467 related articles for article (PubMed ID: 25295789)
1. CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance.
Raichur S; Wang ST; Chan PW; Li Y; Ching J; Chaurasia B; Dogra S; Öhman MK; Takeda K; Sugii S; Pewzner-Jung Y; Futerman AH; Summers SA
Cell Metab; 2014 Oct; 20(4):687-95. PubMed ID: 25295789
[TBL] [Abstract][Full Text] [Related]
2. Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance.
Turpin SM; Nicholls HT; Willmes DM; Mourier A; Brodesser S; Wunderlich CM; Mauer J; Xu E; Hammerschmidt P; Brönneke HS; Trifunovic A; LoSasso G; Wunderlich FT; Kornfeld JW; Blüher M; Krönke M; Brüning JC
Cell Metab; 2014 Oct; 20(4):678-86. PubMed ID: 25295788
[TBL] [Abstract][Full Text] [Related]
3. The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach.
Raichur S; Brunner B; Bielohuby M; Hansen G; Pfenninger A; Wang B; Bruning JC; Larsen PJ; Tennagels N
Mol Metab; 2019 Mar; 21():36-50. PubMed ID: 30655217
[TBL] [Abstract][Full Text] [Related]
4. Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases.
Kim YR; Lee EJ; Shin KO; Kim MH; Pewzner-Jung Y; Lee YM; Park JW; Futerman AH; Park WJ
Exp Mol Med; 2019 Nov; 51(11):1-16. PubMed ID: 31676768
[TBL] [Abstract][Full Text] [Related]
5. Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis.
Stiban J; Perera M
Biochim Biophys Acta; 2015 Feb; 1848(2):561-7. PubMed ID: 25462172
[TBL] [Abstract][Full Text] [Related]
6. Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length.
Park WJ; Park JW; Merrill AH; Storch J; Pewzner-Jung Y; Futerman AH
Biochim Biophys Acta; 2014 Dec; 1841(12):1754-66. PubMed ID: 25241943
[TBL] [Abstract][Full Text] [Related]
7. Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides.
Cinar R; Godlewski G; Liu J; Tam J; Jourdan T; Mukhopadhyay B; Harvey-White J; Kunos G
Hepatology; 2014 Jan; 59(1):143-53. PubMed ID: 23832510
[TBL] [Abstract][Full Text] [Related]
8. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
Tirodkar TS; Lu P; Bai A; Scheffel MJ; Gencer S; Garrett-Mayer E; Bielawska A; Ogretmen B; Voelkel-Johnson C
J Biol Chem; 2015 May; 290(21):13157-67. PubMed ID: 25839235
[TBL] [Abstract][Full Text] [Related]
9. Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.
Sassa T; Hirayama T; Kihara A
J Biol Chem; 2016 Apr; 291(14):7477-87. PubMed ID: 26887952
[TBL] [Abstract][Full Text] [Related]
10. Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization.
Park WJ; Park JW; Erez-Roman R; Kogot-Levin A; Bame JR; Tirosh B; Saada A; Merrill AH; Pewzner-Jung Y; Futerman AH
J Biol Chem; 2013 Oct; 288(43):30904-16. PubMed ID: 24019516
[TBL] [Abstract][Full Text] [Related]
11. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer.
Lee WK; Maaß M; Quach A; Poscic N; Prangley H; Pallott EC; Kim JL; Pierce JS; Ogretmen B; Futerman AH; Thévenod F
J Biol Chem; 2022 Feb; 298(2):101492. PubMed ID: 34915026
[TBL] [Abstract][Full Text] [Related]
12. Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain.
Zigdon H; Kogot-Levin A; Park JW; Goldschmidt R; Kelly S; Merrill AH; Scherz A; Pewzner-Jung Y; Saada A; Futerman AH
J Biol Chem; 2013 Feb; 288(7):4947-56. PubMed ID: 23283968
[TBL] [Abstract][Full Text] [Related]
13. Hepatic inflammatory cytokine production can be regulated by modulating sphingomyelinase and ceramide synthase 6.
Kim MH; Ahn HK; Lee EJ; Kim SJ; Kim YR; Park JW; Park WJ
Int J Mol Med; 2017 Feb; 39(2):453-462. PubMed ID: 28035360
[TBL] [Abstract][Full Text] [Related]
14. Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species.
Montgomery MK; Brown SH; Lim XY; Fiveash CE; Osborne B; Bentley NL; Braude JP; Mitchell TW; Coster AC; Don AS; Cooney GJ; Schmitz-Peiffer C; Turner N
Biochim Biophys Acta; 2016 Nov; 1861(11):1828-1839. PubMed ID: 27591968
[TBL] [Abstract][Full Text] [Related]
15. The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.
Hartmann D; Wegner MS; Wanger RA; Ferreirós N; Schreiber Y; Lucks J; Schiffmann S; Geisslinger G; Grösch S
Int J Biochem Cell Biol; 2013 Jul; 45(7):1195-203. PubMed ID: 23538298
[TBL] [Abstract][Full Text] [Related]
16. Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate-induced colitis in mice due to increased intestinal permeability.
Kim YR; Volpert G; Shin KO; Kim SY; Shin SH; Lee Y; Sung SH; Lee YM; Ahn JH; Pewzner-Jung Y; Park WJ; Futerman AH; Park JW
J Cell Mol Med; 2017 Dec; 21(12):3565-3578. PubMed ID: 28699686
[TBL] [Abstract][Full Text] [Related]
17. Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.
Gosejacob D; Jäger PS; Vom Dorp K; Frejno M; Carstensen AC; Köhnke M; Degen J; Dörmann P; Hoch M
J Biol Chem; 2016 Mar; 291(13):6989-7003. PubMed ID: 26853464
[TBL] [Abstract][Full Text] [Related]
18. Ceramide synthase 2-C
Zhang X; Sakamoto W; Canals D; Ishibashi M; Matsuda M; Nishida K; Toyoshima M; Shigeta S; Taniguchi M; Senkal CE; Okazaki T; Yaegashi N; Hannun YA; Nabe T; Kitatani K
FASEB J; 2021 Feb; 35(2):e21287. PubMed ID: 33423335
[TBL] [Abstract][Full Text] [Related]
19. Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide.
Yamaji T; Horie A; Tachida Y; Sakuma C; Suzuki Y; Kushi Y; Hanada K
Int J Mol Sci; 2016 Oct; 17(10):. PubMed ID: 27775668
[TBL] [Abstract][Full Text] [Related]
20. Modulation of ceramide synthase activity via dimerization.
Laviad EL; Kelly S; Merrill AH; Futerman AH
J Biol Chem; 2012 Jun; 287(25):21025-33. PubMed ID: 22539345
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]