These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 25290579)

  • 1. Fluorinated aromatic amino acids are sensitive 19F NMR probes for bromodomain-ligand interactions.
    Mishra NK; Urick AK; Ember SW; Schönbrunn E; Pomerantz WC
    ACS Chem Biol; 2014 Dec; 9(12):2755-60. PubMed ID: 25290579
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
    Yu Z; Ku AF; Anglin JL; Sharma R; Ucisik MN; Faver JC; Li F; Nyshadham P; Simmons N; Sharma KL; Nagarajan S; Riehle K; Kaur G; Sankaran B; Storl-Desmond M; Palmer SS; Young DW; Kim C; Matzuk MM
    Proc Natl Acad Sci U S A; 2021 Mar; 118(9):. PubMed ID: 33637650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules.
    Urick AK; Hawk LM; Cassel MK; Mishra NK; Liu S; Adhikari N; Zhang W; dos Santos CO; Hall JL; Pomerantz WC
    ACS Chem Biol; 2015 Oct; 10(10):2246-56. PubMed ID: 26158404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SAR by (Protein-Observed)
    Divakaran A; Kirberger SE; Pomerantz WCK
    Acc Chem Res; 2019 Dec; 52(12):3407-3418. PubMed ID: 31718149
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulated induced proximity targeting chimeras-RIPTACs-A heterobifunctional small molecule strategy for cancer selective therapies.
    Raina K; Forbes CD; Stronk R; Rappi JP; Eastman KJ; Zaware N; Yu X; Li H; Bhardwaj A; Gerritz SW; Forgione M; Hundt A; King MP; Posner ZM; Correia AD; McGovern A; Puleo DE; Chenard R; Mousseau JJ; Vergara JI; Garvin E; Macaluso J; Martin M; Bassoli K; Jones K; Garcia M; Howard K; Yaggi M; Smith LM; Chen JM; Mayfield AB; De Leon CA; Hines J; Kayser-Bricker KJ; Crews CM
    Cell Chem Biol; 2024 Aug; 31(8):1490-1502.e42. PubMed ID: 39116881
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes.
    Baud MGJ; Lin-Shiao E; Cardote T; Tallant C; Pschibul A; Chan KH; Zengerle M; Garcia JR; Kwan TT; Ferguson FM; Ciulli A
    Science; 2014 Oct; 346(6209):638-641. PubMed ID: 25323695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign.
    Colarusso E; Gazzillo E; Boccia E; Terracciano S; Bruno I; Bifulco G; Chini MG; Lauro G
    Molecules; 2024 Aug; 29(17):. PubMed ID: 39274873
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclin-dependent kinase inhibitor dinaciclib interacts with the acetyl-lysine recognition site of bromodomains.
    Martin MP; Olesen SH; Georg GI; Schönbrunn E
    ACS Chem Biol; 2013 Nov; 8(11):2360-5. PubMed ID: 24007471
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Bead-Based Proximity Assay for BRD4 Ligand Discovery.
    Roberts JM; Bradner JE
    Curr Protoc Chem Biol; 2015 Dec; 7(4):263-278. PubMed ID: 26629616
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins.
    Kalra P; McGraw L; Kimbrough JR; Pandey AK; Solberg J; Cui H; Divakaran A; John K; Hawkinson JE; Pomerantz WCK
    ACS Chem Biol; 2020 Nov; 15(11):3038-3049. PubMed ID: 33138352
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
    Ycas PD; Zahid H; Chan A; Olson NM; Johnson JA; Talluri SK; Schonbrunn E; Pomerantz WCK
    Org Biomol Chem; 2020 Jul; 18(27):5174-5182. PubMed ID: 32588860
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization.
    Xiong L; Mao X; Guo Y; Zhou Y; Chen M; Chen P; Yang S; Li L
    Biochem Biophys Res Commun; 2021 Mar; 545():125-131. PubMed ID: 33548625
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A.
    Williams FP; Milbradt AG; Embrey KJ; Bobby R
    PLoS One; 2016; 11(4):e0154607. PubMed ID: 27128490
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor.
    Kirberger SE; Ycas PD; Johnson JA; Chen C; Ciccone MF; Woo RWL; Urick AK; Zahid H; Shi K; Aihara H; McAllister SD; Kashani-Sabet M; Shi J; Dickson A; Dos Santos CO; Pomerantz WCK
    Org Biomol Chem; 2019 Feb; 17(7):2020-2027. PubMed ID: 30706071
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Opportunity knocks for uncovering the new function of an understudied nucleosome remodeling complex member, the bromodomain PHD finger transcription factor, BPTF.
    Zahid H; Olson NM; Pomerantz WCK
    Curr Opin Chem Biol; 2021 Aug; 63():57-67. PubMed ID: 33706239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein-observed (19)F-NMR for fragment screening, affinity quantification and druggability assessment.
    Gee CT; Arntson KE; Urick AK; Mishra NK; Hawk LM; Wisniewski AJ; Pomerantz WC
    Nat Protoc; 2016 Aug; 11(8):1414-27. PubMed ID: 27414758
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined Protein- and Ligand-Observed NMR Workflow to Screen Fragment Cocktails against Multiple Proteins: A Case Study Using Bromodomains.
    Johnson JA; Olson NM; Tooker MJ; Bur SK; Pomerantz WCK
    Molecules; 2020 Aug; 25(17):. PubMed ID: 32872491
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.
    Olp MD; Zhu N; Smith BC
    Biochemistry; 2017 Oct; 56(41):5485-5495. PubMed ID: 28945351
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
    Lambert JP; Picaud S; Fujisawa T; Hou H; Savitsky P; Uusküla-Reimand L; Gupta GD; Abdouni H; Lin ZY; Tucholska M; Knight JDR; Gonzalez-Badillo B; St-Denis N; Newman JA; Stucki M; Pelletier L; Bandeira N; Wilson MD; Filippakopoulos P; Gingras AC
    Mol Cell; 2019 Feb; 73(3):621-638.e17. PubMed ID: 30554943
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.
    Chattopadhyay D; Swingle MR; Salter EA; Wood E; D'Arcy B; Zivanov C; Abney K; Musiyenko A; Rusin SF; Kettenbach A; Yet L; Schroeder CE; Golden JE; Dunham WH; Gingras AC; Banerjee S; Forbes D; Wierzbicki A; Honkanen RE
    Biochem Pharmacol; 2016 Jun; 109():14-26. PubMed ID: 27002182
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.