BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 25311616)

  • 1. Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling.
    Alayev A; Doubleday PF; Berger SM; Ballif BA; Holz MK
    J Proteome Res; 2014 Dec; 13(12):5734-42. PubMed ID: 25311616
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells.
    Alayev A; Berger SM; Kramer MY; Schwartz NS; Holz MK
    J Cell Biochem; 2015 Mar; 116(3):450-7. PubMed ID: 25336146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
    J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells.
    Alayev A; Sun Y; Snyder RB; Berger SM; Yu JJ; Holz MK
    Cell Cycle; 2014; 13(3):371-82. PubMed ID: 24304514
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer.
    Taniguchi T; Iizumi Y; Watanabe M; Masuda M; Morita M; Aono Y; Toriyama S; Oishi M; Goi W; Sakai T
    Cell Death Dis; 2016 May; 7(5):e2211. PubMed ID: 27148684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance.
    Ghosh J; Kobayashi M; Ramdas B; Chatterjee A; Ma P; Mali RS; Carlesso N; Liu Y; Plas DR; Chan RJ; Kapur R
    J Clin Invest; 2016 Jul; 126(7):2621-5. PubMed ID: 27294524
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ERK1/2-dependent activation of mTOR/mTORC1/p70S6K regulates thrombin-induced RPE cell proliferation.
    Parrales A; López E; Lee-Rivera I; López-Colomé AM
    Cell Signal; 2013 Apr; 25(4):829-38. PubMed ID: 23291002
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage.
    Cam M; Bid HK; Xiao L; Zambetti GP; Houghton PJ; Cam H
    J Biol Chem; 2014 Feb; 289(7):4083-94. PubMed ID: 24366874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling.
    Rapley J; Oshiro N; Ortiz-Vega S; Avruch J
    J Biol Chem; 2011 Nov; 286(44):38043-38053. PubMed ID: 21914810
    [TBL] [Abstract][Full Text] [Related]  

  • 11. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1.
    Ben-Hur V; Denichenko P; Siegfried Z; Maimon A; Krainer A; Davidson B; Karni R
    Cell Rep; 2013 Jan; 3(1):103-15. PubMed ID: 23273915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway.
    Havel JJ; Li Z; Cheng D; Peng J; Fu H
    Oncogene; 2015 Mar; 34(12):1487-98. PubMed ID: 24704832
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1.
    Völkers M; Toko H; Doroudgar S; Din S; Quijada P; Joyo AY; Ornelas L; Joyo E; Thuerauf DJ; Konstandin MH; Gude N; Glembotski CC; Sussman MA
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12661-6. PubMed ID: 23842089
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation.
    Roca H; Varsos Z; Pienta KJ
    J Biol Chem; 2008 Sep; 283(36):25057-73. PubMed ID: 18611860
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
    Palaniappan M; Menon KM
    Mol Endocrinol; 2010 Sep; 24(9):1782-93. PubMed ID: 20660299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway.
    Palaniappan M; Menon B; Menon KM
    Mol Cell Endocrinol; 2013 Feb; 366(1):81-9. PubMed ID: 23261705
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
    Mi W; Ye Q; Liu S; She QB
    Oncotarget; 2015 Jun; 6(16):13962-77. PubMed ID: 25961827
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer.
    Yang F; Deng R; Qian XJ; Chang SH; Wu XQ; Qin J; Feng GK; Ding K; Zhu XF
    Cell Death Dis; 2014 Mar; 5(3):e1114. PubMed ID: 24625973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
    Wang H; Huang F; Wang J; Wang P; Lv W; Hong L; Li S; Zhou J
    Cell Cycle; 2015; 14(2):232-42. PubMed ID: 25607647
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.