BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 25306876)

  • 1. Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in Toll-like receptor and interferon signaling.
    Ullah MO; Valkov E; Ve T; Williams S; Mas C; Mansell A; Kobe B
    Protein Expr Purif; 2015 Feb; 106():31-40. PubMed ID: 25306876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional interfaces between TICAM-2/TRAM and TICAM-1/TRIF in TLR4 signaling.
    Funami K; Matsumoto M; Oshiumi H; Inagaki F; Seya T
    Biochem Soc Trans; 2017 Aug; 45(4):929-935. PubMed ID: 28630139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactions.
    Stack J; Bowie AG
    J Biol Chem; 2012 Jun; 287(27):22672-82. PubMed ID: 22593572
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRAM is required for TLR2 endosomal signaling to type I IFN induction.
    Stack J; Doyle SL; Connolly DJ; Reinert LS; O'Keeffe KM; McLoughlin RM; Paludan SR; Bowie AG
    J Immunol; 2014 Dec; 193(12):6090-102. PubMed ID: 25385819
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins.
    Ullah MO; Ve T; Mangan M; Alaidarous M; Sweet MJ; Mansell A; Kobe B
    Acta Crystallogr D Biol Crystallogr; 2013 Dec; 69(Pt 12):2420-30. PubMed ID: 24311583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88.
    Ohnishi H; Tochio H; Kato Z; Kawamoto N; Kimura T; Kubota K; Yamamoto T; Funasaka T; Nakano H; Wong RW; Shirakawa M; Kondo N
    PLoS One; 2012; 7(6):e38423. PubMed ID: 22685567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain.
    Piao W; Ru LW; Piepenbrink KH; Sundberg EJ; Vogel SN; Toshchakov VY
    Proc Natl Acad Sci U S A; 2013 Nov; 110(47):19036-41. PubMed ID: 24194546
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule.
    Lysakova-Devine T; Keogh B; Harrington B; Nagpal K; Halle A; Golenbock DT; Monie T; Bowie AG
    J Immunol; 2010 Oct; 185(7):4261-71. PubMed ID: 20802145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a Regulatory Acidic Motif as the Determinant of Membrane Localization of TICAM-2.
    Funami K; Matsumoto M; Enokizono Y; Ishii N; Tatematsu M; Oshiumi H; Inagaki F; Seya T
    J Immunol; 2015 Nov; 195(9):4456-65. PubMed ID: 26408662
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules.
    Matsunaga N; Tsuchimori N; Matsumoto T; Ii M
    Mol Pharmacol; 2011 Jan; 79(1):34-41. PubMed ID: 20881006
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation.
    Klein DC; Skjesol A; Kers-Rebel ED; Sherstova T; Sporsheim B; Egeberg KW; Stokke BT; Espevik T; Husebye H
    Traffic; 2015 Jul; 16(7):677-90. PubMed ID: 25707286
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A genome-wide search of Toll/Interleukin-1 receptor (TIR) domain-containing adapter molecule (TICAM) and their evolutionary divergence from other TIR domain containing proteins.
    Verma S; Sowdhamini R
    Biol Direct; 2022 Sep; 17(1):24. PubMed ID: 36056415
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TICAM-1 and TICAM-2: toll-like receptor adapters that participate in induction of type 1 interferons.
    Seya T; Oshiumi H; Sasai M; Akazawa T; Matsumoto M
    Int J Biochem Cell Biol; 2005 Mar; 37(3):524-9. PubMed ID: 15618008
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.
    Enokizono Y; Kumeta H; Funami K; Horiuchi M; Sarmiento J; Yamashita K; Standley DM; Matsumoto M; Seya T; Inagaki F
    Proc Natl Acad Sci U S A; 2013 Dec; 110(49):19908-13. PubMed ID: 24255114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcriptional regulation of the human TRIF (TIR domain-containing adaptor protein inducing interferon beta) gene.
    Hardy MP; McGGettrick AF; O'Neill LA
    Biochem J; 2004 May; 380(Pt 1):83-93. PubMed ID: 14960149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.
    Bovijn C; Ulrichts P; De Smet AS; Catteeuw D; Beyaert R; Tavernier J; Peelman F
    J Biol Chem; 2012 Feb; 287(6):4088-98. PubMed ID: 22139835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins.
    Núñez Miguel R; Wong J; Westoll JF; Brooks HJ; O'Neill LA; Gay NJ; Bryant CE; Monie TP
    PLoS One; 2007 Aug; 2(8):e788. PubMed ID: 17726518
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.
    Carty M; Goodbody R; Schröder M; Stack J; Moynagh PN; Bowie AG
    Nat Immunol; 2006 Oct; 7(10):1074-81. PubMed ID: 16964262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Integrative modelling of TIR domain-containing adaptor molecule inducing interferon-β (TRIF) provides insights into its autoinhibited state.
    Mahita J; Sowdhamini R
    Biol Direct; 2017 Apr; 12(1):9. PubMed ID: 28427457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.
    Sheedy FJ; O'Neill LA
    J Leukoc Biol; 2007 Aug; 82(2):196-203. PubMed ID: 17449723
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.