These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 25311193)

  • 1. Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.
    Buck A; Halbritter S; Späth C; Feuchtinger A; Aichler M; Zitzelsberger H; Janssen KP; Walch A
    Anal Bioanal Chem; 2015 Mar; 407(8):2107-16. PubMed ID: 25311193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cross-validation of a mass spectrometric-based method for the therapeutic drug monitoring of irinotecan: implementation of matrix-assisted laser desorption/ionization mass spectrometry in pharmacokinetic measurements.
    Calandra E; Posocco B; Crotti S; Marangon E; Giodini L; Nitti D; Toffoli G; Traldi P; Agostini M
    Anal Bioanal Chem; 2016 Jul; 408(19):5369-77. PubMed ID: 27235158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids.
    Liu X; Flinders C; Mumenthaler SM; Hummon AB
    J Am Soc Mass Spectrom; 2018 Mar; 29(3):516-526. PubMed ID: 29209911
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effective conversion of irinotecan to SN-38 after intratumoral drug delivery to an intracranial murine glioma model in vivo. Laboratory investigation.
    Wang W; Ghandi A; Liebes L; Louie SG; Hofman FM; Schönthal AH; Chen TC
    J Neurosurg; 2011 Mar; 114(3):689-94. PubMed ID: 20415520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MALDI-TOF MS imaging of metabolites with a N-(1-naphthyl) ethylenediamine dihydrochloride matrix and its application to colorectal cancer liver metastasis.
    Wang J; Qiu S; Chen S; Xiong C; Liu H; Wang J; Zhang N; Hou J; He Q; Nie Z
    Anal Chem; 2015 Jan; 87(1):422-30. PubMed ID: 25474421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.
    Nakajima TE; Yanagihara K; Takigahira M; Yasunaga M; Kato K; Hamaguchi T; Yamada Y; Shimada Y; Mihara K; Ochiya T; Matsumura Y
    Cancer Res; 2008 Nov; 68(22):9318-22. PubMed ID: 19010905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors.
    Hattori Y; Shi L; Ding W; Koga K; Kawano K; Hakoshima M; Maitani Y
    J Control Release; 2009 May; 136(1):30-7. PubMed ID: 19331859
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.
    Huber K; Feuchtinger A; Borgmann DM; Li Z; Aichler M; Hauck SM; Zitzelsberger H; Schwaiger M; Keller U; Walch A
    Anal Chem; 2014 Nov; 86(21):10568-75. PubMed ID: 25263480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic activation of irinotecan during intra-arterial chemotherapy of metastatic colorectal cancer.
    Czejka M; Kiss A; Koessner C; Terkola R; Ettlinger D; Schueller J
    Anticancer Res; 2011 Oct; 31(10):3573-8. PubMed ID: 21965780
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion.
    Kalra AV; Kim J; Klinz SG; Paz N; Cain J; Drummond DC; Nielsen UB; Fitzgerald JB
    Cancer Res; 2014 Dec; 74(23):7003-13. PubMed ID: 25273092
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil.
    Nakajima TE; Yasunaga M; Kano Y; Koizumi F; Kato K; Hamaguchi T; Yamada Y; Shirao K; Shimada Y; Matsumura Y
    Int J Cancer; 2008 May; 122(9):2148-53. PubMed ID: 18196580
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models.
    Matsuzaki T; Takagi A; Furuta T; Ueno S; Kurita A; Nohara G; Kodaira H; Sawada S; Hashimoto S
    Oncol Rep; 2012 Jan; 27(1):189-97. PubMed ID: 21935577
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.
    Fioravanti A; Canu B; Alì G; Orlandi P; Allegrini G; Di Desidero T; Emmenegger U; Fontanini G; Danesi R; Del Tacca M; Falcone A; Bocci G
    Eur J Pharmacol; 2009 Oct; 619(1-3):8-14. PubMed ID: 19695243
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An Improved Molecular Histology Method for Ion Suppression Monitoring and Quantification of Phosphatidyl Cholines During MALDI MSI Lipidomics Analyses.
    Jadoul L; Smargiasso N; Pamelard F; Alberts D; Noël A; De Pauw E; Longuespée R
    OMICS; 2016 Feb; 20(2):110-21. PubMed ID: 26871868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug penetration and metabolism in 3D cell cultures treated in a 3D printed fluidic device: assessment of irinotecan via MALDI imaging mass spectrometry.
    LaBonia GJ; Lockwood SY; Heller AA; Spence DM; Hummon AB
    Proteomics; 2016 Jun; 16(11-12):1814-21. PubMed ID: 27198560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.
    Huber K; Aichler M; Sun N; Buck A; Li Z; Fernandez IE; Hauck SM; Zitzelsberger H; Eickelberg O; Janssen KP; Keller U; Walch A
    Histochem Cell Biol; 2014 Oct; 142(4):361-71. PubMed ID: 24824474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cetuximab increases concentrations of irinotecan and of its active metabolite SN-38 in plasma and tumour of human colorectal carcinoma-bearing mice.
    Chu C; Abbara C; Tandia M; Polrot M; Gonin P; Farinotti R; Bonhomme-Faivre L
    Fundam Clin Pharmacol; 2014 Dec; 28(6):652-60. PubMed ID: 24588516
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A spiked tissue-based approach for quantification of phosphatidylcholines in brain section by MALDI mass spectrometry imaging.
    Jadoul L; Longuespée R; Noël A; De Pauw E
    Anal Bioanal Chem; 2015 Mar; 407(8):2095-106. PubMed ID: 25326885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours.
    Tobin P; Clarke S; Seale JP; Lee S; Solomon M; Aulds S; Crawford M; Gallagher J; Eyers T; Rivory L
    Br J Clin Pharmacol; 2006 Jul; 62(1):122-9. PubMed ID: 16842384
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors.
    Koizumi F; Kitagawa M; Negishi T; Onda T; Matsumoto S; Hamaguchi T; Matsumura Y
    Cancer Res; 2006 Oct; 66(20):10048-56. PubMed ID: 17047068
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.