BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 25298408)

  • 61. TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells.
    Magini A; Polchi A; Di Meo D; Mariucci G; Sagini K; De Marco F; Cassano T; Giovagnoli S; Dolcetta D; Emiliani C
    Hum Mol Genet; 2017 Sep; 26(17):3303-3312. PubMed ID: 28637240
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Proteomic analysis of murine Tsc1-deficient neural stem progenitor cells.
    Chiaradia E; Miller I; Renzone G; Tognoloni A; Polchi A; De Marco F; Tancini B; Scaloni A; Magini A
    J Proteomics; 2023 Jul; 283-284():104928. PubMed ID: 37207814
    [TBL] [Abstract][Full Text] [Related]  

  • 63. mTORC2 is required for proliferation and survival of TSC2-null cells.
    Goncharova EA; Goncharov DA; Li H; Pimtong W; Lu S; Khavin I; Krymskaya VP
    Mol Cell Biol; 2011 Jun; 31(12):2484-98. PubMed ID: 21482669
    [TBL] [Abstract][Full Text] [Related]  

  • 64. TSC1 controls distribution of actin fibers through its effect on function of Rho family of small GTPases and regulates cell migration and polarity.
    Ohsawa M; Kobayashi T; Okura H; Igarashi T; Mizuguchi M; Hino O
    PLoS One; 2013; 8(1):e54503. PubMed ID: 23355874
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
    Di Nardo A; Kramvis I; Cho N; Sadowski A; Meikle L; Kwiatkowski DJ; Sahin M
    J Neurosci; 2009 May; 29(18):5926-37. PubMed ID: 19420259
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
    Tanwar PS; Kaneko-Tarui T; Zhang L; Tanaka Y; Crum CP; Teixeira JM
    PLoS Genet; 2012; 8(8):e1002906. PubMed ID: 22916036
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex.
    Jin F; Jiang K; Ji S; Wang L; Ni Z; Huang F; Li C; Chen R; Zhang H; Hu Z; Zha X
    Hum Mol Genet; 2017 Jan; 26(2):407-419. PubMed ID: 28013293
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Regulation of mTORC1 signaling by pH.
    Balgi AD; Diering GH; Donohue E; Lam KK; Fonseca BD; Zimmerman C; Numata M; Roberge M
    PLoS One; 2011; 6(6):e21549. PubMed ID: 21738705
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion.
    Martin TD; Chen XW; Kaplan RE; Saltiel AR; Walker CL; Reiner DJ; Der CJ
    Mol Cell; 2014 Jan; 53(2):209-20. PubMed ID: 24389102
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
    Huang J; Wu S; Wu CL; Manning BD
    Cancer Res; 2009 Aug; 69(15):6107-14. PubMed ID: 19602587
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy.
    Valianou M; Cox AM; Pichette B; Hartley S; Paladhi UR; Astrinidis A
    Cell Cycle; 2015; 14(3):399-407. PubMed ID: 25565629
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex.
    Howell JJ; Hellberg K; Turner M; Talbott G; Kolar MJ; Ross DS; Hoxhaj G; Saghatelian A; Shaw RJ; Manning BD
    Cell Metab; 2017 Feb; 25(2):463-471. PubMed ID: 28089566
    [TBL] [Abstract][Full Text] [Related]  

  • 73. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
    Menon S; Dibble CC; Talbott G; Hoxhaj G; Valvezan AJ; Takahashi H; Cantley LC; Manning BD
    Cell; 2014 Feb; 156(4):771-85. PubMed ID: 24529379
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin.
    Yang J; Kalogerou M; Gallacher J; Sampson JR; Shen MH
    Eur J Cancer; 2013 Apr; 49(6):1479-90. PubMed ID: 23228442
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
    Malhowski AJ; Hira H; Bashiruddin S; Warburton R; Goto J; Robert B; Kwiatkowski DJ; Finlay GA
    Hum Mol Genet; 2011 Apr; 20(7):1290-305. PubMed ID: 21212099
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.
    Johnson CE; Hunt DK; Wiltshire M; Herbert TP; Sampson JR; Errington RJ; Davies DM; Tee AR
    Mol Oncol; 2015 Mar; 9(3):675-88. PubMed ID: 25498902
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy.
    Huang H; Kang R; Wang J; Luo G; Yang W; Zhao Z
    Autophagy; 2013 Feb; 9(2):175-95. PubMed ID: 23169238
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Tuberous sclerosis complex and DNA repair.
    Habib SL
    Adv Exp Med Biol; 2010; 685():84-94. PubMed ID: 20687497
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Autophagy: an 'Achilles' heel of tumorigenesis in TSC and LAM.
    Yu J; Parkhitko A; Henske EP
    Autophagy; 2011 Nov; 7(11):1400-1. PubMed ID: 21997371
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.