These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 25288794)

  • 1. Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.
    Koharudin LM; Wu Y; DeLucia M; Mehrens J; Gronenborn AM; Ahn J
    J Biol Chem; 2014 Nov; 289(47):32617-27. PubMed ID: 25288794
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of allosteric activation of SAMHD1 by dGTP.
    Ji X; Wu Y; Yan J; Mehrens J; Yang H; DeLucia M; Hao C; Gronenborn AM; Skowronski J; Ahn J; Xiong Y
    Nat Struct Mol Biol; 2013 Nov; 20(11):1304-9. PubMed ID: 24141705
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1).
    Miazzi C; Ferraro P; Pontarin G; Rampazzo C; Reichard P; Bianchi V
    J Biol Chem; 2014 Jun; 289(26):18339-46. PubMed ID: 24828500
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of cellular dNTP regulation by SAMHD1.
    Ji X; Tang C; Zhao Q; Wang W; Xiong Y
    Proc Natl Acad Sci U S A; 2014 Oct; 111(41):E4305-14. PubMed ID: 25267621
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
    Goldstone DC; Ennis-Adeniran V; Hedden JJ; Groom HC; Rice GI; Christodoulou E; Walker PA; Kelly G; Haire LF; Yap MW; de Carvalho LP; Stoye JP; Crow YJ; Taylor IA; Webb M
    Nature; 2011 Nov; 480(7377):379-82. PubMed ID: 22056990
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state.
    Hansen EC; Seamon KJ; Cravens SL; Stivers JT
    Proc Natl Acad Sci U S A; 2014 May; 111(18):E1843-51. PubMed ID: 24753578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein.
    Li Y; Kong J; Peng X; Hou W; Qin X; Yu XF
    J Biol Chem; 2015 Dec; 290(49):29428-37. PubMed ID: 26438820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GTP is the primary activator of the anti-HIV restriction factor SAMHD1.
    Amie SM; Bambara RA; Kim B
    J Biol Chem; 2013 Aug; 288(35):25001-25006. PubMed ID: 23880768
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Substrate Specificity of SAMHD1 Triphosphohydrolase Activity Is Controlled by Deoxyribonucleoside Triphosphates and Phosphorylation at Thr592.
    Jang S; Zhou X; Ahn J
    Biochemistry; 2016 Oct; 55(39):5635-5646. PubMed ID: 27588835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R
    Morris ER; Kunzelmann S; Caswell SJ; Purkiss AG; Kelly G; Taylor IA
    Biochemistry; 2021 Jun; 60(21):1682-1698. PubMed ID: 33988981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric Activation of SAMHD1 Protein by Deoxynucleotide Triphosphate (dNTP)-dependent Tetramerization Requires dNTP Concentrations That Are Similar to dNTP Concentrations Observed in Cycling T Cells.
    Wang Z; Bhattacharya A; Villacorta J; Diaz-Griffero F; Ivanov DN
    J Biol Chem; 2016 Oct; 291(41):21407-21413. PubMed ID: 27566548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
    Zhu C; Gao W; Zhao K; Qin X; Zhang Y; Peng X; Zhang L; Dong Y; Zhang W; Li P; Wei W; Gong Y; Yu XF
    Nat Commun; 2013; 4():2722. PubMed ID: 24217394
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse.
    Bloch N; Gläsker S; Sitaram P; Hofmann H; Shepard CN; Schultz ML; Kim B; Landau NR
    J Biol Chem; 2017 Jan; 292(3):1068-1080. PubMed ID: 27920203
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
    Zhu CF; Wei W; Peng X; Dong YH; Gong Y; Yu XF
    Acta Crystallogr D Biol Crystallogr; 2015 Mar; 71(Pt 3):516-24. PubMed ID: 25760601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations.
    Patra KK; Bhattacharya A; Bhattacharya S
    Proteins; 2017 Jul; 85(7):1266-1275. PubMed ID: 28321930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
    Klemm BP; Sikkema AP; Hsu AL; Horng JC; Hall TMT; Borgnia MJ; Schaaper RM
    J Biol Chem; 2022 Jul; 298(7):102073. PubMed ID: 35643313
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity.
    Seamon KJ; Sun Z; Shlyakhtenko LS; Lyubchenko YL; Stivers JT
    Nucleic Acids Res; 2015 Jul; 43(13):6486-99. PubMed ID: 26101257
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
    Barnes CO; Wu Y; Song J; Lin G; Baxter EL; Brewster AS; Nagarajan V; Holmes A; Soltis SM; Sauter NK; Ahn J; Cohen AE; Calero G
    Proc Natl Acad Sci U S A; 2019 May; 116(19):9333-9339. PubMed ID: 31019074
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanisms of allosteric activation and inhibition of the deoxyribonucleoside triphosphate triphosphohydrolase from Enterococcus faecalis.
    Vorontsov II; Wu Y; DeLucia M; Minasov G; Mehrens J; Shuvalova L; Anderson WF; Ahn J
    J Biol Chem; 2014 Jan; 289(5):2815-24. PubMed ID: 24338016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
    Wu Y; Koharudin LMI; Mehrens J; DeLucia M; Byeon CH; Byeon IL; Calero G; Ahn J; Gronenborn AM
    J Biol Chem; 2015 Jul; 290(29):17935-17945. PubMed ID: 26045556
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.