BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 25319061)

  • 1. Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial.
    Élez E; Kocáková I; Höhler T; Martens UM; Bokemeyer C; Van Cutsem E; Melichar B; Smakal M; Csőszi T; Topuzov E; Orlova R; Tjulandin S; Rivera F; Straub J; Bruns R; Quaratino S; Tabernero J
    Ann Oncol; 2015 Jan; 26(1):132-140. PubMed ID: 25319061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. No survival benefit from adding cetuximab or panitumumab to oxaliplatin-based chemotherapy in the first-line treatment of metastatic colorectal cancer in KRAS wild type patients: a meta-analysis.
    Zhou SW; Huang YY; Wei Y; Jiang ZM; Zhang YD; Yang Q; Xie DR
    PLoS One; 2012; 7(11):e50925. PubMed ID: 23226426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy.
    Eng C; Bessudo A; Hart LL; Severtsev A; Gladkov O; Müller L; Kopp MV; Vladimirov V; Langdon R; Kotiv B; Barni S; Hsu C; Bolotin E; von Roemeling R; Schwartz B; Bendell JC
    Int J Cancer; 2016 Jul; 139(1):177-86. PubMed ID: 26891420
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial.
    Wang DS; Ren C; Li SS; Fong WP; Wu XJ; Xiao J; Li BK; Zheng Y; Ding PR; Chen G; Qiu MZ; Wang ZQ; Wang FH; Luo HY; Wang F; Wang XZ; Wang LY; Xie DJ; Chen T; Li LR; Lu ZH; Zhai XH; Liu TS; Yuan Y; Chen JQ; Tan Q; Pan ZZ; Wan DS; Zhang R; Yuan YF; Xu RH; Li YH
    PLoS Med; 2024 May; 21(5):e1004389. PubMed ID: 38728364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Immunoglobulin G fragment C receptor polymorphisms and KRAS mutations: are they useful biomarkers of clinical outcome in advanced colorectal cancer treated with anti-EGFR-based therapy?
    Paez D; Paré L; Espinosa I; Salazar J; del Rio E; Barnadas A; Marcuello E; Baiget M
    Cancer Sci; 2010 Sep; 101(9):2048-53. PubMed ID: 20550522
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08.
    Masuishi T; Tsuji A; Kotaka M; Nakamura M; Kochi M; Takagane A; Shimada K; Denda T; Segawa Y; Tanioka H; Hara H; Sagawa T; Watanabe T; Takahashi T; Negoro Y; Manaka D; Fujita H; Suto T; Takeuchi M; Ichikawa W; Fujii M
    Br J Cancer; 2020 Nov; 123(10):1490-1495. PubMed ID: 32863385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.
    Moretto R; Cremolini C; Rossini D; Pietrantonio F; Battaglin F; Mennitto A; Bergamo F; Loupakis F; Marmorino F; Berenato R; Marsico VA; Caporale M; Antoniotti C; Masi G; Salvatore L; Borelli B; Fontanini G; Lonardi S; De Braud F; Falcone A
    Oncologist; 2016 Aug; 21(8):988-94. PubMed ID: 27382031
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The evolving role of monoclonal antibodies in colorectal cancer: early presumptions and impact on clinical trial development.
    Eng C
    Oncologist; 2010; 15(1):73-84. PubMed ID: 20067946
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fluorouracil, Leucovorin, and Irinotecan Plus Cetuximab Versus Cetuximab as Maintenance Therapy in First-Line Therapy for
    Pinto C; Orlandi A; Normanno N; Maiello E; Calegari MA; Antonuzzo L; Bordonaro R; Zampino MG; Pini S; Bergamo F; Tonini G; Avallone A; Latiano TP; Rosati G; Cogoni AA; Ballestrero A; Zaniboni A; Roselli M; Tamberi S; Barone C
    J Clin Oncol; 2024 Apr; 42(11):1278-1287. PubMed ID: 38181312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of Combined Immune Checkpoint Inhibition vs Best Supportive Care Alone in Patients With Advanced Colorectal Cancer: The Canadian Cancer Trials Group CO.26 Study.
    Chen EX; Jonker DJ; Loree JM; Kennecke HF; Berry SR; Couture F; Ahmad CE; Goffin JR; Kavan P; Harb M; Colwell B; Samimi S; Samson B; Abbas T; Aucoin N; Aubin F; Koski SL; Wei AC; Magoski NM; Tu D; O'Callaghan CJ
    JAMA Oncol; 2020 Jun; 6(6):831-838. PubMed ID: 32379280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modified FOLFOX6 plus bevacizumab with and without nivolumab for first-line treatment of metastatic colorectal cancer: phase 2 results from the CheckMate 9X8 randomized clinical trial.
    Lenz HJ; Parikh A; Spigel DR; Cohn AL; Yoshino T; Kochenderfer M; Elez E; Shao SH; Deming D; Holdridge R; Larson T; Chen E; Mahipal A; Ucar A; Cullen D; Baskin-Bey E; Kang T; Hammell AB; Yao J; Tabernero J
    J Immunother Cancer; 2024 Mar; 12(3):. PubMed ID: 38485190
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated
    Fakih MG; Salvatore L; Esaki T; Modest DP; Lopez-Bravo DP; Taieb J; Karamouzis MV; Ruiz-Garcia E; Kim TW; Kuboki Y; Meriggi F; Cunningham D; Yeh KH; Chan E; Chao J; Saportas Y; Tran Q; Cremolini C; Pietrantonio F
    N Engl J Med; 2023 Dec; 389(23):2125-2139. PubMed ID: 37870968
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genome-wide DNA methylation status is a predictor of the efficacy of anti-EGFR antibodies in the second-line treatment of metastatic colorectal cancer: Translational research of the EPIC trial.
    Ouchi K; Takahashi S; Sasaki K; Yoshida Y; Taniguchi S; Kasahara Y; Komine K; Imai H; Saijo K; Shirota H; Takahashi M; Ishioka C
    Int J Colorectal Dis; 2024 Jun; 39(1):89. PubMed ID: 38862615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phase 1 pharmacokinetic study of MK-0646 (dalotuzumab), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in combination with cetuximab and irinotecan in Japanese patients with advanced colorectal cancer.
    Doi T; Muro K; Yoshino T; Fuse N; Ura T; Takahari D; Feng HP; Shimamoto T; Noguchi K; Ohtsu A
    Cancer Chemother Pharmacol; 2013 Sep; 72(3):643-52. PubMed ID: 23921573
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Observational study on quality of life, safety, and effectiveness of first-line cetuximab plus chemotherapy in KRAS wild-type metastatic colorectal cancer patients: the ObservEr Study.
    Pinto C; Di Fabio F; Rosati G; Lolli IR; Ruggeri EM; Ciuffreda L; Ferrari D; Lo Re G; Rosti G; Tralongo P; Ferrara R; Alabiso O; Chiara S; Ianniello GP; Frassoldati A; Bilancia D; Campanella GA; Signorelli C; Racca P; Benincasa E; Stroppolo ME; Di Costanzo F
    Cancer Med; 2016 Nov; 5(11):3272-3281. PubMed ID: 27748041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ramucirumab plus FOLFIRI as second-line treatment for patients with RAS wild-type metastatic colorectal cancer previously treated with anti-EGFR antibody: JACCRO CC-16.
    Yasui H; Okita Y; Nakamura M; Sagawa T; Watanabe T; Kataoka K; Manaka D; Shiraishi K; Akazawa N; Okuno T; Shimura T; Shiozawa M; Sunakawa Y; Ota H; Kotaka M; Okuyama H; Takeuchi M; Ichikawa W; Fujii M; Tsuji A
    ESMO Open; 2023 Oct; 8(5):101636. PubMed ID: 37703596
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A prospective Phase II study to examine the relationship between quality of life and adverse events of first-line chemotherapy plus cetuximab in patients with KRAS wild-type unresectable metastatic colorectal cancer: QUACK trial.
    Iwamoto S; Ooki A; Morita S; Hara H; Tanioka H; Satake H; Kataoka M; Kotaka M; Kagawa Y; Nakamura M; Shingai T; Ishikawa M; Miyake Y; Sudo T; Hashiguchi Y; Yabuno T; Sakamoto J; Tsuji A; Ando M; Yamaguchi K
    Cancer Med; 2018 Sep; 7(9):4217-4227. PubMed ID: 30051609
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol.
    Ottaiano A; Scala S; Normanno N; Napolitano M; Capozzi M; Rachiglio AM; Roma C; Trotta AM; D'Alterio C; Portella L; Romano C; Cassata A; Casaretti R; Silvestro L; Nappi A; Tafuto S; Avallone A; De Stefano A; Tamburini M; Picone C; Petrillo A; Izzo F; Palaia R; Albino V; Amore A; Belli A; Pace U; Di Marzo M; Chiodini P; Botti G; De Feo G; Delrio P; Nasti G
    BMC Cancer; 2019 Sep; 19(1):899. PubMed ID: 31500586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ANCHOR CRC: Results From a Single-Arm, Phase II Study of Encorafenib Plus Binimetinib and Cetuximab in Previously Untreated
    Van Cutsem E; Taieb J; Yaeger R; Yoshino T; Grothey A; Maiello E; Elez E; Dekervel J; Ross P; Ruiz-Casado A; Graham J; Kato T; Ruffinelli JC; André T; Carrière Roussel E; Klauck I; Groc M; Vedovato JC; Tabernero J
    J Clin Oncol; 2023 May; 41(14):2628-2637. PubMed ID: 36763936
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.
    Dotan E; Cohen SJ; Starodub AN; Lieu CH; Messersmith WA; Simpson PS; Guarino MJ; Marshall JL; Goldberg RM; Hecht JR; Wegener WA; Sharkey RM; Govindan SV; Goldenberg DM; Berlin JD
    J Clin Oncol; 2017 Oct; 35(29):3338-3346. PubMed ID: 28817371
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.