BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 25315710)

  • 1. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients.
    Bandino A; Geerts D; Koster J; Bachmann AS
    Cell Oncol (Dordr); 2014 Dec; 37(6):387-98. PubMed ID: 25315710
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
    Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of inhibitors of deoxyhypusine synthase on the differentiation of mouse neuroblastoma and erythroleukemia cells.
    Chen ZP; Yan YP; Ding QJ; Knapp S; Potenza JA; Schugar HJ; Chen KY
    Cancer Lett; 1996 Aug; 105(2):233-9. PubMed ID: 8697449
    [TBL] [Abstract][Full Text] [Related]  

  • 4. eIF5A-Independent Role of DHPS in p21
    Becker AE; Wu PK; Park JI
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34947982
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aminohexanoic hydroxamate is a potent inducer of the differentiation of mouse neuroblastoma cells.
    Lu J; Chen ZP; Yan YP; Knapp S; Schugar H; Chen KY
    Cancer Lett; 2000 Nov; 160(1):59-66. PubMed ID: 11098085
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
    Coni S; Serrao SM; Yurtsever ZN; Di Magno L; Bordone R; Bertani C; Licursi V; Ianniello Z; Infante P; Moretti M; Petroni M; Guerrieri F; Fatica A; Macone A; De Smaele E; Di Marcotullio L; Giannini G; Maroder M; Agostinelli E; Canettieri G
    Cell Death Dis; 2020 Dec; 11(12):1045. PubMed ID: 33303756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target.
    Yco LP; Geerts D; Mocz G; Koster J; Bachmann AS
    BMC Cancer; 2015 Jun; 15():477. PubMed ID: 26093909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture.
    Shi XP; Yin KC; Ahern J; Davis LJ; Stern AM; Waxman L
    Biochim Biophys Acta; 1996 Jan; 1310(1):119-26. PubMed ID: 9244184
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Independent roles of eIF5A and polyamines in cell proliferation.
    Nishimura K; Murozumi K; Shirahata A; Park MH; Kashiwagi K; Igarashi K
    Biochem J; 2005 Feb; 385(Pt 3):779-85. PubMed ID: 15377278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
    Preukschas M; Hagel C; Schulte A; Weber K; Lamszus K; Sievert H; Pällmann N; Bokemeyer C; Hauber J; Braig M; Balabanov S
    PLoS One; 2012; 7(8):e43468. PubMed ID: 22927971
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N(1)-guanyl-1,7,-diamineoheptane, an inhibitor of deoxyhypusine synthase, suppresses differentiation and induces apoptosis via mitochondrial and AMPK pathways in immortalized and malignant human oral keratinocytes.
    Lee SK; Lee J; Lee SI; Bae WJ; Lee YM; Park JS; Lee SK; Park SJ; Min SK; Kim EC
    J Oral Pathol Med; 2009 Nov; 38(10):792-800. PubMed ID: 19656269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells.
    Wallick CJ; Gamper I; Thorne M; Feith DJ; Takasaki KY; Wilson SM; Seki JA; Pegg AE; Byus CV; Bachmann AS
    Oncogene; 2005 Aug; 24(36):5606-18. PubMed ID: 16007177
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes.
    Colvin SC; Maier B; Morris DL; Tersey SA; Mirmira RG
    J Biol Chem; 2013 Dec; 288(51):36226-35. PubMed ID: 24196968
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
    Tanaka Y; Kurasawa O; Yokota A; Klein MG; Ono K; Saito B; Matsumoto S; Okaniwa M; Ambrus-Aikelin G; Morishita D; Kitazawa S; Uchiyama N; Ogawa K; Kimura H; Imamura S
    J Med Chem; 2020 Mar; 63(6):3215-3226. PubMed ID: 32142284
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy.
    Bourourou M; Gouix E; Melis N; Friard J; Heurteaux C; Tauc M; Blondeau N
    J Cereb Blood Flow Metab; 2021 May; 41(5):1080-1090. PubMed ID: 32615885
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis.
    Lee Y; Kim HK; Park HE; Park MH; Joe YA
    Mol Cell Biochem; 2002 Aug; 237(1-2):69-76. PubMed ID: 12236588
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder.
    Ganapathi M; Padgett LR; Yamada K; Devinsky O; Willaert R; Person R; Au PB; Tagoe J; McDonald M; Karlowicz D; Wolf B; Lee J; Shen Y; Okur V; Deng L; LeDuc CA; Wang J; Hanner A; Mirmira RG; Park MH; Mastracci TL; Chung WK
    Am J Hum Genet; 2019 Feb; 104(2):287-298. PubMed ID: 30661771
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor.
    Lee YB; Joe YA; Wolff EC; Dimitriadis EK; Park MH
    Biochem J; 1999 May; 340 ( Pt 1)(Pt 1):273-81. PubMed ID: 10229683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.
    Samal K; Zhao P; Kendzicky A; Yco LP; McClung H; Gerner E; Burns M; Bachmann AS; Sholler G
    Int J Cancer; 2013 Sep; 133(6):1323-33. PubMed ID: 23457004
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.
    Nakanishi S; Cleveland JL
    Amino Acids; 2016 Oct; 48(10):2353-62. PubMed ID: 27357307
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.