These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
24. Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes. van Doorn R; Nijland PG; Dekker N; Witte ME; Lopes-Pinheiro MA; van het Hof B; Kooij G; Reijerkerk A; Dijkstra C; van van der Valk P; van Horssen J; de Vries HE Acta Neuropathol; 2012 Sep; 124(3):397-410. PubMed ID: 22810490 [TBL] [Abstract][Full Text] [Related]
25. Impact of Sphingolipid Mediators on the Determination of Cochlear Survival in Ototoxicity. Tabuchi K; Hara A Curr Mol Pharmacol; 2018; 11(4):279-284. PubMed ID: 29766830 [TBL] [Abstract][Full Text] [Related]
26. Sphingolipids as mediators of inflammation and novel therapeutic target in inflammatory bowel disease. Sukocheva OA; Lukina E; McGowan E; Bishayee A Adv Protein Chem Struct Biol; 2020; 120():123-158. PubMed ID: 32085881 [TBL] [Abstract][Full Text] [Related]
27. Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. Diab KJ; Adamowicz JJ; Kamocki K; Rush NI; Garrison J; Gu Y; Schweitzer KS; Skobeleva A; Rajashekhar G; Hubbard WC; Berdyshev EV; Petrache I Am J Respir Crit Care Med; 2010 Feb; 181(4):344-52. PubMed ID: 19965812 [TBL] [Abstract][Full Text] [Related]
28. Human Remyelination Promoting Antibody Stimulates Astrocytes Proliferation Through Modulation of the Sphingolipid Rheostat in Primary Rat Mixed Glial Cultures. Grassi S; Giussani P; Prioni S; Button D; Cao J; Hakimi I; Sarmiere P; Srinivas M; Cabitta L; Sonnino S; Prinetti A Neurochem Res; 2019 Jun; 44(6):1460-1474. PubMed ID: 30569280 [TBL] [Abstract][Full Text] [Related]
30. Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration. Colombo E; Bassani C; De Angelis A; Ruffini F; Ottoboni L; Comi G; Martino G; Farina C Front Immunol; 2020; 11():635. PubMed ID: 32322257 [TBL] [Abstract][Full Text] [Related]
31. ASP4058, a novel agonist for sphingosine 1-phosphate receptors 1 and 5, ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile. Yamamoto R; Okada Y; Hirose J; Koshika T; Kawato Y; Maeda M; Saito R; Hattori K; Harada H; Nagasaka Y; Morokata T PLoS One; 2014; 9(10):e110819. PubMed ID: 25347187 [TBL] [Abstract][Full Text] [Related]
32. Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate. Demont EH; Andrews BI; Bit RA; Campbell CA; Cooke JW; Deeks N; Desai S; Dowell SJ; Gaskin P; Gray JR; Haynes A; Holmes DS; Kumar U; Morse MA; Osborne GJ; Panchal T; Patel B; Perboni A; Taylor S; Watson R; Witherington J; Willis R ACS Med Chem Lett; 2011 Jun; 2(6):444-9. PubMed ID: 24900328 [TBL] [Abstract][Full Text] [Related]
33. To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. Chew WS; Wang W; Herr DR Pharmacol Res; 2016 Nov; 113(Pt A):521-532. PubMed ID: 27663260 [TBL] [Abstract][Full Text] [Related]
34. Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks. Blankenbach KV; Schwalm S; Pfeilschifter J; Meyer Zu Heringdorf D Front Pharmacol; 2016; 7():167. PubMed ID: 27445808 [TBL] [Abstract][Full Text] [Related]
35. Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. Brait VH; Tarrasón G; Gavaldà A; Godessart N; Planas AM Stroke; 2016 Dec; 47(12):3053-3056. PubMed ID: 27827329 [TBL] [Abstract][Full Text] [Related]
36. Signaling and regulatory functions of bioactive sphingolipids as therapeutic targets in multiple sclerosis. Podbielska M; Krotkiewski H; Hogan EL Neurochem Res; 2012 Jun; 37(6):1154-69. PubMed ID: 22451227 [TBL] [Abstract][Full Text] [Related]
37. An overview of sphingolipid metabolism: from synthesis to breakdown. Gault CR; Obeid LM; Hannun YA Adv Exp Med Biol; 2010; 688():1-23. PubMed ID: 20919643 [TBL] [Abstract][Full Text] [Related]
38. The imbalance in the aortic ceramide/sphingosine-1-phosphate rheostat in ovariectomized rats and the preventive effect of estrogen. Li Y; Zhang W; Li J; Sun Y; Yang Q; Wang S; Luo X; Wang W; Wang K; Bai W; Zhang H; Qin L Lipids Health Dis; 2020 May; 19(1):95. PubMed ID: 32430006 [TBL] [Abstract][Full Text] [Related]
39. Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells. Pyszko J; Strosznajder JB Mol Neurobiol; 2014 Aug; 50(1):38-48. PubMed ID: 24399507 [TBL] [Abstract][Full Text] [Related]
40. Pharmacophore-based design of novel oxadiazoles as selective sphingosine-1-phosphate (S1P) receptor agonists with in vivo efficacy. Quattropani A; Sauer WH; Crosignani S; Dorbais J; Gerber P; Gonzalez J; Marin D; Muzerelle M; Beltran F; Nichols A; Georgi K; Schneider M; Vitte PA; Eligert V; Novo-Perez L; Hantson J; Nock S; Carboni S; de Souza AL; Arrighi JF; Boschert U; Bombrun A ChemMedChem; 2015 Apr; 10(4):688-714. PubMed ID: 25735812 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]