BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 25313067)

  • 1. Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation.
    Shibata S; Arroyo JP; Castañeda-Bueno M; Puthumana J; Zhang J; Uchida S; Stone KL; Lam TT; Lifton RP
    Proc Natl Acad Sci U S A; 2014 Oct; 111(43):15556-61. PubMed ID: 25313067
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potassium depletion stimulates Na-Cl cotransporter
    Ishizawa K; Xu N; Loffing J; Lifton RP; Fujita T; Uchida S; Shibata S
    Biochem Biophys Res Commun; 2016 Nov; 480(4):745-751. PubMed ID: 27942049
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.
    Shibata S; Zhang J; Puthumana J; Stone KL; Lifton RP
    Proc Natl Acad Sci U S A; 2013 May; 110(19):7838-43. PubMed ID: 23576762
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling.
    Ishizawa K; Wang Q; Li J; Yamazaki O; Tamura Y; Fujigaki Y; Uchida S; Lifton RP; Shibata S
    Proc Natl Acad Sci U S A; 2019 Feb; 116(8):3155-3160. PubMed ID: 30718414
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.
    Ohta A; Schumacher FR; Mehellou Y; Johnson C; Knebel A; Macartney TJ; Wood NT; Alessi DR; Kurz T
    Biochem J; 2013 Apr; 451(1):111-22. PubMed ID: 23387299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of KLHL3 and dietary K
    Ostrosky-Frid M; Chávez-Canales M; Zhang J; Andrukhova O; Argaiz ER; Lerdo-de-Tejada F; Murillo-de-Ozores A; Sanchez-Navarro A; Rojas-Vega L; Bobadilla NA; Vazquez N; Castañeda-Bueno M; Alessi DR; Gamba G
    Am J Physiol Renal Physiol; 2021 May; 320(5):F734-F747. PubMed ID: 33682442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
    Susa K; Sohara E; Rai T; Zeniya M; Mori Y; Mori T; Chiga M; Nomura N; Nishida H; Takahashi D; Isobe K; Inoue Y; Takeishi K; Takeda N; Sasaki S; Uchida S
    Hum Mol Genet; 2014 Oct; 23(19):5052-60. PubMed ID: 24821705
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation.
    Wu G; Peng JB
    FEBS Lett; 2013 Jun; 587(12):1717-22. PubMed ID: 23665031
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice.
    Ishizawa K; Wang Q; Li J; Xu N; Nemoto Y; Morimoto C; Fujii W; Tamura Y; Fujigaki Y; Tsukamoto K; Fujita T; Uchida S; Shibata S
    J Am Soc Nephrol; 2019 May; 30(5):782-794. PubMed ID: 30914436
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
    Maeoka Y; Ferdaus MZ; Cornelius RJ; Sharma A; Su XT; Miller LN; Robertson JA; Gurley SB; Yang CL; Ellison DH; McCormick JA
    J Am Soc Nephrol; 2022 Mar; 33(3):584-600. PubMed ID: 35064051
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kelch-like 3/Cullin 3 ubiquitin ligase complex and WNK signaling in salt-sensitive hypertension and electrolyte disorder.
    Sohara E; Uchida S
    Nephrol Dial Transplant; 2016 Sep; 31(9):1417-24. PubMed ID: 26152401
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.
    Yoshizaki Y; Mori Y; Tsuzaki Y; Mori T; Nomura N; Wakabayashi M; Takahashi D; Zeniya M; Kikuchi E; Araki Y; Ando F; Isobe K; Nishida H; Ohta A; Susa K; Inoue Y; Chiga M; Rai T; Sasaki S; Uchida S; Sohara E
    Biochem Biophys Res Commun; 2015 Nov; 467(2):229-34. PubMed ID: 26435498
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decreased KLHL3 expression is involved in the activation of WNK-OSR1/SPAK-NCC cascade in type 1 diabetic mice.
    Guo Q; Zhang Y; Jiang GR; Zhang C
    Pflugers Arch; 2021 Feb; 473(2):185-196. PubMed ID: 33432425
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a novel KLHL3-interacting motif in the C-terminal region of WNK4.
    Wang L; Wu G; Peng JB
    Biochem Biophys Res Commun; 2023 Aug; 670():87-93. PubMed ID: 37285722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of KLHL3 at serine 433 impairs its interaction with the acidic motif of WNK4: a molecular dynamics study.
    Wang L; Peng JB
    Protein Sci; 2017 Feb; 26(2):163-173. PubMed ID: 27727489
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
    Susa K; Sohara E; Takahashi D; Okado T; Rai T; Uchida S
    Biochem Biophys Res Commun; 2017 Sep; 491(3):727-732. PubMed ID: 28743496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generation and analysis of a mouse model of pseudohypoaldosteronism type II caused by KLHL3 mutation in BTB domain.
    Lin CM; Cheng CJ; Yang SS; Tseng MH; Yen MT; Sung CC; Lin SH
    FASEB J; 2019 Jan; 33(1):1051-1061. PubMed ID: 30148674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.
    Cornelius RJ; Zhang C; Erspamer KJ; Agbor LN; Sigmund CD; Singer JD; Yang CL; Ellison DH
    Am J Physiol Renal Physiol; 2018 Oct; 315(4):F1006-F1018. PubMed ID: 29897280
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.
    Schumacher FR; Sorrell FJ; Alessi DR; Bullock AN; Kurz T
    Biochem J; 2014 Jun; 460(2):237-46. PubMed ID: 24641320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4.
    Castañeda-Bueno M; Arroyo JP; Zhang J; Puthumana J; Yarborough O; Shibata S; Rojas-Vega L; Gamba G; Rinehart J; Lifton RP
    Proc Natl Acad Sci U S A; 2017 Jan; 114(5):E879-E886. PubMed ID: 28096417
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.