136 related articles for article (PubMed ID: 25316768)
1. In vitro antitumor mechanism of (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)methanesulfonamide.
Lu T; Laughton CA; Wang S; Bradshaw TD
Mol Pharmacol; 2015 Jan; 87(1):18-30. PubMed ID: 25316768
[TBL] [Abstract][Full Text] [Related]
2. Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities.
Lu T; Goh AW; Yu M; Adams J; Lam F; Teo T; Li P; Noll B; Zhong L; Diab S; Chahrour O; Hu A; Abbas AY; Liu X; Huang S; Sumby CJ; Milne R; Midgley C; Wang S
J Med Chem; 2014 Mar; 57(6):2275-91. PubMed ID: 24471873
[TBL] [Abstract][Full Text] [Related]
3. Rigosertib induces cell death of a myelodysplastic syndrome-derived cell line by DNA damage-induced G2/M arrest.
Hyoda T; Tsujioka T; Nakahara T; Suemori S; Okamoto S; Kataoka M; Tohyama K
Cancer Sci; 2015 Mar; 106(3):287-93. PubMed ID: 25580850
[TBL] [Abstract][Full Text] [Related]
4. Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
Lu PH; Kung FL; Kuo SC; Chueh SC; Guh JH
Naunyn Schmiedebergs Arch Pharmacol; 2006 Dec; 374(3):223-33. PubMed ID: 17102938
[TBL] [Abstract][Full Text] [Related]
5. A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
Liou JP; Hsu KS; Kuo CC; Chang CY; Chang JY
J Pharmacol Exp Ther; 2007 Oct; 323(1):398-405. PubMed ID: 17660383
[TBL] [Abstract][Full Text] [Related]
6. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
[TBL] [Abstract][Full Text] [Related]
7. Styryl sulfonyl compounds inhibit translation of cyclin D1 in mantle cell lymphoma cells.
Prasad A; Park IW; Allen H; Zhang X; Reddy MV; Boominathan R; Reddy EP; Groopman JE
Oncogene; 2009 Mar; 28(12):1518-28. PubMed ID: 19198627
[TBL] [Abstract][Full Text] [Related]
8. Effect of ON 01910.Na, an anticancer mitotic inhibitor, on cell-cycle progression correlates with RanGAP1 hyperphosphorylation.
Oussenko IA; Holland JF; Reddy EP; Ohnuma T
Cancer Res; 2011 Jul; 71(14):4968-76. PubMed ID: 21646468
[TBL] [Abstract][Full Text] [Related]
9. 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.
Chang WL; Chang CS; Chiang PC; Ho YF; Liu JF; Chang KW; Guh JH
Br J Pharmacol; 2010 Aug; 160(7):1677-89. PubMed ID: 20649571
[TBL] [Abstract][Full Text] [Related]
10. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell.
Hasanpourghadi M; Karthikeyan C; Pandurangan AK; Looi CY; Trivedi P; Kobayashi K; Tanaka K; Wong WF; Mustafa MR
J Exp Clin Cancer Res; 2016 Mar; 35():58. PubMed ID: 27030360
[TBL] [Abstract][Full Text] [Related]
11. Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-{2-methoxy-5-[(2',4',6'-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): synthesis, structure-activity relationship, and biological activity.
Reddy MV; Venkatapuram P; Mallireddigari MR; Pallela VR; Cosenza SC; Robell KA; Akula B; Hoffman BS; Reddy EP
J Med Chem; 2011 Sep; 54(18):6254-76. PubMed ID: 21812421
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of novel cell cycle inhibitors in mantle cell lymphoma.
Park IW; Reddy MV; Reddy EP; Groopman JE
Oncogene; 2007 Aug; 26(38):5635-42. PubMed ID: 17369860
[TBL] [Abstract][Full Text] [Related]
13. Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells.
Lee ST; Lee JY; Han CR; Kim YH; Jun do Y; Taub D; Kim YH
Biochem Pharmacol; 2015 Apr; 94(4):257-69. PubMed ID: 25732194
[TBL] [Abstract][Full Text] [Related]
14. LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells.
Zhao L; Miao HC; Li WJ; Sun Y; Huang SL; Li ZY; Guo QL
Mol Carcinog; 2016 May; 55(5):778-92. PubMed ID: 25945460
[TBL] [Abstract][Full Text] [Related]
15. Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na.
Mäki-Jouppila JH; Laine LJ; Rehnberg J; Narvi E; Tiikkainen P; Hukasova E; Halonen P; Lindqvist A; Kallio L; Poso A; Kallio MJ
Mol Cancer Ther; 2014 May; 13(5):1054-66. PubMed ID: 24748653
[TBL] [Abstract][Full Text] [Related]
16. A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent.
Baker SJ; Cosenza SC; Athuluri-Divakar S; Reddy MVR; Vasquez-Del Carpio R; Jain R; Aggarwal AK; Reddy EP
Mol Cell; 2020 Jul; 79(1):180-190.e4. PubMed ID: 32619468
[TBL] [Abstract][Full Text] [Related]
17. SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
Zhao P; Chen L; Li LH; Wei ZF; Tong B; Jia YG; Kong LY; Xia YF; Dai Y
BMC Cancer; 2014 Dec; 14():987. PubMed ID: 25527123
[TBL] [Abstract][Full Text] [Related]
18. 3'-hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction.
Tsai CH; Hung AC; Chen YY; Chiu YW; Hsieh PW; Lee YC; Su YH; Chang PC; Hu SC; Yuan SF
Oncotarget; 2017 Mar; 8(11):18106-18117. PubMed ID: 28178649
[TBL] [Abstract][Full Text] [Related]
19. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
[TBL] [Abstract][Full Text] [Related]
20. Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerization.
Mahale S; Bharate SB; Manda S; Joshi P; Jenkins PR; Vishwakarma RA; Chaudhuri B
Cell Death Dis; 2015 May; 6(5):e1743. PubMed ID: 25950473
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
