These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 25339109)

  • 1. Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.
    Manevski N; Swart P; Balavenkatraman KK; Bertschi B; Camenisch G; Kretz O; Schiller H; Walles M; Ling B; Wettstein R; Schaefer DJ; Itin P; Ashton-Chess J; Pognan F; Wolf A; Litherland K
    Drug Metab Dispos; 2015 Jan; 43(1):126-39. PubMed ID: 25339109
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aldehyde oxidase activity in fresh human skin.
    Manevski N; Balavenkatraman KK; Bertschi B; Swart P; Walles M; Camenisch G; Schiller H; Kretz O; Ling B; Wettstein R; Schaefer DJ; Pognan F; Wolf A; Litherland K
    Drug Metab Dispos; 2014 Dec; 42(12):2049-57. PubMed ID: 25249692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A study of inter-individual variability in the Phase II metabolism of xenobiotics in human skin.
    Spriggs S; Cubberley R; Loadman P; Sheffield D; Wierzbicki A
    Toxicol Lett; 2018 Aug; 292():63-72. PubMed ID: 29709425
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites.
    Zamek-Gliszczynski MJ; Hoffmaster KA; Nezasa K; Tallman MN; Brouwer KL
    Eur J Pharm Sci; 2006 Apr; 27(5):447-86. PubMed ID: 16472997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assessment of catechol induction and glucuronidation in rat liver microsomes.
    Elovaara E; Mikkola J; Luukkanen L; Antonio L; Fournel-Gigleux S; Burchell B; Magdalou J; Taskinen J
    Drug Metab Dispos; 2004 Dec; 32(12):1426-33. PubMed ID: 15371300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interindividual variability in 2-hydroxylation, 3-sulfation, and 3-glucuronidation of ethynylestradiol in human liver.
    Shiraga T; Niwa T; Ohno Y; Kagayama A
    Biol Pharm Bull; 2004 Dec; 27(12):1900-6. PubMed ID: 15577203
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Highly variable pH effects on the interaction of diclofenac and indomethacin with human UDP-glucuronosyltransferases.
    Zhang H; Soikkeli A; Tolonen A; Rousu T; Hirvonen J; Finel M
    Toxicol In Vitro; 2012 Dec; 26(8):1286-93. PubMed ID: 22265884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats: evidence for bioactivation through alcohol-O-glucuronidation and O-sulfation.
    Cui D; Rankin GO; Harvison PJ
    Chem Res Toxicol; 2005 Jun; 18(6):991-1003. PubMed ID: 15962934
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of chromium and cobalt ions on phase I and phase II enzymatic activities in vitro in freshly isolated rat hepatocytes.
    Afolaranmi GA; Henderson C; Grant MH
    Toxicol In Vitro; 2011 Feb; 25(1):125-30. PubMed ID: 20946949
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.
    Grillo MP; Hua F; Knutson CG; Ware JA; Li C
    Chem Res Toxicol; 2003 Nov; 16(11):1410-7. PubMed ID: 14615966
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of human glutathione S-transferases on glutathione-dependent inactivation of cytochrome P450-dependent reactive intermediates of diclofenac.
    Dragovic S; Boerma JS; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2013 Nov; 26(11):1632-41. PubMed ID: 24083800
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of acetaminophen sulfation by 2,6-dichloro-4-nitrophenol in the perfused rat liver preparation. Lack of a compensatory increase of glucuronidation.
    Fayz S; Cherry WF; Dawson JR; Mulder GJ; Pang KS
    Drug Metab Dispos; 1984; 12(3):323-9. PubMed ID: 6145559
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucuronidation and sulfation in subcellular fractions and in the isolated perfused rabbit lung: influence of ethanol.
    Yang CM; Carlson GP
    Pharmacology; 1991; 42(1):28-35. PubMed ID: 1905411
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unusual glucuronides.
    Argikar UA
    Drug Metab Dispos; 2012 Jul; 40(7):1239-51. PubMed ID: 22517971
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of phase II in vitro metabolites using homogenized horse liver.
    Wong JK; Chan GH; Leung DK; Tang FP; Wan TS
    Drug Test Anal; 2016 Feb; 8(2):241-7. PubMed ID: 26352508
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-Glucuronidation of the antiepileptic drug retigabine: results from studies with human volunteers, heterologously expressed human UGTs, human liver, kidney, and liver microsomal membranes of Crigler-Najjar type II.
    Borlak J; Gasparic A; Locher M; Schupke H; Hermann R
    Metabolism; 2006 Jun; 55(6):711-21. PubMed ID: 16713428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stimulation of estradiol glucuronidation: a protective mechanism against estradiol-mediated carcinogenesis?
    Pfeiffer E; Graf E; Gerstner S; Metzler M
    Mol Nutr Food Res; 2006 Apr; 50(4-5):385-9. PubMed ID: 16598814
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation.
    Riches Z; Bloomer J; Patel A; Nolan A; Coughtrie M
    Xenobiotica; 2009 May; 39(5):374-81. PubMed ID: 19280384
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment of the metabolism and intrinsic reactivity of a novel catechol metabolite.
    Hutzler JM; Melton RJ; Rumsey JM; Thompson DC; Rock DA; Wienkers LC
    Chem Res Toxicol; 2008 May; 21(5):1125-33. PubMed ID: 18407675
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparison of the metabolism of 10 chemicals in human and pig skin explants.
    Géniès C; Jamin EL; Debrauwer L; Zalko D; Person EN; Eilstein J; Grégoire S; Schepky A; Lange D; Ellison C; Roe A; Salhi S; Cubberley R; Hewitt NJ; Rothe H; Klaric M; Duplan H; Jacques-Jamin C
    J Appl Toxicol; 2019 Feb; 39(2):385-397. PubMed ID: 30345528
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.