These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 25330363)

  • 1. Novel approach for identifying key residues in enzymatic reactions: proton abstraction in ketosteroid isomerase.
    Ito M; Brinck T
    J Phys Chem B; 2014 Nov; 118(46):13050-8. PubMed ID: 25330363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hybrid quantum/classical molecular dynamics simulations of the proton transfer reactions catalyzed by ketosteroid isomerase: analysis of hydrogen bonding, conformational motions, and electrostatics.
    Chakravorty DK; Soudackov AV; Hammes-Schiffer S
    Biochemistry; 2009 Nov; 48(44):10608-19. PubMed ID: 19799395
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of the hydrogen-bond network involving a tyrosine triad in the active site to the structure and function of a highly proficient ketosteroid isomerase from Pseudomonas putida biotype B.
    Kim DH; Jang DS; Nam GH; Choi G; Kim JS; Ha NC; Kim MS; Oh BH; Choi KY
    Biochemistry; 2000 Apr; 39(16):4581-9. PubMed ID: 10769113
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational study of ketosteroid isomerase: insights from molecular dynamics simulation of enzyme bound substrate and intermediate.
    Mazumder D; Kahn K; Bruice TC
    J Am Chem Soc; 2003 Jun; 125(25):7553-61. PubMed ID: 12812495
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of the energetics of the concerted acid-base mechanism in enzymatic catalysis: the case of ketosteroid isomerase.
    Fried SD; Boxer SG
    J Phys Chem B; 2012 Jan; 116(1):690-7. PubMed ID: 22148842
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of mutation on proton transfer reactions in ketosteroid isomerase: insights from molecular dynamics simulations.
    Chakravorty DK; Hammes-Schiffer S
    J Am Chem Soc; 2010 Jun; 132(21):7549-55. PubMed ID: 20450180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Experimental evidence for enzyme-enhanced coupled motion/quantum mechanical hydrogen tunneling by ketosteroid isomerase.
    Wilde TC; Blotny G; Pollack RM
    J Am Chem Soc; 2008 May; 130(20):6577-85. PubMed ID: 18426205
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
    Cho HS; Choi G; Choi KY; Oh BH
    Biochemistry; 1998 Jun; 37(23):8325-30. PubMed ID: 9622484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular dynamics and quantum chemical studies on the catalytic mechanism of Delta5-3-ketosteroid isomerase: the catalytic diad versus the cooperative hydrogen bond mechanism.
    Park H; Merz KM
    J Am Chem Soc; 2003 Jan; 125(4):901-11. PubMed ID: 12537487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase.
    Jang DS; Choi G; Cha HJ; Shin S; Hong BH; Lee HJ; Lee HC; Choi KY
    Mol Cells; 2015 May; 38(5):409-15. PubMed ID: 25947291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.
    Kim SW; Cha SS; Cho HS; Kim JS; Ha NC; Cho MJ; Joo S; Kim KK; Choi KY; Oh BH
    Biochemistry; 1997 Nov; 36(46):14030-6. PubMed ID: 9369474
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kemp Eliminase Activity of Ketosteroid Isomerase.
    Lamba V; Sanchez E; Fanning LR; Howe K; Alvarez MA; Herschlag D; Forconi M
    Biochemistry; 2017 Jan; 56(4):582-591. PubMed ID: 28045505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.
    Nam GH; Cha SS; Yun YS; Oh YH; Hong BH; Lee HS; Choi KY
    Biochem J; 2003 Oct; 375(Pt 2):297-305. PubMed ID: 12852789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A theoretical model of the catalytic mechanism of the Delta5-3-ketosteroid isomerase reaction.
    Sharma K; Vázquez-Ramírez R; Kubli-Garfias C
    Steroids; 2006 Jul; 71(7):549-57. PubMed ID: 16620897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Temperature effects on the catalytic activity of the D38E mutant of 3-oxo-Delta5-steroid isomerase: favorable enthalpies and entropies of activation relative to the nonenzymatic reaction catalyzed by acetate ion.
    Houck WJ; Pollack RM
    J Am Chem Soc; 2004 Dec; 126(50):16416-25. PubMed ID: 15600343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determining the catalytic role of remote substrate binding interactions in ketosteroid isomerase.
    Schwans JP; Kraut DA; Herschlag D
    Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14271-5. PubMed ID: 19706511
    [TBL] [Abstract][Full Text] [Related]  

  • 17. QM/MM modelling of ketosteroid isomerase reactivity indicates that active site closure is integral to catalysis.
    van der Kamp MW; Chaudret R; Mulholland AJ
    FEBS J; 2013 Jul; 280(13):3120-31. PubMed ID: 23356661
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 15N NMR relaxation studies of Y14F mutant of ketosteroid isomerase: the influence of mutation on backbone mobility.
    Lee HJ; Yoon YJ; Jang DS; Kim C; Cha HJ; Hong BH; Choi KY; Lee HC
    J Biochem; 2008 Aug; 144(2):159-66. PubMed ID: 18424811
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A tale of two isomerases: compact versus extended active sites in ketosteroid isomerase and phosphoglucose isomerase.
    Somarowthu S; Brodkin HR; D'Aquino JA; Ringe D; Ondrechen MJ; Beuning PJ
    Biochemistry; 2011 Nov; 50(43):9283-95. PubMed ID: 21970785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rapid Estimation of Catalytic Efficiency by Cumulative Atomic Multipole Moments: Application to Ketosteroid Isomerase Mutants.
    Beker W; van der Kamp MW; Mulholland AJ; Sokalski WA
    J Chem Theory Comput; 2017 Feb; 13(2):945-955. PubMed ID: 28103023
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.