These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 25326420)

  • 1. IKKβ is an IRF5 kinase that instigates inflammation.
    Ren J; Chen X; Chen ZJ
    Proc Natl Acad Sci U S A; 2014 Dec; 111(49):17438-43. PubMed ID: 25326420
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRAK4 kinase activity controls Toll-like receptor-induced inflammation through the transcription factor IRF5 in primary human monocytes.
    Cushing L; Winkler A; Jelinsky SA; Lee K; Korver W; Hawtin R; Rao VR; Fleming M; Lin LL
    J Biol Chem; 2017 Nov; 292(45):18689-18698. PubMed ID: 28924041
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.
    Lopez-Pelaez M; Lamont DJ; Peggie M; Shpiro N; Gray NS; Cohen P
    Proc Natl Acad Sci U S A; 2014 Dec; 111(49):17432-7. PubMed ID: 25326418
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming.
    Hoepel W; Newling M; Vogelpoel LTC; Sritharan L; Hansen IS; Kapsenberg ML; Baeten DLP; Everts B; den Dunnen J
    Front Immunol; 2019; 10():739. PubMed ID: 31024565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation.
    Carter RS; Pennington KN; Arrate P; Oltz EM; Ballard DW
    J Biol Chem; 2005 Dec; 280(52):43272-9. PubMed ID: 16267042
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway.
    Bergstrøm B; Aune MH; Awuh JA; Kojen JF; Blix KJ; Ryan L; Flo TH; Mollnes TE; Espevik T; Stenvik J
    J Immunol; 2015 Aug; 195(3):1100-11. PubMed ID: 26085680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
    Ryzhakov G; Almuttaqi H; Corbin AL; Berthold DL; Khoyratty T; Eames HL; Bullers S; Pearson C; Ai Z; Zec K; Bonham S; Fischer R; Jostins-Dean L; Travis SPL; Kessler BM; Udalova IA
    Nat Commun; 2021 Nov; 12(1):6702. PubMed ID: 34795257
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.
    Palkowitsch L; Leidner J; Ghosh S; Marienfeld RB
    J Biol Chem; 2008 Jan; 283(1):76-86. PubMed ID: 17977820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of interferon regulatory factor 5 by site specific phosphorylation.
    Chang Foreman HC; Van Scoy S; Cheng TF; Reich NC
    PLoS One; 2012; 7(3):e33098. PubMed ID: 22412986
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.
    Ban T; Sato GR; Nishiyama A; Akiyama A; Takasuna M; Umehara M; Suzuki S; Ichino M; Matsunaga S; Kimura A; Kimura Y; Yanai H; Miyashita S; Kuromitsu J; Tsukahara K; Yoshimatsu K; Endo I; Yamamoto T; Hirano H; Ryo A; Taniguchi T; Tamura T
    Immunity; 2016 Aug; 45(2):319-32. PubMed ID: 27521268
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1.
    Higashimoto T; Chan N; Lee YK; Zandi E
    J Biol Chem; 2008 Dec; 283(51):35354-67. PubMed ID: 18957422
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microbial recognition by GEF-H1 controls IKKε mediated activation of IRF5.
    Zhao Y; Zagani R; Park SM; Yoshida N; Shah P; Reinecker HC
    Nat Commun; 2019 Mar; 10(1):1349. PubMed ID: 30902986
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription.
    Buss H; Dörrie A; Schmitz ML; Hoffmann E; Resch K; Kracht M
    J Biol Chem; 2004 Dec; 279(53):55633-43. PubMed ID: 15489227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes.
    Yang C; Bachu M; Du Y; Brauner C; Yuan R; Ah Kioon MD; Chesi G; Barrat FJ; Ivashkiv LB
    Nat Commun; 2022 Jun; 13(1):3426. PubMed ID: 35701499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling.
    Abe H; Satoh J; Shirasaka Y; Kogure A; Kato H; Ito S; Fujita T
    Mol Cell Biol; 2020 Feb; 40(5):. PubMed ID: 31818880
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected].
    Tang ED; Inohara N; Wang CY; Nuñez G; Guan KL
    J Biol Chem; 2003 Oct; 278(40):38566-70. PubMed ID: 12890679
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
    Kray AE; Carter RS; Pennington KN; Gomez RJ; Sanders LE; Llanes JM; Khan WN; Ballard DW; Wadzinski BE
    J Biol Chem; 2005 Oct; 280(43):35974-82. PubMed ID: 16126728
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesis.
    Darwech I; Otero JE; Alhawagri MA; Abu-Amer Y
    J Biol Chem; 2010 Aug; 285(33):25522-30. PubMed ID: 20534585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages.
    Awuh JA; Haug M; Mildenberger J; Marstad A; Do CP; Louet C; Stenvik J; Steigedal M; Damås JK; Halaas Ø; Flo TH
    Proc Natl Acad Sci U S A; 2015 Aug; 112(31):E4272-80. PubMed ID: 26195781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization.
    Banga J; Srinivasan D; Sun CC; Thompson CD; Milletti F; Huang KS; Hamilton S; Song S; Hoffman AF; Qin YG; Matta B; LaPan M; Guo Q; Lu G; Li D; Qian H; Bolin DR; Liang L; Wartchow C; Qiu J; Downing M; Narula S; Fotouhi N; DeMartino JA; Tan SL; Chen G; Barnes BJ
    Sci Adv; 2020 May; 6(20):eaay1057. PubMed ID: 32440537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.