These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Ubiquitin chain elongation requires E3-dependent tracking of the emerging conjugate. Kelly A; Wickliffe KE; Song L; Fedrigo I; Rape M Mol Cell; 2014 Oct; 56(2):232-245. PubMed ID: 25306918 [TBL] [Abstract][Full Text] [Related]
4. Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming. Martinez-Chacin RC; Bodrug T; Bolhuis DL; Kedziora KM; Bonacci T; Ordureau A; Gibbs ME; Weissmann F; Qiao R; Grant GD; Cook JG; Peters JM; Wade Harper J; Emanuele MJ; Brown NG Nat Struct Mol Biol; 2020 Jun; 27(6):550-560. PubMed ID: 32393902 [TBL] [Abstract][Full Text] [Related]
5. RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex. Brown NG; VanderLinden R; Watson ER; Qiao R; Grace CR; Yamaguchi M; Weissmann F; Frye JJ; Dube P; Ei Cho S; Actis ML; Rodrigues P; Fujii N; Peters JM; Stark H; Schulman BA Proc Natl Acad Sci U S A; 2015 Apr; 112(17):5272-9. PubMed ID: 25825779 [TBL] [Abstract][Full Text] [Related]
6. Atomic structure of the APC/C and its mechanism of protein ubiquitination. Chang L; Zhang Z; Yang J; McLaughlin SH; Barford D Nature; 2015 Jun; 522(7557):450-454. PubMed ID: 26083744 [TBL] [Abstract][Full Text] [Related]
7. Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Brown NG; VanderLinden R; Watson ER; Weissmann F; Ordureau A; Wu KP; Zhang W; Yu S; Mercredi PY; Harrison JS; Davidson IF; Qiao R; Lu Y; Dube P; Brunner MR; Grace CRR; Miller DJ; Haselbach D; Jarvis MA; Yamaguchi M; Yanishevski D; Petzold G; Sidhu SS; Kuhlman B; Kirschner MW; Harper JW; Peters JM; Stark H; Schulman BA Cell; 2016 Jun; 165(6):1440-1453. PubMed ID: 27259151 [TBL] [Abstract][Full Text] [Related]
8. APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. Tang Z; Li B; Bharadwaj R; Zhu H; Ozkan E; Hakala K; Deisenhofer J; Yu H Mol Biol Cell; 2001 Dec; 12(12):3839-51. PubMed ID: 11739784 [TBL] [Abstract][Full Text] [Related]
9. An E2 accessory domain increases affinity for the anaphase-promoting complex and ensures E2 competition. Girard JR; Tenthorey JL; Morgan DO J Biol Chem; 2015 Oct; 290(40):24614-25. PubMed ID: 26306044 [TBL] [Abstract][Full Text] [Related]
10. Sequential E2s drive polyubiquitin chain assembly on APC targets. Rodrigo-Brenni MC; Morgan DO Cell; 2007 Jul; 130(1):127-39. PubMed ID: 17632060 [TBL] [Abstract][Full Text] [Related]
11. TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Vodermaier HC; Gieffers C; Maurer-Stroh S; Eisenhaber F; Peters JM Curr Biol; 2003 Sep; 13(17):1459-68. PubMed ID: 12956947 [TBL] [Abstract][Full Text] [Related]
13. Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes. Welsh KA; Bolhuis DL; Nederstigt AE; Boyer J; Temple BRS; Bonacci T; Gu L; Ordureau A; Harper JW; Steimel JP; Zhang Q; Emanuele MJ; Harrison JS; Brown NG EMBO J; 2022 Feb; 41(3):e108823. PubMed ID: 34942047 [TBL] [Abstract][Full Text] [Related]
14. The RING-H2-finger protein APC11 as a target of hydrogen peroxide. Chang TS; Jeong W; Lee DY; Cho CS; Rhee SG Free Radic Biol Med; 2004 Aug; 37(4):521-30. PubMed ID: 15256223 [TBL] [Abstract][Full Text] [Related]
15. Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation. Craney A; Kelly A; Jia L; Fedrigo I; Yu H; Rape M Proc Natl Acad Sci U S A; 2016 Feb; 113(6):1540-5. PubMed ID: 26811472 [TBL] [Abstract][Full Text] [Related]
16. The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex. Gmachl M; Gieffers C; Podtelejnikov AV; Mann M; Peters JM Proc Natl Acad Sci U S A; 2000 Aug; 97(16):8973-8. PubMed ID: 10922056 [TBL] [Abstract][Full Text] [Related]
17. UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex. Wu T; Merbl Y; Huo Y; Gallop JL; Tzur A; Kirschner MW Proc Natl Acad Sci U S A; 2010 Jan; 107(4):1355-60. PubMed ID: 20080579 [TBL] [Abstract][Full Text] [Related]
18. Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Bodrug T; Welsh KA; Bolhuis DL; PaulŠ°konis E; Martinez-Chacin RC; Liu B; Pinkin N; Bonacci T; Cui L; Xu P; Roscow O; Amann SJ; Grishkovskaya I; Emanuele MJ; Harrison JS; Steimel JP; Hahn KM; Zhang W; Zhong ED; Haselbach D; Brown NG Nat Struct Mol Biol; 2023 Nov; 30(11):1663-1674. PubMed ID: 37735619 [TBL] [Abstract][Full Text] [Related]
19. Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1. Buschhorn BA; Petzold G; Galova M; Dube P; Kraft C; Herzog F; Stark H; Peters JM Nat Struct Mol Biol; 2011 Jan; 18(1):6-13. PubMed ID: 21186364 [TBL] [Abstract][Full Text] [Related]
20. Cell cycle deregulation by a poxvirus partial mimic of anaphase-promoting complex subunit 11. Mo M; Fleming SB; Mercer AA Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19527-32. PubMed ID: 19887645 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]