These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 25297465)

  • 1. The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism.
    Bachstetter AD; Xing B; Van Eldik LJ
    J Neuroinflammation; 2014 Oct; 11():175. PubMed ID: 25297465
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).
    Bachstetter AD; Xing B; de Almeida L; Dimayuga ER; Watterson DM; Van Eldik LJ
    J Neuroinflammation; 2011 Jul; 8():79. PubMed ID: 21733175
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The p38α MAPK regulates microglial responsiveness to diffuse traumatic brain injury.
    Bachstetter AD; Rowe RK; Kaneko M; Goulding D; Lifshitz J; Van Eldik LJ
    J Neurosci; 2013 Apr; 33(14):6143-53. PubMed ID: 23554495
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα.
    Xing B; Bachstetter AD; Van Eldik LJ
    Mol Neurodegener; 2011 Dec; 6():84. PubMed ID: 22185458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deficiency in p38β MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models.
    Xing B; Bachstetter AD; Van Eldik LJ
    PLoS One; 2013; 8(2):e56852. PubMed ID: 23457629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.
    Docena G; Rovedatti L; Kruidenier L; Fanning A; Leakey NA; Knowles CH; Lee K; Shanahan F; Nally K; McLean PG; Di Sabatino A; MacDonald TT
    Clin Exp Immunol; 2010 Oct; 162(1):108-15. PubMed ID: 20731675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Target engagement analysis and link to pharmacodynamic endpoint for a novel class of CNS-penetrant and efficacious p38α MAPK inhibitors.
    Bachstetter AD; Watterson DM; Van Eldik LJ
    J Neuroimmune Pharmacol; 2014 Sep; 9(4):454-60. PubMed ID: 24789302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Macrophage p38α promotes nutritional steatohepatitis through M1 polarization.
    Zhang X; Fan L; Wu J; Xu H; Leung WY; Fu K; Wu J; Liu K; Man K; Yang X; Han J; Ren J; Yu J
    J Hepatol; 2019 Jul; 71(1):163-174. PubMed ID: 30914267
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation.
    Kang YJ; Chen J; Otsuka M; Mols J; Ren S; Wang Y; Han J
    J Immunol; 2008 Apr; 180(7):5075-82. PubMed ID: 18354233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deletion of p38α MAPK in microglia blunts trauma-induced inflammatory responses in mice.
    Morganti JM; Goulding DS; Van Eldik LJ
    J Neuroinflammation; 2019 May; 16(1):98. PubMed ID: 31077217
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin.
    Katholnig K; Kaltenecker CC; Hayakawa H; Rosner M; Lassnig C; Zlabinger GJ; Gaestel M; Müller M; Hengstschläger M; Hörl WH; Park JM; Säemann MD; Weichhart T
    J Immunol; 2013 Feb; 190(4):1519-27. PubMed ID: 23315073
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of a constitutively active p38α mutant in mice causes early death, anemia, and accumulation of immunosuppressive cells.
    Darlyuk-Saadon I; Heng CKM; Bai C; Gilad N; Yu WP; Meng Huang Mok M; Wong WSF; Engelberg D
    FEBS J; 2021 Jul; 288(13):3978-3999. PubMed ID: 33410203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase.
    Guo X; Gerl RE; Schrader JW
    J Biol Chem; 2003 Jun; 278(25):22237-42. PubMed ID: 12637577
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The p38alpha mitogen-activated protein kinase as a central nervous system drug discovery target.
    Borders AS; de Almeida L; Van Eldik LJ; Watterson DM
    BMC Neurosci; 2008 Dec; 9 Suppl 2(Suppl 2):S12. PubMed ID: 19090985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular mechanism of lipopolysaccharide-induced SOCS-3 gene expression in macrophages and microglia.
    Qin H; Roberts KL; Niyongere SA; Cong Y; Elson CO; Benveniste EN
    J Immunol; 2007 Nov; 179(9):5966-76. PubMed ID: 17947670
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Morphine mediates a proinflammatory phenotype via μ-opioid receptor-PKCɛ-Akt-ERK1/2 signaling pathway in activated microglial cells.
    Merighi S; Gessi S; Varani K; Fazzi D; Stefanelli A; Borea PA
    Biochem Pharmacol; 2013 Aug; 86(4):487-96. PubMed ID: 23796752
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes.
    Lo U; Selvaraj V; Plane JM; Chechneva OV; Otsu K; Deng W
    Sci Rep; 2014 Dec; 4():7405. PubMed ID: 25502009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-inflammatory roles of p38α MAPK in macrophages are context dependent and require IL-10.
    Raza A; Crothers JW; McGill MM; Mawe GM; Teuscher C; Krementsov DN
    J Leukoc Biol; 2017 Nov; 102(5):1219-1227. PubMed ID: 28877953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Triggering Receptor Expressed on Myeloid Cells 2 Overexpression Inhibits Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Microglia.
    Zhang X; Yan F; Cui J; Wu Y; Luan H; Yin M; Zhao Z; Feng J; Zhang J
    Mediators Inflamm; 2017; 2017():9340610. PubMed ID: 29180839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS.
    Chung SH; Biswas S; Selvaraj V; Liu XB; Sohn J; Jiang P; Chen C; Chmilewsky F; Marzban H; Horiuchi M; Pleasure DE; Deng W
    Cell Death Dis; 2015 May; 6(5):e1748. PubMed ID: 25950478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.