These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 25305014)

  • 21. Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation.
    Mirmira RG; Tager HS
    J Biol Chem; 1989 Apr; 264(11):6349-54. PubMed ID: 2649499
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural determinants of ligand recognition by type I insulin-like growth factor receptors: use of semisynthetic insulin analog probes.
    Cara JF; Nakagawa SH; Tager HS
    Endocrinology; 1988 Jun; 122(6):2881-7. PubMed ID: 2967179
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Protective hinge in insulin opens to enable its receptor engagement.
    Menting JG; Yang Y; Chan SJ; Phillips NB; Smith BJ; Whittaker J; Wickramasinghe NP; Whittaker LJ; Pandyarajan V; Wan ZL; Yadav SP; Carroll JM; Strokes N; Roberts CT; Ismail-Beigi F; Milewski W; Steiner DF; Chauhan VS; Ward CW; Weiss MA; Lawrence MC
    Proc Natl Acad Sci U S A; 2014 Aug; 111(33):E3395-404. PubMed ID: 25092300
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Decoding the cryptic active conformation of a protein by synthetic photoscanning: insulin inserts a detachable arm between receptor domains.
    Xu B; Huang K; Chu YC; Hu SQ; Nakagawa S; Wang S; Wang RY; Whittaker J; Katsoyannis PG; Weiss MA
    J Biol Chem; 2009 May; 284(21):14597-608. PubMed ID: 19321435
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Nonlocal structural perturbations in a mutant human insulin: sequential resonance assignment and 13C-isotope-aided 2D-NMR studies of [PheB24-->Gly]insulin with implications for receptor recognition.
    Hua QX; Shoelson SE; Weiss MA
    Biochemistry; 1992 Dec; 31(47):11940-51. PubMed ID: 1445924
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Biophysical optimization of a therapeutic protein by nonstandard mutagenesis: studies of an iodo-insulin derivative.
    Pandyarajan V; Phillips NB; Cox GP; Yang Y; Whittaker J; Ismail-Beigi F; Weiss MA
    J Biol Chem; 2014 Aug; 289(34):23367-81. PubMed ID: 24993826
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice.
    Huang K; Chan SJ; Hua QX; Chu YC; Wang RY; Klaproth B; Jia W; Whittaker J; De Meyts P; Nakagawa SH; Steiner DF; Katsoyannis PG; Weiss MA
    J Biol Chem; 2007 Nov; 282(48):35337-49. PubMed ID: 17884811
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
    Macháčková K; Mlčochová K; Potalitsyn P; Hanková K; Socha O; Buděšínský M; Muždalo A; Lepšík M; Černeková M; Radosavljević J; Fábry M; Mitrová K; Chrudinová M; Lin J; Yurenko Y; Hobza P; Selicharová I; Žáková L; Jiráček J
    J Biol Chem; 2019 Nov; 294(46):17371-17382. PubMed ID: 31558604
    [TBL] [Abstract][Full Text] [Related]  

  • 29. How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.
    Huang K; Xu B; Hu SQ; Chu YC; Hua QX; Qu Y; Li B; Wang S; Wang RY; Nakagawa SH; Theede AM; Whittaker J; De Meyts P; Katsoyannis PG; Weiss MA
    J Mol Biol; 2004 Aug; 341(2):529-50. PubMed ID: 15276842
    [TBL] [Abstract][Full Text] [Related]  

  • 30. How IGF-1 activates its receptor.
    Kavran JM; McCabe JM; Byrne PO; Connacher MK; Wang Z; Ramek A; Sarabipour S; Shan Y; Shaw DE; Hristova K; Cole PA; Leahy DJ
    Elife; 2014 Sep; 3():. PubMed ID: 25255214
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
    Wan Z; Xu B; Huang K; Chu YC; Li B; Nakagawa SH; Qu Y; Hu SQ; Katsoyannis PG; Weiss MA
    Biochemistry; 2004 Dec; 43(51):16119-33. PubMed ID: 15610006
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
    Menting JG; Gajewiak J; MacRaild CA; Chou DH; Disotuar MM; Smith NA; Miller C; Erchegyi J; Rivier JE; Olivera BM; Forbes BE; Smith BJ; Norton RS; Safavi-Hemami H; Lawrence MC
    Nat Struct Mol Biol; 2016 Oct; 23(10):916-920. PubMed ID: 27617429
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structural consequences of the B5 histidine --> tyrosine mutation in human insulin characterized by X-ray crystallography and conformational analysis.
    Tang L; Whittingham JL; Verma CS; Caves LS; Dodson GG
    Biochemistry; 1999 Sep; 38(37):12041-51. PubMed ID: 10508408
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Diabetes mellitus caused by mutations in human insulin: analysis of impaired receptor binding of insulins Wakayama, Los Angeles and Chicago using pharmacoinformatics.
    Islam MA; Bhayye S; Adeniyi AA; Soliman ME; Pillay TS
    J Biomol Struct Dyn; 2017 Mar; 35(4):724-737. PubMed ID: 26950281
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role of the phenylalanine B25 side chain in directing insulin interaction with its receptor. Steric and conformational effects.
    Nakagawa SH; Tager HS
    J Biol Chem; 1986 Jun; 261(16):7332-41. PubMed ID: 3519607
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor.
    Kristensen C; Andersen AS; Hach M; Wiberg FC; Schäffer L; Kjeldsen T
    Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):981-6. PubMed ID: 7848300
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.
    Gauguin L; Klaproth B; Sajid W; Andersen AS; McNeil KA; Forbes BE; De Meyts P
    J Biol Chem; 2008 Feb; 283(5):2604-13. PubMed ID: 18048361
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Insulin: a small protein with a long journey.
    Hua Q
    Protein Cell; 2010 Jun; 1(6):537-51. PubMed ID: 21204007
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Involvement of phenylalanine 23 in the binding of IGF-1 to the insulin and type I IGF receptor.
    Hodgson DR; May FE; Westley BR
    Regul Pept; 1996 Oct; 66(3):191-6. PubMed ID: 8916274
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Toward the insulin-IGF-I intermediate structures: functional and structural properties of the [TyrB25NMePheB26] insulin mutant.
    Záková L; Brynda J; Au-Alvarez O; Dodson EJ; Dodson GG; Whittingham JL; Brzozowski AM
    Biochemistry; 2004 Dec; 43(51):16293-300. PubMed ID: 15610023
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.