BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 25333894)

  • 1. Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1α signaling pathway.
    Chen F; Zhuang M; Zhong C; Peng J; Wang X; Li J; Chen Z; Huang Y
    Oncol Rep; 2015 Jan; 33(1):457-63. PubMed ID: 25333894
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism.
    Xuan Y; Hur H; Ham IH; Yun J; Lee JY; Shim W; Kim YB; Lee G; Han SU; Cho YK
    Exp Cell Res; 2014 Feb; 321(2):219-30. PubMed ID: 24342832
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway.
    Wang H; Zhao L; Zhu LT; Wang Y; Pan D; Yao J; You QD; Guo QL
    Mol Carcinog; 2014 Feb; 53 Suppl 1():E107-18. PubMed ID: 23761018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway.
    Gong T; Cui L; Wang H; Wang H; Han N
    J Transl Med; 2018 Jun; 16(1):164. PubMed ID: 29898734
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    Zeng L; Zhou HY; Tang NN; Zhang WF; He GJ; Hao B; Feng YD; Zhu H
    World J Gastroenterol; 2016 May; 22(20):4868-80. PubMed ID: 27239113
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway.
    Sun LT; Zhang LY; Shan FY; Shen MH; Ruan SM
    Chin J Nat Med; 2021 Feb; 19(2):143-152. PubMed ID: 33641785
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells.
    Woo YM; Shin Y; Lee EJ; Lee S; Jeong SH; Kong HK; Park EY; Kim HK; Han J; Chang M; Park JH
    PLoS One; 2015; 10(7):e0132285. PubMed ID: 26158266
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer.
    Sun XP; Dong X; Lin L; Jiang X; Wei Z; Zhai B; Sun B; Zhang Q; Wang X; Jiang H; Krissansen GW; Qiao H; Sun X
    FEBS J; 2014 Jan; 281(1):115-28. PubMed ID: 24165223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Baicalein resensitizes tamoxifen-resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia-inducible factor-1α.
    Chen Y; Zhang J; Zhang M; Song Y; Zhang Y; Fan S; Ren S; Fu L; Zhang N; Hui H; Shen X
    Clin Transl Med; 2021 Nov; 11(11):e577. PubMed ID: 34841716
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
    Dong S; Liang S; Cheng Z; Zhang X; Luo L; Li L; Zhang W; Li S; Xu Q; Zhong M; Zhu J; Zhang G; Hu S
    J Exp Clin Cancer Res; 2022 Jan; 41(1):15. PubMed ID: 34998404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Baicalein suppresses hypoxia-induced HIF-1alpha protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells.
    Hwang KY; Oh YT; Yoon H; Lee J; Kim H; Choe W; Kang I
    Neurosci Lett; 2008 Oct; 444(3):264-9. PubMed ID: 18771709
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells.
    Lau CK; Yang ZF; Ho DW; Ng MN; Yeoh GC; Poon RT; Fan ST
    Clin Cancer Res; 2009 May; 15(10):3462-71. PubMed ID: 19447872
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-β signaling pathway.
    Chen F; Zhuang M; Peng J; Wang X; Huang T; Li S; Lin M; Lin H; Xu Y; Li J; Chen Z; Huang Y
    Mol Med Rep; 2014 Oct; 10(4):1999-2003. PubMed ID: 25109410
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia-inducible factor-1 in human hepatoma HepG2 cells.
    Dai Q; Yin Q; Wei L; Zhou Y; Qiao C; Guo Y; Wang X; Ma S; Lu N
    Mol Carcinog; 2016 Aug; 55(8):1275-89. PubMed ID: 26259145
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer.
    Liu L; Ning X; Sun L; Zhang H; Shi Y; Guo C; Han S; Liu J; Sun S; Han Z; Wu K; Fan D
    Cancer Sci; 2008 Jan; 99(1):121-8. PubMed ID: 17953712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gefitinib circumvents hypoxia-induced drug resistance by the modulation of HIF-1alpha.
    Rho JK; Choi YJ; Lee JK; Ryoo BY; Na II; Yang SH; Kim CH; Yoo YD; Lee JC
    Oncol Rep; 2009 Mar; 21(3):801-7. PubMed ID: 19212642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oleanolic acid reduces aerobic glycolysis-associated proliferation by inhibiting yes-associated protein in gastric cancer cells.
    Li Y; Xu Q; Yang W; Wu T; Lu X
    Gene; 2019 Sep; 712():143956. PubMed ID: 31271843
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy.
    Nakamura J; Kitajima Y; Kai K; Hashiguchi K; Hiraki M; Noshiro H; Miyazaki K
    Int J Cancer; 2010 Sep; 127(5):1158-71. PubMed ID: 20020496
    [TBL] [Abstract][Full Text] [Related]  

  • 19. YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.
    Sun HL; Liu YN; Huang YT; Pan SL; Huang DY; Guh JH; Lee FY; Kuo SC; Teng CM
    Oncogene; 2007 Jun; 26(27):3941-51. PubMed ID: 17213816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of hypoxia on HIF
    Wang L; Xing W; Qi J; Lu Y; Xiang L; Zhou Y
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2022 Dec; 47(12):1629-1636. PubMed ID: 36748372
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.