BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 25333254)

  • 1. Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.
    Sison EA; Magoon D; Li L; Annesley CE; Rau RE; Small D; Brown P
    Oncotarget; 2014 Oct; 5(19):8947-58. PubMed ID: 25333254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML.
    Sison EA; McIntyre E; Magoon D; Brown P
    Mol Cancer Res; 2013 Sep; 11(9):1004-16. PubMed ID: 23754844
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment.
    Tabe Y; Shi YX; Zeng Z; Jin L; Shikami M; Hatanaka Y; Miida T; Hsu FJ; Andreeff M; Konopleva M
    PLoS One; 2013; 8(6):e62785. PubMed ID: 23826077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dose-dependent manner resulting in increased susceptibility of BCR-ABL+ cell to Imatinib and Nilotinib.
    Dillmann F; Veldwijk MR; Laufs S; Sperandio M; Calandra G; Wenz F; Zeller J; Fruehauf S
    Leuk Lymphoma; 2009 Oct; 50(10):1676-86. PubMed ID: 19657955
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.
    Zeng Z; Shi YX; Samudio IJ; Wang RY; Ling X; Frolova O; Levis M; Rubin JB; Negrin RR; Estey EH; Konoplev S; Andreeff M; Konopleva M
    Blood; 2009 Jun; 113(24):6215-24. PubMed ID: 18955566
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.
    Gravina GL; Mancini A; Muzi P; Ventura L; Biordi L; Ricevuto E; Pompili S; Mattei C; Di Cesare E; Jannini EA; Festuccia C
    Prostate; 2015 Sep; 75(12):1227-46. PubMed ID: 26073897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemosensitivity is differentially regulated by the SDF-1/CXCR4 and SDF-1/CXCR7 axes in acute lymphoblastic leukemia with MLL gene rearrangements.
    Ando N; Furuichi Y; Kasai S; Tamai M; Harama D; Kagami K; Abe M; Goi K; Inukai T; Sugita K
    Leuk Res; 2018 Dec; 75():36-44. PubMed ID: 30453100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL.
    Sison EA; Magoon D; Li L; Annesley CE; Romagnoli B; Douglas GJ; Tuffin G; Zimmermann J; Brown P
    Oncotarget; 2015 Oct; 6(31):30902-18. PubMed ID: 26360610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism.
    Sison EA; Rau RE; McIntyre E; Li L; Small D; Brown P
    Br J Haematol; 2013 Mar; 160(6):785-97. PubMed ID: 23294096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A phase 1 study of the CXCR4 antagonist plerixafor in combination with high-dose cytarabine and etoposide in children with relapsed or refractory acute leukemias or myelodysplastic syndrome: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study (POE 10-03).
    Cooper TM; Sison EAR; Baker SD; Li L; Ahmed A; Trippett T; Gore L; Macy ME; Narendran A; August K; Absalon MJ; Boklan J; Pollard J; Magoon D; Brown PA
    Pediatr Blood Cancer; 2017 Aug; 64(8):. PubMed ID: 28409853
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib.
    Weisberg E; Azab AK; Manley PW; Kung AL; Christie AL; Bronson R; Ghobrial IM; Griffin JD
    Leukemia; 2012 May; 26(5):985-90. PubMed ID: 22182920
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A CXCR4 antagonist leads to tumor suppression by activation of immune cells in a leukemia-induced microenvironment.
    Han AR; Lee JY; Kim HJ; Min WS; Park G; Kim SH
    Oncol Rep; 2015 Dec; 34(6):2880-8. PubMed ID: 26398122
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis.
    Kato I; Niwa A; Heike T; Fujino H; Saito MK; Umeda K; Hiramatsu H; Ito M; Morita M; Nishinaka Y; Adachi S; Ishikawa F; Nakahata T
    PLoS One; 2011; 6(11):e27042. PubMed ID: 22069486
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro.
    Juarez J; Bradstock KF; Gottlieb DJ; Bendall LJ
    Leukemia; 2003 Jul; 17(7):1294-300. PubMed ID: 12835717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation.
    Ngamsri KC; Jans C; Putri RA; Schindler K; Gamper-Tsigaras J; Eggstein C; Köhler D; Konrad FM
    Front Immunol; 2020; 11():407. PubMed ID: 32210974
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas.
    Grymula K; Tarnowski M; Wysoczynski M; Drukala J; Barr FG; Ratajczak J; Kucia M; Ratajczak MZ
    Int J Cancer; 2010 Dec; 127(11):2554-68. PubMed ID: 20162608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML.
    Agarwal A; Fleischman AG; Petersen CL; MacKenzie R; Luty S; Loriaux M; Druker BJ; Woltjer RL; Deininger MW
    Blood; 2012 Sep; 120(13):2658-68. PubMed ID: 22889761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma.
    Waldschmidt JM; Simon A; Wider D; Müller SJ; Follo M; Ihorst G; Decker S; Lorenz J; Chatterjee M; Azab AK; Duyster J; Wäsch R; Engelhardt M
    Br J Haematol; 2017 Oct; 179(1):36-49. PubMed ID: 28670693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug design strategies focusing on the CXCR4/CXCR7/CXCL12 pathway in leukemia and lymphoma.
    Barbieri F; Bajetto A; Thellung S; Würth R; Florio T
    Expert Opin Drug Discov; 2016 Nov; 11(11):1093-1109. PubMed ID: 27598329
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.
    Zeng Z; Samudio IJ; Munsell M; An J; Huang Z; Estey E; Andreeff M; Konopleva M
    Mol Cancer Ther; 2006 Dec; 5(12):3113-21. PubMed ID: 17172414
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.