yoon IS
Biomed Pharmacother; 2019 Feb; 110():111-117. PubMed ID: 30466000
[TBL] [Abstract][Full Text] [Related]
17. Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT).
Knights KM; Rowland A; Miners JO
Br J Clin Pharmacol; 2013 Oct; 76(4):587-602. PubMed ID: 23362865
[TBL] [Abstract][Full Text] [Related]
18. Hepatic biotransformation of non-psychotropic phytocannabinoids and activity screening on cytochromes P450 and UDP-glucuronosyltransferases.
Havlasek J; Vrba J; Zatloukalova M; Papouskova B; Modriansky M; Storch J; Vacek J
Toxicol Appl Pharmacol; 2023 Oct; 476():116654. PubMed ID: 37574147
[TBL] [Abstract][Full Text] [Related]
19. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
Chen A; Zhou X; Cheng Y; Tang S; Liu M; Wang X
Toxicol Lett; 2018 Oct; 295():379-389. PubMed ID: 30036684
[TBL] [Abstract][Full Text] [Related]
20. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.
Hanioka N; Ozawa S; Jinno H; Ando M; Saito Y; Sawada J
Xenobiotica; 2001 Oct; 31(10):687-99. PubMed ID: 11695848
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]