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2. OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease. Festa BP; Berquez M; Gassama A; Amrein I; Ismail HM; Samardzija M; Staiano L; Luciani A; Grimm C; Nussbaum RL; De Matteis MA; Dorchies OM; Scapozza L; Wolfer DP; Devuyst O Hum Mol Genet; 2019 Jun; 28(12):1931-1946. PubMed ID: 30590522 [TBL] [Abstract][Full Text] [Related]
3. Functional Characterization and Rescue of a Deep Intronic Mutation in OCRL Gene Responsible for Lowe Syndrome. Rendu J; Montjean R; Coutton C; Suri M; Chicanne G; Petiot A; Brocard J; Grunwald D; Pietri Rouxel F; Payrastre B; Lunardi J; Dorseuil O; Marty I; Fauré J Hum Mutat; 2017 Feb; 38(2):152-159. PubMed ID: 27790796 [TBL] [Abstract][Full Text] [Related]
4. Genotype Phenotype Correlation in Dent Disease 2 and Review of the Literature: Gianesello L; Arroyo J; Del Prete D; Priante G; Ceol M; Harris PC; Lieske JC; Anglani F Genes (Basel); 2021 Oct; 12(10):. PubMed ID: 34680992 [TBL] [Abstract][Full Text] [Related]
5. Loss of OCRL increases ciliary PI(4,5)P Prosseda PP; Luo N; Wang B; Alvarado JA; Hu Y; Sun Y J Cell Sci; 2017 Oct; 130(20):3447-3454. PubMed ID: 28871046 [TBL] [Abstract][Full Text] [Related]
6. Kidney Tubular Ablation of Inoue K; Balkin DM; Liu L; Nandez R; Wu Y; Tian X; Wang T; Nussbaum R; De Camilli P; Ishibe S J Am Soc Nephrol; 2017 May; 28(5):1399-1407. PubMed ID: 27895154 [TBL] [Abstract][Full Text] [Related]
7. The 5-phosphatase OCRL in Lowe syndrome and Dent disease 2. De Matteis MA; Staiano L; Emma F; Devuyst O Nat Rev Nephrol; 2017 Aug; 13(8):455-470. PubMed ID: 28669993 [TBL] [Abstract][Full Text] [Related]
8. The cellular and physiological functions of the Lowe syndrome protein OCRL1. Mehta ZB; Pietka G; Lowe M Traffic; 2014 May; 15(5):471-87. PubMed ID: 24499450 [TBL] [Abstract][Full Text] [Related]
9. Onset mechanism of a female patient with Dent disease 2. Okamoto T; Sakakibara N; Nozu K; Takahashi T; Hayashi A; Sato Y; Nagano C; Matsuo M; Iijima K; Manabe A Clin Exp Nephrol; 2020 Oct; 24(10):946-954. PubMed ID: 32666344 [TBL] [Abstract][Full Text] [Related]
10. A 3D Renal Proximal Tubule on Chip Model Phenocopies Lowe Syndrome and Dent II Disease Tubulopathy. Naik S; Wood AR; Ongenaert M; Saidiyan P; Elstak ED; Lanz HL; Stallen J; Janssen R; Smythe E; Erdmann KS Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34069732 [TBL] [Abstract][Full Text] [Related]
11. OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome. Luo N; West CC; Murga-Zamalloa CA; Sun L; Anderson RM; Wells CD; Weinreb RN; Travers JB; Khanna H; Sun Y Hum Mol Genet; 2012 Aug; 21(15):3333-44. PubMed ID: 22543976 [TBL] [Abstract][Full Text] [Related]
13. Base editing correction of OCRL in Lowe syndrome: ABE-mediated functional rescue in patient-derived fibroblasts. Chen S; Lo CH; Liu Z; Wang Q; Ning K; Li T; Sun Y Hum Mol Genet; 2024 Jun; 33(13):1142-1151. PubMed ID: 38557732 [TBL] [Abstract][Full Text] [Related]
14. Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy. Bothwell SP; Chan E; Bernardini IM; Kuo YM; Gahl WA; Nussbaum RL J Am Soc Nephrol; 2011 Mar; 22(3):443-8. PubMed ID: 21183592 [TBL] [Abstract][Full Text] [Related]
15. Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells. Barnes J; Salas F; Mokhtari R; Dolstra H; Pedrosa E; Lachman HM Mol Autism; 2018; 9():44. PubMed ID: 30147856 [TBL] [Abstract][Full Text] [Related]
16. Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe. Luo N; Kumar A; Conwell M; Weinreb RN; Anderson R; Sun Y PLoS One; 2013; 8(6):e66727. PubMed ID: 23805271 [TBL] [Abstract][Full Text] [Related]
17. Species-specific difference in expression and splice-site choice in Inpp5b, an inositol polyphosphate 5-phosphatase paralogous to the enzyme deficient in Lowe Syndrome. Bothwell SP; Farber LW; Hoagland A; Nussbaum RL Mamm Genome; 2010 Oct; 21(9-10):458-66. PubMed ID: 20872266 [TBL] [Abstract][Full Text] [Related]
18. The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease. Berquez M; Gadsby JR; Festa BP; Butler R; Jackson SP; Berno V; Luciani A; Devuyst O; Gallop JL Kidney Int; 2020 Oct; 98(4):883-896. PubMed ID: 32919786 [TBL] [Abstract][Full Text] [Related]
19. Suppression of intestinal calcium entry channel TRPV6 by OCRL, a lipid phosphatase associated with Lowe syndrome and Dent disease. Wu G; Zhang W; Na T; Jing H; Wu H; Peng JB Am J Physiol Cell Physiol; 2012 May; 302(10):C1479-91. PubMed ID: 22378746 [TBL] [Abstract][Full Text] [Related]
20. Incomplete cryptic splicing by an intronic mutation of OCRL in patients with partial phenotypes of Lowe syndrome. Nakano E; Yoshida A; Miyama Y; Yabuuchi T; Kajiho Y; Kanda S; Miura K; Oka A; Harita Y J Hum Genet; 2020 Oct; 65(10):831-839. PubMed ID: 32427950 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]