BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 25319697)

  • 1. The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function.
    Hou H; Chávez AE; Wang CC; Yang H; Gu H; Siddoway BA; Hall BJ; Castillo PE; Xia H
    J Neurosci; 2014 Oct; 34(42):14006-12. PubMed ID: 25319697
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NSC23766, a widely used inhibitor of Rac1 activation, additionally acts as a competitive antagonist at muscarinic acetylcholine receptors.
    Levay M; Krobert KA; Wittig K; Voigt N; Bermudez M; Wolber G; Dobrev D; Levy FO; Wieland T
    J Pharmacol Exp Ther; 2013 Oct; 347(1):69-79. PubMed ID: 23887096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133.
    Lee B; Butcher GQ; Hoyt KR; Impey S; Obrietan K
    J Neurosci; 2005 Feb; 25(5):1137-48. PubMed ID: 15689550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets.
    Dütting S; Heidenreich J; Cherpokova D; Amin E; Zhang SC; Ahmadian MR; Brakebusch C; Nieswandt B
    J Thromb Haemost; 2015 May; 13(5):827-38. PubMed ID: 25628054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Magnesium Acts as a Second Messenger in the Regulation of NMDA Receptor-Mediated CREB Signaling in Neurons.
    Hou H; Wang L; Fu T; Papasergi M; Yule DI; Xia H
    Mol Neurobiol; 2020 Jun; 57(6):2539-2550. PubMed ID: 32215817
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blockade of NMDA Receptors and Nitric Oxide Synthesis Potentiated Morphine-Induced Anti-Allodynia via Attenuating Pain-Related Amygdala pCREB/CREB Signaling Pathway.
    Tolou-Dabbaghian B; Delphi L; Rezayof A
    J Pain; 2019 Aug; 20(8):885-897. PubMed ID: 30707953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of glycine site and GluN2B subunit of NMDA receptors is necessary for ERK/CREB signaling cascade in rostral anterior cingulate cortex in rats: implications for affective pain.
    Cao H; Ren WH; Zhu MY; Zhao ZQ; Zhang YQ
    Neurosci Bull; 2012 Feb; 28(1):77-87. PubMed ID: 22233892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4.
    Mills SC; Howell L; Beekman A; Stokes L; Mueller A
    Cell Signal; 2018 Jan; 42():88-96. PubMed ID: 29050986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model.
    Veluthakal R; Sidarala V; Kowluru A
    Cell Physiol Biochem; 2016; 39(2):760-7. PubMed ID: 27467102
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interactions between ionotropic and metabotropic glutamate receptors regulate cAMP response element-binding protein phosphorylation in cultured striatal neurons.
    Mao L; Wang JQ
    Neuroscience; 2002; 115(2):395-402. PubMed ID: 12421605
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Rac1 activity by NSC23766 prevents cartilage endplate degeneration via Wnt/β-catenin pathway.
    Jiang C; Sun ZM; Zhu DC; Guo Q; Xu JJ; Lin JH; Chen ZX; Wu YS
    J Cell Mol Med; 2020 Mar; 24(6):3582-3592. PubMed ID: 32040269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of Rac1 signalling pathway in the development and maintenance of acute inflammatory pain induced by bee venom injection.
    Wang Y; Lu YF; Li CL; Sun W; Li Z; Wang RR; He T; Yang F; Yang Y; Wang XL; Guan SM; Chen J
    Br J Pharmacol; 2016 Mar; 173(5):937-50. PubMed ID: 26700000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NMDA and D1 receptors regulate the phosphorylation of CREB and the induction of c-fos in striatal neurons in primary culture.
    Das S; Grunert M; Williams L; Vincent SR
    Synapse; 1997 Mar; 25(3):227-33. PubMed ID: 9068120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor stimulation in rats.
    Haberny SL; Carr KD
    Neuroscience; 2005; 132(4):1035-43. PubMed ID: 15857708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.
    Wang PL; Niidome T; Akaike A; Kihara T; Sugimoto H
    J Neurosci Res; 2009 Jul; 87(9):2105-14. PubMed ID: 19267423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway.
    Valera E; Sánchez-Martín FJ; Ferrer-Montiel AV; Messeguer A; Merino JM
    Neurochem Int; 2008 Nov; 53(5):148-54. PubMed ID: 18694792
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Developmentally regulated NMDA receptor-dependent dephosphorylation of cAMP response element-binding protein (CREB) in hippocampal neurons.
    Sala C; Rudolph-Correia S; Sheng M
    J Neurosci; 2000 May; 20(10):3529-36. PubMed ID: 10804193
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na+ channel.
    Karpushev AV; Levchenko V; Ilatovskaya DV; Pavlov TS; Staruschenko A
    Hypertension; 2011 May; 57(5):996-1002. PubMed ID: 21464391
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rac1 silencing, NSC23766 and EHT1864 reduce growth and actin organization of bladder smooth muscle cells.
    Wang R; Yu Q; Wang X; Li B; Ciotkowska A; Rutz B; Wang Y; Stief CG; Hennenberg M
    Life Sci; 2020 Nov; 261():118468. PubMed ID: 32961232
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase signaling cascades.
    Stankiewicz TR; Ramaswami SA; Bouchard RJ; Aktories K; Linseman DA
    J Biol Chem; 2015 Apr; 290(15):9363-76. PubMed ID: 25666619
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.