248 related articles for article (PubMed ID: 25299681)
1. Identification of novel PTP1B inhibitors by pharmacophore based virtual screening, scaffold hopping and docking.
Balaramnavar VM; Srivastava R; Rahuja N; Gupta S; Rawat AK; Varshney S; Chandasana H; Chhonker YS; Doharey PK; Kumar S; Gautam S; Srivastava SP; Bhatta RS; Saxena JK; Gaikwad AN; Srivastava AK; Saxena AK
Eur J Med Chem; 2014 Nov; 87():578-94. PubMed ID: 25299681
[TBL] [Abstract][Full Text] [Related]
2. Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors.
Li X; Xu Q; Li C; Luo J; Li X; Wang L; Jiang B; Shi D
Eur J Med Chem; 2019 Mar; 166():178-185. PubMed ID: 30711829
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib.
Liu JZ; Zhang SE; Nie F; Yang Y; Tang YB; Yin W; Tian JY; Ye F; Xiao Z
Bioorg Med Chem Lett; 2013 Dec; 23(23):6217-22. PubMed ID: 24148325
[TBL] [Abstract][Full Text] [Related]
4. The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation.
Ma Y; Jin YY; Wang YL; Wang RL; Lu XH; Kong DX; Xu WR
Chem Biol Drug Des; 2014 Jun; 83(6):697-709. PubMed ID: 24418013
[TBL] [Abstract][Full Text] [Related]
5. Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes.
Sun W; Zhang B; Zheng H; Zhuang C; Li X; Lu X; Quan C; Dong Y; Zheng Z; Xiu Z
Life Sci; 2017 Jan; 169():52-64. PubMed ID: 27871946
[TBL] [Abstract][Full Text] [Related]
6. Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice.
Liu ZQ; Liu T; Chen C; Li MY; Wang ZY; Chen RS; Wei GX; Wang XY; Luo DQ
Toxicol Appl Pharmacol; 2015 May; 285(1):61-70. PubMed ID: 25796170
[TBL] [Abstract][Full Text] [Related]
7. Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice.
Sun J; Fu X; Liu Y; Wang Y; Huo B; Guo Y; Gao X; Li W; Hu X
Drug Des Devel Ther; 2015; 9():6327-42. PubMed ID: 26674084
[TBL] [Abstract][Full Text] [Related]
8. 2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation.
Morishita K; Shoji Y; Fukui M; Ito Y; Kitao T; Ozawa SI; Hirono S; Shirahase H
Chem Pharm Bull (Tokyo); 2018; 66(12):1131-1152. PubMed ID: 30504630
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, SAR and docking studies of substituted aryl phenylthiazolyl phenylcarboxamide as potential protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Varshney K; Gupta AK; Rawat A; Srivastava R; Mishra A; Saxena M; Srivastava AK; Jain S; Saxena AK
Chem Biol Drug Des; 2019 Jul; 94(1):1378-1389. PubMed ID: 30903642
[TBL] [Abstract][Full Text] [Related]
10. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
Rao GS; Ramachandran MV; Bajaj JS
J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of 2,4,6-trihydroxychalcone derivatives as novel protein tyrosine phosphatase 1B inhibitors.
Sun LP; Gao LX; Ma WP; Nan FJ; Li J; Piao HR
Chem Biol Drug Des; 2012 Oct; 80(4):584-90. PubMed ID: 22805439
[TBL] [Abstract][Full Text] [Related]
12. α-Methyl artoflavanocoumarin from Juniperus chinensis exerts anti-diabetic effects by inhibiting PTP1B and activating the PI3K/Akt signaling pathway in insulin-resistant HepG2 cells.
Jung HJ; Seong SH; Ali MY; Min BS; Jung HA; Choi JS
Arch Pharm Res; 2017 Dec; 40(12):1403-1413. PubMed ID: 29177868
[TBL] [Abstract][Full Text] [Related]
13. Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice.
Jiang B; Guo S; Shi D; Guo C; Wang T
Eur J Med Chem; 2013 Jun; 64():129-36. PubMed ID: 23644196
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors.
Tang YB; Lu D; Chen Z; Hu C; Yang Y; Tian JY; Ye F; Wu L; Zhang ZY; Xiao Z
Bioorg Med Chem Lett; 2013 Apr; 23(8):2313-8. PubMed ID: 23499238
[TBL] [Abstract][Full Text] [Related]
15. Canthinone alkaloids are novel protein tyrosine phosphatase 1B inhibitors.
Sasaki T; Li W; Higai K; Koike K
Bioorg Med Chem Lett; 2015 May; 25(9):1979-81. PubMed ID: 25819098
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy.
Chen YT; Tang CL; Ma WP; Gao LX; Wei Y; Zhang W; Li JY; Li J; Nan FJ
Eur J Med Chem; 2013 Nov; 69():399-412. PubMed ID: 24090912
[TBL] [Abstract][Full Text] [Related]
17. Discovery of Bisindole as a Novel Scaffold for Protein Tyrosine Phosphatase 1B Inhibitors.
Jing C; Li Z; Jia K; Chen C; Liu X; Wang B; Hu W; Li J; Zhu T; Dong S
Arch Pharm (Weinheim); 2017 Jan; 350(1):. PubMed ID: 28029177
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
He HB; Gao LX; Deng QF; Ma WP; Tang CL; Qiu WW; Tang J; Li JY; Li J; Yang F
Bioorg Med Chem Lett; 2012 Dec; 22(23):7237-42. PubMed ID: 23067554
[TBL] [Abstract][Full Text] [Related]
19. Discovery and biological evaluation of novel dual PTP1B and ACP1 inhibitors for the treatment of insulin resistance.
Feng B; Zhang J; Liu Z; Xu Y; Hu H
Bioorg Med Chem; 2024 Jan; 97():117545. PubMed ID: 38070352
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.
Ottanà R; Maccari R; Mortier J; Caselli A; Amuso S; Camici G; Rotondo A; Wolber G; Paoli P
Eur J Med Chem; 2014 Jan; 71():112-27. PubMed ID: 24287560
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
